Abstract: Disclosed herein are apparatuses and methods for intraoperative on-demand implant customization in a surgical setting. An apparatus may include a storage portion, an implant customization portion and an interface. The storage portion may house implant blanks and implant accessories. The implant customization portion may customize the implant blanks. The interface may be configured to receive implant customization information and utilize the same to intraoperatively manipulate the implant blank to a patient-specific implant within a sterile environment. A method to customize an implant in a surgical care environment may include the steps of obtaining information related to the implant location, selecting an implant blank based on the information, and customizing the implant blank in a surgical care setting with a customization apparatus.

Abstract: The present invention relates to a process for preparing esters from fatty alcohols, in which fatty alcohols and fatty acids are reacted in the presence of an enzyme at a temperature in the range of 30 to 50° C., the water which forms is removed and the reaction is completed under reduced pressure at a temperature of 50 to 80° C.

Abstract: Mixtures of Guerbet alcohols, their use in cosmetic and/or pharmaceutical preparations, and also cosmetic and/or pharmaceutical preparations comprising mixtures of Guerbet alcohols are described. Of suitability as petroleum jelly substitute are in particular Guerbet alcohol mixtures with a melting range, measured by differential scanning calorimetry (DSC), between ?20° C. and +70° C., where the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35±10° C. These are obtainable for example by reacting a) 55 to 95% by weight of cetylstearyl alcohol, b) 5 to 45% by weight of fatty alcohols with a chain length of from 8 to 22 carbon atoms and c) optionally an aliphatic diol having at least 3 carbon atoms.

Abstract: The disclosed invention refers to a process for obtaining fatty acid alkyl esters, rosin acids and sterols from crude tall oil (CTO), which is characterized by the following steps: (a) reacting the free fatty acids present in the CTO with lower alcohols; (b) esterifying the sterols in the CTO with boric acid or transesterifying the sterols with a catalyst; (c) separating the fatty acid lower alkyl esters and rosin acids from the remaining sterol borate esters or sterol esters of fatty acids to produce a stream of sterol esters; (d) separating the fatty acid alkyl esters from the rosin acids to produce a first stream of fatty acid alky esters and a second stream of rosin acids; and (e) converting the sterol esters into the free sterols to produce a third stream of free sterols.

Abstract: Described herein are mixed ethers and cosmetic and/or pharmaceutical preparations comprising mixed ethers. Certain mixed ethers have a melting range between ?25° C. and +70° C., wherein the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35 ±10° C. These mixed ethers are obtainable for example by condensation reaction of a) 25 to 90% by weight of unbranched fatty alcohols with a chain length of 12 to 19 carbon atoms; b) 5 to 50 by weight of isostearyl alcohol; c) 0 to 35% by weight of a fatty alcohol with a chain length of 20 and/or 22 carbon atoms; and d) 0 to 25% by weight of a fatty alcohol having 8 and/or 10 carbon atoms.

Abstract: Described are alkoxylated glycerol acetals according to Formulas (Ia) and (Ib) wherein R1 represents a linear or branched, saturated or unsaturated and optionally substituted hydrocarbyl residue comprising 6 to 22 carbon atoms and 0 or 1 to 3 double bonds, a benzyl or furfuryl radical, R2 is selected from hydrogen, an alkyl, alkenyl or hydroxyalkyl group having 6 to 22 carbon atoms or an acyl group having 6 to 22 carbon atoms and 0 or 1 to 3 double bonds, AO represents an ethylene oxide, a propylene oxide, a butylene oxide unit, or their mixtures, and n is an integer of about 1 to about 100.

Abstract: The present invention relates to a process for preparing esters from fatty alcohols, in which fatty alcohols and fatty acids are reacted in the presence of an enzyme at a temperature in the range of 30 to 50° C., the water which forms is removed and the reaction is completed under reduced pressure at a temperature of 50 to 80° C.

Abstract: The invention relates to a process for production of fatty acids directly from soapstock generated in the alkali refining process including the steps of (a) adding a lipase directly to the alkaline soapstock to facilitate hydrolysis of glycerides without prior neutralization, (b) neutralizing and splitting the soaps with strong acids, and (c) separating the fatty acid phase from the aqueous phase by settling and/or centrifugation. A second embodiment is a process in which the soapstock is first neutralized and split with strong acids, followed by adding a lipase to facilitate glyceride hydrolysis, and separating the fatty acid phase. The fatty acids so obtained can be esterified with C1-C6 alcohols using a lipase that is selective for fatty acids and does not transesterify the sterolesters, and the fatty acid esters and sterolesters are separated by distillation. The sterolesters are useful as supplements for food, as pharmaceutical agents for lowering cholesterol and as biofuel and biodiesel.

