Patents by Inventor Peter Kristoffersen

Peter Kristoffersen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7595186
    Abstract: Method of conditionally controlling the survivability of a recombinant cell population and of containing such cells to an environment or containing replicons to a host cell is based on the use of proteic killer systems including E. coli relBE locus and similar systems found in Gram-negative and Gram-positive bacteria and Archae. Such systems are generally based on a cytotoxin polypeptide and an antitoxin or antidote polypeptide that in contrast to the cytotoxin is degradable by proteases. The recombinant cells are useful as vaccines, pollutant degrading organisms or as biological pest control organism e.g. expressing B. thuringiensis crystalline proteins.
    Type: Grant
    Filed: August 10, 2007
    Date of Patent: September 29, 2009
    Assignee: Université Libre de Bruxelles
    Inventors: Kenn Gerdes, Marie Mikkelsen, Hugo Gronlund, Kim Pedersen, Peter Kristoffersen
  • Patent number: 7595185
    Abstract: Method of conditionally controlling the survivability of a recombinant cell population and of containing such cells to an environment or containing replicons to a host cell is based on the use of proteic killer systems including the E. coli relBE locus and similar systems found in Gram-negative and Gram-positive bacteria and Archae. Such system are generally based on a cytotoxin polypeptide and an antitoxin or antidote polypeptide that in contrast to the cytotoxin is degradable by proteases. The recombinant cells are useful as vaccines, pollutant degrading organisms or as biological pest control organisms e.g. expressing B. thuringiensis crystalline proteins.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: September 29, 2009
    Assignee: Université Libre de Bruxelles
    Inventors: Kenn Gerdes, Marie Mikkelsen, Hugo Gronlund, Kim Pedersen, Peter Kristoffersen
  • Publication number: 20090028842
    Abstract: The present invention relates to cytosine deaminase protein and cDNA from various species of the yeast genus Dekkera/Brettanomyces. Compared to yeast cytosine deaminase the novel cytosine deaminases are more efficient and have a higher stability. The invention also relates to the field of suicide gene therapy based on activation of a non-toxic prodrug, 5-fluorocytosine to a toxic drug 5-fluorouracil based on the enzymatic activity of novel cytosine deaminses. Finally the invention provides use of 5-fluorocytosine for controlling the growth of Dekkera/Brettanomyces yeast.
    Type: Application
    Filed: September 29, 2006
    Publication date: January 29, 2009
    Applicant: ZGene A/S
    Inventors: Zoran Gojkovic, Peter Kristoffersen
  • Publication number: 20080206840
    Abstract: Method of conditionally controlling the survivability of a recombinant cell population and of containing such cells to an environment or containing replicons to a host cell is based on the use of proteic killer systems including E. coli relBE locus and similar systems found in Gram-negative and Gram-positive bacteria and Archae. Such systems are generally based on a cytotoxin polypeptide and an antitoxin or antidote polypeptide that in contrast to the cytotoxin is degradable by proteases. The recombinant cells are useful as vaccines, pollutant degrading organisms or as biological pest control organism e.g. expressing B. thuringiensis crystalline proteins.
    Type: Application
    Filed: August 10, 2007
    Publication date: August 28, 2008
    Inventors: Kenn Gerdes, Marie Mikkelsen, Hugo Gronlund, Kim Pedersen, Peter Kristoffersen
  • Publication number: 20080182327
    Abstract: Method of conditionally controlling the survivability of a recombinant cell population and of containing such cells to an environment or containing replicons to a host cell is based on the use of proteic killer systems including the E. coli relBE locus and similar systems found in Gram-negative and Gram-positive bacteria and Archae. Such system are generally based on a cytotoxin polypeptide and an antitoxin or antidote polypeptide that in contrast to the cytotoxin is degradable by proteases. The recombinant cells are useful as vaccines, pollutant degrading organisms or as biological pest control organisms e.g. expressing B. thuringiensis crystalline proteins.
    Type: Application
    Filed: November 10, 2006
    Publication date: July 31, 2008
    Applicant: Universite Libre Bruxelles
    Inventors: Kenn Gerdes, Marie Mikkelsen, Hugo Gronlund, Kim Pedersen, Peter Kristoffersen