Abstract: Dehydroabietic acid derivatives according to Formula Ia or Formula Ib and all stereoisomers thereof, having a linker chain A of 1 to 10 atoms selected from carbon, nitrogen and oxygen to a group X capable of being negatively charged at a physiological pH and covalently attached to the linker chain A, selected from carboxyl, sulfate, sulfonate and phosphate groups.

Abstract: The present invention relates to derivatives of dehydroabietic acid useful in treatment of cardiac arrhythmia or a hyperexcitablity disease, such as epilepsy or pain, by extracellularly acting on the voltage sensitive domain (VSD) to open at least one member of the family of voltage-gated Kv (potassium) channels.

Abstract: The present invention relates to oligothiophene derivatives binding specifically to neural stem cells and neural cancer stem cells. More specifically, the invention relates to methods for detecting neural stem cells or neural cancer stem cells using said oligothiophene derivatives in a biological sample, as well as uses and kits relating thereto.

Abstract: A compound is provided of the formula wherein each u is independently selected from 0 and 1; each R2 and R4 is independently selected from carboxy, carboxyalkyl, alkoxycarbonylalkyl, aminoalkyl, (amino)(carboxy)alkyl and (amino)(carboxy)alkoxy; or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure relates to a device comprising a conductive substrate surface (19), at least one layer of a conductive polymer (14) deposited on the surface (19), a first electrolyte (13) arranged in contact with the conductive polymer layer, and a counter electrode (11), arranged in contact with the first electrolyte (13), such that a potential difference can be applied between the conductive substrate (15) and the counter electrode (11). The conductive polymer (14), in a first state, before applying the potential difference, exhibits a first adhesive capacity, wherein the conductive polymer layer (14) is substantially attached to the conductive substrate surface (19). In a second state, subsequent to application of the potential difference, the conductive polymer (14), exhibits a second adhesive capacity, such that at least a portion of the conductive polymer layer (14) is substantially released from the conductive substrate surface (19).

Abstract: The present invention relates to oligothiophene derivatives binding specifically to neural stem cells and neural cancer stem cells. More specifically, the invention relates to methods for detecting neural stem cells or neural cancer stem cells using said oligothiophene derivatives in a biological sample, as well as uses and kits relating thereto.

Abstract: The present invention relates to novel substituted thiophene derivatives useful in therapy of diseases related to misfolded and aggregated proteins.