Patents by Inventor Peter Keith

Peter Keith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190171278
    Abstract: Power reduction and voltage adjustment techniques for computing systems and processing devices are presented herein. In one example, a method includes executing a voltage characterization service for a processing device of a computing apparatus to determine at least one supply voltage for the processing device, the voltage characterization service comprising a functional test that exercises the processing device at iteratively adjusted voltages in context with associated system elements of the computing apparatus. During execution of the voltage characterization service, the method includes monitoring for operational failures of at least the processing device, and responsive to the operational failures, determining at least one resultant supply voltage.
    Type: Application
    Filed: January 28, 2019
    Publication date: June 6, 2019
    Inventors: William Paul Hovis, Garrett Douglas Blankenburg, Peter Anthony Atkinson, Robert James Ray, Andres Felipe Hernandez Mojica, Samy Boshra-Riad, Erng-Sing Wee, Brian Keith Langendorf
  • Patent number: 10310572
    Abstract: Thermal reduction and voltage adjustment techniques for computing systems and processing devices are presented herein. In a first example, a method of operating a voltage control system for a processing device includes operating the processing device in a computing assembly at a selected performance level, the processing device supplied with at least one input voltage at a first voltage level. The method includes monitoring thermal information associated with the computing assembly, and when the thermal information indicates a temperature associated with the computing assembly exceeds a threshold temperature, adjusting the at least one input voltage level supplied to the processing device to a second voltage level lower than the first voltage level and continuing to operate the processing device at the selected performance level.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: June 4, 2019
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: William Paul Hovis, Garrett Douglas Blankenburg, Peter Anthony Atkinson, Robert James Ray, Andres Felipe Hernandez Mojica, Samy Boshra-Riad, Erng-Sing Wee, Brian Keith Langendorf
  • Publication number: 20180051326
    Abstract: Mutations that affect mRNA splicing often produce multiple mRNA isoforms containing different exon structures. Definition of an exon and its inclusion in mature mRNA relies on joint recognition of both acceptor and donor splice sites. The instant methodology predicts cryptic and exon skipping isoforms in mRNA produced by splicing mutations from the combined information contents and the distribution of the splice sites and other regulatory binding sites defining these exons. In its simplest form, the total information content of an exon, Ri,total, is the sum of the information contents of its corresponding acceptor and donor splice sites, adjusted for the self-information of the exon length. Differences between Ri,total values of mutant versus normal exons that are concordant with gene expression data demonstrate alterations in the structures and relative abundance of the mRNA transcripts resulting from these mutations.
    Type: Application
    Filed: October 10, 2017
    Publication date: February 22, 2018
    Inventors: Peter Keith Rogan, Eliseos John Mucaki
  • Patent number: 9868649
    Abstract: The invention relates to a process and apparatus that treats waste water, in particular waste water containing surfactants and including grey water, for local reuse. According to the invention, the process comprises a) collecting waste water in a reservoir; b) injecting gas into waste water from the reservoir to form bubbles in the waste water; c) separating the bubbles, and any entrained contaminants, from the waste water; d) drying the separated bubbles and returning any water recovered from the dried bubbles to the waste water undergoing treatment; e) optionally repeating steps b) to d) to achieve the desired purification of the waste water; and f) collecting the purified waste water. The invention provides a robust process and a mechanically simple apparatus that does not require regular replacement of chemicals or filters, yet is capable of treating waste water locally, and in particular grey water for household reuse.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: January 16, 2018
    Assignee: Nexus eWater Pty Ltd.
    Inventors: William Peter Keith Kennedy, Andrew James Hermann, Thomas Andrew Wood
  • Patent number: 9624549
    Abstract: A method for determining genes in breast cancer that are stable in copy number, expression and sequence in tumors from nearly all patients. Certain stable genes are targets of standard chemotherapy. The effectiveness of therapies that act upon these targets depends on maintaining the stability and integrity of these genes in tumors. Mutations in these targets result in poor response to therapies that target these gene products. In the instant invention, ordinarily stable gene targets are characterized as either normal or mutant for the purpose of determining whether to include or exclude particular drugs as potential treatments.