Abstract: Described are alkoxylated glycerol acetals according to Formulas (Ia) and (Ib) wherein R1 represents a linear or branched, saturated or unsaturated and optionally substituted hydrocarbyl residue comprising 6 to 22 carbon atoms and 0 or 1 to 3 double bonds, a benzyl or furfuryl radical, R2 is selected from hydrogen, an alkyl, alkenyl or hydroxyalkyl group having 6 to 22 carbon atoms or an acyl group having 6 to 22 carbon atoms and 0 or 1 to 3 double bonds, AO represents an ethylene oxide, a propylene oxide, a butylene oxide unit, or their mixtures, and n is an integer of about 1 to about 100.

Abstract: A process for enriching and separating polyunsaturated fatty acid (PUFA) acyl groups in a fatty acid mixture, which mixture contains other non-PUFA fatty acid acyl groups, is disclosed.

Abstract: The invention relates to a process for production of fatty acids directly from soapstock generated in the alkali refining process including the steps of (a) adding a lipase directly to the alkaline soapstock to facilitate hydrolysis of glycerides without prior neutralisation, (b) neutralizing and splitting the soaps with strong acids, and (c) separating the fatty acid phase from the aqueous phase by settling and/or centrifugation. A second embodiment is a process in which the soapstock is first neutralized and split with strong acids, followed by adding a lipase to facilitate glyceride hydrolysis, and separating the fatty acid phase. The fatty acids so obtained can be esterified with C1-C6 alcohols using a lipase that is selective for fatty acids and does not transesterify the sterolesters, and the fatty acid esters and sterolesters are separated by distillation. The sterolesters are useful as supplements for food, as pharmaceutical agents for lowering cholesterol and as biofuel and biodiesel.

Abstract: A mixture containing fatty acid glycerides which has a high percentage content of PUFA acyl groups and a low percentage content of saturated fatty acid acyl groups is described. A process which enables the PUFA acyl groups in a mixture containing fatty acid glycerides (for example a fish oil) to be enriched and, at the same time, the content of saturated fatty acid acyl groups to be maintained at a low content is described. The process is a hydrolytic process or an alcoholysis in which the fatty acid acyl groups to be enriched are hydrolytically or alcoholytically released from the fatty acid glycerides slowly, if at all, the process being carried out in the presence of a lipase.

Abstract: A process for enriching and separating polyunsaturated fatty acid (PUFA) acyl groups in a fatty acid mixture, which mixture contains other non-PUFA fatty acid acyl groups, is disclosed.

Abstract: The present invention is concerned with acyl ribonucleosides and with acyl deoxyribonucleosides. It is furthermore concerned with an enzymatic process for the manufacture of acyl ribonucleosides and of acyl deoxyribonucleosides. It is furthermore concerned with the use of acyl ribonucleosides and of acyl deoxyribonucleosides for cosmetic and for pharmaceutical purposes and with their use as a food supplement for humans or animals. It is furthermore concerned with compositions containing acyl ribonucleosides and acyl deoxyribonucleosides, whereby these compositions are suitable for cosmetic or for pharmaceutical purposes or as food supplement.

Abstract: The disclosed invention provides a process for obtaining fatty acid alkyl esters, rosin acids and sterols from crude tall oil (CTO), characterised in that the CTO is subjected to the following steps: (a) reacting the free fatty acids present in the CTO with lower alcohols; (b) separating the fatty acid lower alkyl esters thus obtained from the remaining CTO to produce a first stream of fatty acid esters; (c) esterifying the sterols in the remaining CTO with boric acid; (d) separating the remaining rosin acids from the sterol borates previously obtained to produce a second stream of rosin acids; and (e) converting said sterol borates into the free sterols to produce a third stream of free sterols.

Abstract: The disclosed invention refers to a process for obtaining fatty acid alkyl esters, rosin acids and sterols from crude tall oil (CTO), which is characterised by the following steps: (a) reacting the free fatty acids present in the CTO with lower alcohols; (b) esterifying the sterols in the CTO with boric acid or transesterifying the sterols with a catalyst; (c) separating the fatty acid lower alkyl esters and rosin acids from the remaining sterol borate esters or sterol esters of fatty acids to produce a stream of sterol esters; (d) separating the fatty acid alkyl esters from the rosin acids to produce a first stream of fatty acid alky esters and a second stream of rosin acids; and (e) converting the sterol esters into the free sterols to produce a third stream of free sterols.

Abstract: The invention relates to a method for production of a wash-resistant bond between a film on basis of copolyetherester waterproof and permeable to water vapor and at least one substrate on basis of polyester which is a woven or knitted fabric to achieve a pure bonded fabric having good wash resistance at 60° C., wherein said film on basis of copolyetherester which is waterproof and permeable to water vapor is manufactured with at least one film of a hot-melt adhesive on basis of a hydrophilic copolyetherester to a laminate previously before being bonded to said substrate by means of a hot-melt adhesive on basis of copolyester.