Abstract: The invention relates to a device for inserting sheets into an envelope, comprising a holding device (11) for holding the envelope, transport means (15) for feeding the sheets to be inserted to the holding device (11), a feed device (7, 8, 9) for feeding the envelope to the holding device (11), along a feed direction, and a removal device (8, 22) for removing the filled envelope from the holding device (11), along a removal direction. The invention is characterized in that the feed device (7, 8, 9) and the removal device (8, 22) are disposed relative to the holding device (11) in such a manner that a first angle between the feed device and a main surface of the holding device (11) and a second angle between the removal direction and the main surface of the holding device (11) are predetermined in a fixed manner and are different from each other. The invention allows to simplify the construction of the device, thereby reducing its technical complexity and failure proneness.

Abstract: An apparatus for processing envelopes. A support plates and a pressure sensing lever support a stack of envelopes in a generally upright orientation. The pressure sensing lever pivots in accordance with pressure exerted by the stack of envelopes. A feeding apparatus is operatively coupled to a sensor such that pivotal movement of the pressure sensing lever is detected by the sensor and the feeding apparatus changes the pressure exerted against the stack of envelopes.

Abstract: An apparatus for conveying envelopes traveling in a travel direction in a generally upright orientation. The apparatus includes a first pair of conveyor assemblies disposed opposite one another and configured to engage lateral edges of the envelopes, and configured to move the envelopes in the travel direction. The apparatus includes a second pair of conveyor assemblies disposed opposite one another and positioned downstream of the first pair of conveyor assemblies in the travel direction, with the second pair of conveyor assemblies being configured to move the envelopes in the travel direction independently of the first pair of conveyor assemblies.

Abstract: An apparatus for inserting a paper or film object or a stack of such objects into an envelope. A feeding apparatus moves the object toward an insertion station and a vacuum drum has a surface adapted to engage and move the envelope toward the insertion station. A ramp element is coupled to the vacuum drum and is adapted to support a leading portion of the envelope as the envelope moves With the vacuum drum.

Abstract: An apparatus transports a discrete paper or film object in a machine direction for insertion into an envelope. A guide assembly of the apparatus includes opposed first and second channels facing one another for guiding the object in the machine direction, with the channels extending upwardly to thereby define an uphill path of travel for the object. A drive apparatus includes engaging elements for moving the object along the first and second channels. At least one support element holds the object against the guide assembly.

Abstract: An apparatus for processing envelopes. A support plates and a pressure sensing lever support a stack of envelopes in a generally upright orientation. The pressure sensing lever pivots in accordance with pressure exerted by the stack of envelopes. A feeding apparatus is operatively coupled to a sensor such that pivotal movement of the pressure sensing lever is detected by the sensor and the feeding apparatus changes the pressure exerted against the stack of envelopes.

Abstract: Guiding and cutting apparatus for use in a paper converting and sheet inserting apparatus. Guiding apparatus includes first and second rollers for engaging lateral edges of a web and a driving apparatus configured to permit the rollers to rotate at different surface speeds relative to one another. Cutting apparatus includes an angled blade for transversely cutting each side-by-side portion of a slit web into discrete sheets. Two side-by-side sheets are cut from respective web portions separately in time. Method, blade apparatus, web brake and slitter apparatus are disclosed.

Abstract: Apparatus is provided for transporting a paper or film discrete object in a machine direction. A top engaging portion contacts a first side of the object and a bottom engaging portion contacts a second side of the object opposite the first side and respectively cooperates with the top engaging portion to grip and move the object in the machine direction. At least one of the top engaging portion or the bottom engaging portion includes a plurality of deflectable elements for engaging the object.

Abstract: Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavir. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.

Abstract: Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavir. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.

Abstract: Activated haptens useful for generating immunogen to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavir. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.

Abstract: A stitching apparatus with thread tension control is provided. Tension in a thread is monitored during stitching apparatus operations, and remedial action is taken in response to the detection of an anomaly in the thread tension profile. The remedial action can include altering a feed rate of the thread in order to adjust the thread tension, and/or repeating a previous operation. Anomaly detection can be performed with respect to stitching or sewing operations, and also with respect to trim operations performed in connection with moving between elements and/or thread color changes.

Abstract: A system and method for generating a work order instructions is described. In one embodiment an order from a customer is received, which includes information for a desired end product and the information is converted into machine-readable work order instructions, which includes instructions to alter goods in accordance with the desired end product. In addition, the machine readable work order instructions are sent via a network to a value-adding business and loaded into a machine at the value-adding business, which is configured to alter the goods in accordance with the instructions for altering the goods.

Abstract: Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavir. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.

Abstract: Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavir. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.

Abstract: Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavor. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.

Abstract: Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavir. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.

Abstract: A system and method for assisting a plurality of separate businesses is described. In one variation, the method includes establishing a plurality of customized Internet home pages corresponding to the plurality of separate value-adding businesses, and receiving a purchase order via at least one of the plurality of customized Internet home pages. Based on the purchase order, information is sent to a value-adding business and a request for unfinished goods is sent to at least one supplier of unfinished goods. The supplier provides the unfinished goods to the value-adding business to enable the business to alter the unfinished goods in accordance with the purchase order information.

Abstract: Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for HIV protease inhibitors. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group common to all HIV protease inhibitors, e.g., saquinavir, nelfinavir, indinavir, amprenavir, ritonavir, lopinavir, and atazanavir.

Abstract: The invention relates to a device for inserting sheets into an envelope, comprising a holding device (11) for holding the envelope, transport means (15) for feeding the sheets to be inserted to the holding device (11), a feed device (7, 8, 9) for feeding the envelope to the holding device (11), along a feed direction, and a removal device (8, 22) for removing the filled envelope from the holding device (11), along a removal direction. The invention is characterized in that the feed device (7, 8, 9) and the removal device (8, 22) are disposed relative to the holding device (11) in such a manner that a first angle between the feed device and a main surface of the holding device (11) and a second angle between the removal direction and the main surface of the holding device (11) are predetermined in a fixed manner and are different from each other. The invention allows to simplify the construction of the device, thereby reducing its technical complexity and failure proneness.