    Type: Grant
    Filed: January 18, 2013
    Date of Patent: April 18, 2017
    Assignee: Cytognomix Inc.
    Inventors: Peter Keith Rogan, Joan Helen Knoll
  • Patent number: 9198757
    Abstract: The various aspects of the invention pertain to devices and related methods for treating heart conditions, including, for example, dilatation, valve incompetencies, including mitral valve leakage, and other similar heart failure conditions. The devices and related methods of the present invention operate to assist in the apposition of heart valve leaflets to improve valve function. According to one aspect of the invention, a method improves the function of a valve of a heart by placing an elongate member transverse a heart chamber so that each end of the elongate member extends through a wall of the heart, and placing first and second anchoring members external the chamber. The first and second anchoring members are attached to first and second ends of the elongate member to fix the elongate member in a position across the chamber so as to reposition papillary muscles within the chamber.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: December 1, 2015
    Assignee: Edwards Lifesciences, LLC
    Inventors: Richard Schroeder, Robert Vidlund, Jason Kalgreen, Cyril Schweich, Jr., Todd Mortier, Marc Simmon, Peter Keith
  • Patent number: 9138219
    Abstract: Embodiments relate to implantable devices for the treatment of syndesmosis injuries. Embodiments include a first anchor attachable to a first bone, the first anchor being coupled to a flexible component, the flexible component in turn being coupled to a base component. The base component may be rigid, and may be externally threaded for engaging with a second anchor. Position of the second anchor may be adjusted by rotating the second anchor with respect to the base component, thereby adjusting relative position of the two bones. An assembly may be created in which an outer tube contains the flexible component and the base component inside the outer tube, and at its distal end the outer tube may engage the first anchor so as to allow transmission of torque. The outer tube may be withdrawn proximally after implantation of the first anchor. The bones may be a tibia and a fibula.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: September 22, 2015
    Assignee: Tarsus Medical Inc.
    Inventors: Chuck Horrell, Paul M. Sand, Peter Keith, Trevor Lofthouse, Nick Mourlas, John Avi Roop, Jason W. Lettmann
  • Publication number: 20150254397
    Abstract: A method is described for the automatic validation of DNA sequencing variants that alter mRNA splicing from nucleic acids isolated from a patient or tissue sample. Evidence the a predicted splicing mutation is demonstrated by performing statistically valid comparisons between sequence read counts of abnormal RNA species in mutant versus non-mutant tissues. The method leverages large numbers of control samples to corroborate the consequences of predicted splicing variants in complete genomes and exomes for individuals carrying such mutations. Because the method examines all transcript evidence in a genome, it is not necessary a priori to know which gene or genes carry a splicing mutation.
    Type: Application
    Filed: January 10, 2015
    Publication date: September 10, 2015
    Applicant: Cytognomix Inc
    Inventors: PETER KEITH ROGAN, STEPHANIE NICOLE DORMAN, COBY VINER, ELISEOS JOHN MUCAKI
  • Publication number: 20140206543
    Abstract: A method for determining genes in breast cancer that are stable in copy number, expression and sequence in tumors from nearly all patients. Certain stable genes are targets of standard chemotherapy. The effectiveness of therapies that act upon these targets depends on maintaining the stability and integrity of these genes in tumors. Mutations in these targets result in poor response to therapies that target these gene products. In the instant invention, ordinarily stable gene targets are characterized as either normal or mutant for the purpose of determining whether to include or exclude particular drugs as potential treatments.
    Type: Application
    Filed: January 18, 2013
    Publication date: July 24, 2014
    Inventors: Peter Keith Rogan, Joan Helen Knoll
  • Publication number: 20140199698
    Abstract: Mutations that affect mRNA splicing often produce multiple mRNA isoforms containing different exon structures. Definition of an exon and its inclusion in mature mRNA relies on joint recognition of both acceptor and donor splice sites. The instant methodology predicts cryptic and exon skipping isoforms in mRNA produced by splicing mutations from the combined information contents and the distribution of the splice sites and other regulatory binding sites defining these exons. In its simplest form, the total information content of an exon, Ri,total, is the sum of the information contents of its corresponding acceptor and donor splice sites, adjusted for the self-information of the exon length. Differences between Ri,total values of mutant versus normal exons are consistent with the relative abundance of these exons in distinct processed mRNAs.
