Patents by Inventor Peter Kleinwächter

Peter Kleinwächter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Branched building units for synthesizing cyclic peptides
    Patent number: 6184345
    Abstract: The present invention relates to building units suitable for the synthesis of backbone cyclized peptides. The building units of this invention have structures of Formula (I): X—AAm—U—AAp—Y  (I) wherein AAm and AAp are residues of natural or synthetic amino acids and U is C&agr;ON[(CH2)n+1W] or &PSgr;(C&agr;H2N)[CO(CH2)qW], in which C&agr; is a carbon atom and is the &agr; carbon of AAm if m>0. W is NH—X or COY, and X is H, Boc, Z, Fmoc, or Alloc while Y is the hydroxyl group of a carboxylic acid moiety or a carboxylic acid protecting group. The letter m refers to an integer from 0 to 10; n is a number from 0 to 6; p is a number from 1 to 10; and q is a number from 1 to 6. The present invention is also directed to methods of synthesizing building units of Formula (I) via different routes.
    Type: Grant
    Filed: February 8, 1999
    Date of Patent: February 6, 2001
    Assignee: Peptor Limited
    Inventors: Siegmund Reissmann, Bettina Müller, Peter Kleinwächter, Diana Besser