Patents by Inventor Peter Kolkhof

Peter Kolkhof has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted Arylimidazolone and Triazolone as Inhibitors of Vasopressin Receptors
    Publication number: 20090312381
    Abstract: The present application relates to novel, substituted 4-arylimidazol-2-ones and 5-aryl-1,2,4-triazolones, processes for the production thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases and the use thereof for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
    Type: Application
    Filed: May 21, 2007
    Publication date: December 17, 2009
    Applicant: BAYER HEALTHCARE AG
    Inventors: Heinrich Meier, Eckhard Bender, Ulf Brüggemeier, Ingo Flamme, Dagmar Karthaus, Peter Kolkhof, Daniel Meibom, Dirk Schneider, Verena Voehringer, Chantal Fürstner, Jörg Keldenich, Dieter Lang, Elisabeth Pook, Carsten Schmeck
  • Human Marker Genes and Agents for Diagnosis, Treatment and Prophylaxis of Cardiovascular Disorders and Artherosclerosis
    Publication number: 20090214477
    Abstract: The invention relates to novel targets in the screening for compounds useful in the treatment and/or prophylaxis of a disease selected from the group comprising cardiovascular diseases, disorders of lipid metabolism or atherosclerosis. The invention relates to novel compounds for use as a medicament for diseases or conditions involving a disease selected from the group comprising cardiovascular diseases, disorders of lipid metabolism or atherosclerosis. The invention especially relates to antagonists and expression-inhibitory compounds that target G-protein coupled receptors (GPCRs), kinases and proteases, and to methods for identifying such compounds. The invention further relates to methods for identifying these antagonists and expression-inhibitory compounds, and methods for diagnosing a disease selected from the group comprising cardiovascular diseases, disorders of lipid metabolism or atherosclerosis or a susceptibility to such a condition.
    Type: Application
    Filed: April 8, 2006
    Publication date: August 27, 2009
    Applicant: Cenix BioScience GmbH
    Inventors: Ulrich Betz, Donatella D'Urso, Peter Kolkhof, Michael Seewald, Jochen Strayle, Anne Plötner, Michael Hannus
  • 4-Chromenonyl-1,4-dihydropyridinecarbonitriles and the use thereof
    Publication number: 20090214675
    Abstract: The present application relates to novel 4-chromenonyl-1,4-dihydropyridinecarbonitriles, processes for their preparation, pharmaceutical compositions containing them, and their use for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.
    Type: Application
    Filed: July 14, 2006
    Publication date: August 27, 2009
    Applicant: Bayer HealthCare AG
    Inventors: Alexander Kuhl, Peter Kolkhof, Heike Heckroth, Karl-Heinz Schlemmer, Ingo Flamme, Santiago Figueroa Perez, Heike Gielen-Haertwig, Rolf Grosser, Jens-Kerim Ergüden, Dieter Lang
  • Tricyclic benzazepine derivatives and their use
    Publication number: 20090215743
    Abstract: The present application relates to novel tricyclic benzazepine derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, especially of dyslipidaemias, arteriosclerosis, restenosis and ischaemias.
    Type: Application
    Filed: December 31, 2004
    Publication date: August 27, 2009
    Applicant: Bayer HealthCare AG
    Inventors: Elisabeth Woltering, Michael Härter, Timo Flessner, Mario Jeske, Nils Griebenow, Frank Süssmeier, Hilmar Bischoff, Martin Raabe, Anja Buchmüller, Peter Kolkhof, Peter Ellinghaus, Olaf Weber
  • Isophthalic acid derivatives
    Patent number: 7498460
    Abstract: The present invention relates to isophthalic acid derivatives, to a process for their preparation and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular of cardiovascular disorders.
    Type: Grant
    Filed: November 28, 2003
    Date of Patent: March 3, 2009
    Assignee: Bayer Healthcare AG
    Inventors: Michael Härter, Jens Ergüden, Frank Wunder, Hanna Tinel, Johannes Köbberling, Eva-Maria Becker, Klaus Münter, Karl-Heinz Schlemmer, Raimund Kast, Peter Kolkhof, Gunter Karig, Lars Bärfacker, Walter Hübsch, Joachim Schuhmacher, Susanne Zuleger, Arnel Concepcion, Haruka Shimizu
  • Tetrahydrobenzo(D)Azepin-2-One Derivatives and the Use Thereof for Treating Cardiovascular Diseases
    Publication number: 20070287698
    Abstract: The present application relates to novel tetrahydrobenzo[d]azepin-2-one derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, especially of dyslipidaemias, arteriosclerosis, restenosis and ischaemias.
    Type: Application
    Filed: February 1, 2005
    Publication date: December 13, 2007
    Applicant: Bayer HealthCare AG
    Inventors: Nils Griebenow, Timo Flessner, Michael Harter, Martin Raabe, Anja Buchmuller, Hilmar Bischoff, Peter Ellinghaus, Peter Kolkhof
  • Quinoxalinones and their use especially in the treatment of cardiovascular diseases
    Publication number: 20060247244
    Abstract: The invention relates to quinoxalinones and to methods for producing the same as well as the use thereof for preparing drugs for the treatment and/or prophylaxis of diseases, especially of cardiovascular diseases.
    Type: Application
    Filed: January 27, 2003
    Publication date: November 2, 2006
    Applicant: BAYER HEALTHCARE AG
    Inventors: Jens-Kerim Ergüden, Peter Kolkhof, Julio Castro-Palomino, Alexander Kuhl, Raimund Kast, Johannes-Peter Stasch, Hanna Tinel, Klaus Münter, Klemens Lustig, Josef Pernerstorfer, Martin Bechem, Jörg Hüser
  • Isophtalic acid derivatives
    Publication number: 20060154912
    Abstract: The present invention relates to isophthalic acid derivatives, to a process for their preparation and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular of cardiovascular disorders.
    Type: Application
    Filed: November 28, 2003
    Publication date: July 13, 2006
    Inventors: Michael Harter, Jens Erguden, Frank Wunder, Hanna Tinel, Johannes Kobberling, Eva-Maria Becker, Klaus Munter, Karl-Heinz Schlemmer, Raimund Kast, Peter Kolkhof, Gunter Karig, Lars Barfacker, Walter Hubsch, Joachim Schuhmacher, Susanne Zuleger, Arnel Concepcion, Haruka Shimizu
  • Pyrimido[1,2-a]indoles
    Patent number: 6114341
    Abstract: The pyrimido[1,2-a]indoles according to the invention are prepared by reacting appropriately substituted phenylacetic acid derivatives with phenylglycinols. The pyrimido[1,2-a]indoles can be used as active compounds in medicaments, in particular in medicaments with antiatherosclerotic activity.
    Type: Grant
    Filed: March 31, 1997
    Date of Patent: September 5, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich Muller, Peter Eckenberg, Rudi Grutzmann, Hilmar Bischoff, Dirk Denzer, Stefan Wohlfeil, Stefan Lohmer, Ulrich Nielsch, Peter Kolkhof