    Type: Application
    Filed: January 14, 2014
    Publication date: July 17, 2014
    Inventors: Peter Keith Rogan, Eliseos John Mucaki
  • Publication number: 20140025143
    Abstract: Devices and methods that mitigate reperfusion injury (RI) in a clinically practical manner so as to avoid significantly increasing time to reperfusion. In general, these systems and methods involve an antegrade approach to deliver a fluid to the myocardium at risk of RI before, during and after reperfusion is established by a percutaneous coronary intervention such as aspiration and stenting.
    Type: Application
    Filed: July 16, 2013
    Publication date: January 23, 2014
    Applicant: Prospex Medical III
    Inventors: Robert Atkinson, Jason Galdonik, Peter Keith, Paul McLean
  • Patent number: 8605981
    Abstract: A method for determining radiation exposure from chromosome abnormalities present in a specimen by determining the location or locations of the centromere of each chromosome in a cell in an image of a metaphase cell by segmentation of an accurately drawn chromosome centerline followed by selection of a longitudinal cross-section with the minimum width or intensity or width and intensity; counting the number of centromeres in each chromosome in each cell; computing the frequency of dicentric chromosomes in a population of cells; and determining the radiation dose by comparing the computed frequency of dicentric chromosomes with a previously determined dose-response curve from a calibrated source.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: December 10, 2013
    Assignee: Cytognomix Inc.
    Inventors: Peter Keith Rogan, Joan Helen Knoll, Jagath Samarabandu, Akila Subasinghe
  • Publication number: 20130319947
    Abstract: The invention relates to a process and apparatus that treats waste water, in particular waste water containing surfactants and including grey water, for local reuse. According to the invention, the process comprises a) collecting waste water in a reservoir; b) injecting gas into waste water from the reservoir to form bubbles in the waste water; c) separating the bubbles, and any entrained contaminants, from the waste water; d) drying the separated bubbles and returning any water recovered from the dried bubbles to the waste water undergoing treatment; e) optionally repeating steps b) to d) to achieve the desired purification of the waste water; and f) collecting the purified waste water.
    Type: Application
    Filed: June 24, 2011
    Publication date: December 5, 2013
    Inventor: William Peter Keith Kennedy
  • Publication number: 20130216118
    Abstract: A method for determining radiation exposure from chromosome abnormalities present in a specimen by determining the location or locations of the centromere of each chromosome in a cell in an image of a metaphase cell by segmentation of an accurately drawn chromosome centerline followed by selection of a longitudinal cross-section with the minimum width or intensity or width and intensity; counting the number of centromeres in each chromosome in each cell; computing the frequency of dicentric chromosomes in a population of cells; and determining the radiation dose by comparing the computed frequency of dicentric chromosomes with a previously determined dose-response curve from a calibrated source.
    Type: Application
    Filed: November 4, 2011
    Publication date: August 22, 2013
    Inventors: Peter Keith Rogan, Joan Helen Knoll, Jagath Samarabandu, Akila Subasinghe
  • Publication number: 20120290037
    Abstract: Baroreflex activation is achieved by providing suitable control signals to a baroreflex activation device. A method comprises establishing a therapy interval within the therapy interval, establishing a plurality of dose intervals, and generating an electrical output signal. The electrical output signal has a time dependence such that the average electrical power applied to the baroreflex activation device differs between first and second portions of at least some dose intervals. Another method comprises establishing a series of therapy interval portions, during at least some therapy intervals, establishing a plurality of burst intervals, and generating an electrical output signal. The electrical output signal has a time dependence such that the average electrical power applied to the baroreflex activation device differs between first and second portions of the therapy intervals and also differs between first and second portions of at least some burst intervals.
    Type: Application
    Filed: June 27, 2012
    Publication date: November 15, 2012
    Applicant: CVRX, INC.
    Inventors: Robert S. Kieval, David J. Serdar, Bruce J. Persson, Peter Keith
  • Publication number: 20120172936
    Abstract: The various embodiments disclosed herein relate to implantable devices for the treatment of syndesmosis injuries. More specifically, the various embodiments include systems, devices, and methods for implantation of an implantable device having at least one bone anchor for treating such injuries.
    Type: Application
    Filed: July 15, 2011
    Publication date: July 5, 2012
    Applicant: TARSUS MEDICAL INC.
    Inventors: Chuck Horrell, Paul M. Sand, Peter Keith, Trevor Lofthouse, Nick Mourlas, John Avi Roop, Jason W. Lettmann
  • Patent number: 7766812
    Abstract: The various aspects of the invention pertain to devices and related methods for treating heart conditions, including, for example, dilatation, valve incompetencies, including mitral valve leakage, and other similar heart failure conditions. The devices and related methods of the present invention operate to assist in the apposition of heart valve leaflets to improve valve function. According to one aspect of the invention, a method improves the function of a valve of a heart by placing an elongate member transverse a heart chamber so that each end of the elongate member extends through a wall of the heart, and placing first and second anchoring members external the chamber. The first and second anchoring members are attached to first and second ends of the elongate member to fix the elongate member in a position across the chamber so as to reposition papillary muscles within the chamber.
    Type: Grant
    Filed: April 14, 2006
    Date of Patent: August 3, 2010
    Assignee: Edwards Lifesciences LLC
    Inventors: Richard Schroeder, Robert Vidlund, Jason Kalgreen, Cyril Schweich, Jr., Todd Mortier, Marc Simmon, Peter Keith
  • Publication number: 20090270980
    Abstract: The various aspects of the invention pertain to devices and related methods for treating heart conditions, including, for example, dilatation, valve incompetencies, including mitral valve leakage, and other similar heart failure conditions. The devices and related methods of the present invention operate to assist in the apposition of heart valve leaflets to improve valve function. According to one aspect of the invention, a method improves the function of a valve of a heart by placing an elongate member transverse a heart chamber so that each end of the elongate member extends through a wall of the heart, and placing first and second anchoring members external the chamber. The first and second anchoring members are attached to first and second ends of the elongate member to fix the elongate member in a position across the chamber so as to reposition papillary muscles within the chamber.
    Type: Application
    Filed: July 7, 2009
    Publication date: October 29, 2009
    Inventors: Richard F. Schroeder, Robert Vidlund, Jason Kalgreen, Cyril Schweich, JR., Todd Mortier, Marc Simmon, Peter Keith
  • Publication number: 20080097540
    Abstract: A monitoring device is provided to monitor a patient. The monitoring device includes at least one lead having an electrode. The lead is positioned proximate a location within the patient's body, and the lead is adapted to sense cardiac electrical activity. The monitoring device also includes a control system coupled to the at least one lead to receive a signal representative of the cardiac electrical activity.
    Type: Application
    Filed: December 14, 2007
    Publication date: April 24, 2008
    Applicant: CVRx, Inc.
    Inventors: Stephen Bolea, Robert Kieval, Bruce Persson, David Serdar, Peter Keith, Eric Irwin, Martin Rossing
  • Publication number: 20080033353
    Abstract: A method of treating a constricted sinus passageway in a frontal sinus of a patient includes forming an artificial passageway into the frontal sinus of the patient with a tool. An elongate member having an inflation member thereon is inserted through the passageway. The inflation member is positioned with the constricted sinus passageway and the inflation member is expanded so as to expand at least a portion of the constricted sinus passageway.
    Type: Application
    Filed: July 24, 2007
    Publication date: February 7, 2008
    Applicant: ENTELLUS MEDICAL, INC.
    Inventors: Theodore Truitt, Thomas Ressemann, Peter Keith