Patents by Inventor Peter Kuehl

Peter Kuehl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for treating spinal muscular atrophy
    Patent number: 11938136
    Abstract: The present invention provides pharmaceutical compositions comprising a compound of formula (I) wherein A, R1, R2 and R3 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the pharmaceutical compositions comprising a compound of formula (I) and their use as medicaments.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: March 26, 2024
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jochem Alsenz, Olaf Grassmann, Peter Kuehl, Friedrich Metzger, Kathleen Dorothy Mccarthy, Eduardo Paulo Morawski Vianna, Marvin Lloyd Woodhouse
  • NEW FORMS OF PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES, ITS FORMULATION AND ITS PROCESS OF MAKING
    Publication number: 20210403487
    Abstract: The present invention relates to a process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one useful as pharmaceutically active compounds.
    Type: Application
    Filed: April 16, 2021
    Publication date: December 30, 2021
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Roland MEIER, Urs SCHWITTER, Anne DE PAEPE, Peter KUEHL, Juergen THUN, Frank STOWASSER
  • COMPOSITIONS FOR TREATING SPINAL MUSCULAR ATROPHY
    Publication number: 20200323856
    Abstract: The present invention provides pharmaceutical compositions comprising a compound of formula (I) wherein A, R1, R2 and R3 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the pharmaceutical compositions comprising a compound of formula (I) and their use as medicaments.
    Type: Application
    Filed: November 15, 2019
    Publication date: October 15, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jochem ALSENZ, Olaf GRASSMANN, Peter KUEHL, Friedrich METZGER, Kathleen Dorothy MCCARTHY, Eduardo Paulo Morawski VIANNA, Marvin Lloyd WOODHOUSE
  • COMPOSITIONS FOR TREATING SPINAL MUSCULAR ATROPHY
    Publication number: 20180289712
    Abstract: The present invention provides pharmaceutical compositions comprising a compound of formula (I) wherein A, R1, R2 and R3 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the pharmaceutical compositions comprising a compound of formula (I) and their use as medicaments.
    Type: Application
    Filed: April 17, 2018
    Publication date: October 11, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jochem Alsenz, Olaf Grassmann, Peter Kuehl, Friedrich Metzger, Kathleen Dorothy McCarthy, Eduardo Paulo Morawski Vianna, Marvin Lloyd Woodhouse
  • PHARMACEUTICAL COMPOSITIONS COMPRISING 40-O-(2-HYDROXY)ETHYL-RAPAMYCIN
    Publication number: 20180214424
    Abstract: The invention relates to extended release pharmaceutical formulations in form of multiparticulates comprising 40-O-(2-hydroxy)ethyl-rapamycin, to dosage forms which comprise said pharmaceutical formulations, to methods of preparing said pharmaceutical formulations and said dosage forms, to uses of said pharmaceutical formulations and said dosage for the manufacture of a medicament for the treatment or prevention of diseases or conditions responsive to inhibition of mTOR signaling pathway, such as for instance proliferative diseases or immunosuppression.
    Type: Application
    Filed: January 24, 2018
    Publication date: August 2, 2018
    Inventors: Anke Diederich, Kurt LIECHTI, Peter KUEHL, Wing CHEUNG
  • PHARMACEUTICAL COMPOSITIONS COMPRISING 40 - O - ( 2 - HYDROXY) ETHYL - RAPAMYCIN
    Publication number: 20170049754
    Abstract: The invention relates to extended release pharmaceutical formulations in form of multiparticulates comprising 40-O-(2-hydroxy)ethyl-rapamycin, to dosage forms which comprise said pharmaceutical formulations, to methods of preparing said pharmaceutical formulations and said dosage forms, to uses of said pharmaceutical formulations and said dosage for the manufacture of a medicament for the treatment or prevention of diseases or conditions responsive to inhibition of mTOR signaling pathway, such as for instance proliferative diseases or immunosuppression.
    Type: Application
    Filed: November 7, 2016
    Publication date: February 23, 2017
    Inventors: Anke DIEDERICH, Kurt LIECHTI, Peter KUEHL, Wing CHEUNG
  • PHARMACEUTICAL COMPOSITIONS COMPRISING 40 - O - ( 2 - HYDROXY) ETHYL - RAPAMYCIN
    Publication number: 20140242162
    Abstract: The invention relates to extended release pharmaceutical formulations in form of multiparticulates comprising 40-O-(2-hydroxy)ethyl-rapamycin, to dosage forms which comprise said pharmaceutical formulations, to methods of preparing said pharmaceutical formulations and said dosage forms, to uses of said pharmaceutical formulations and said dosage for the manufacture of a medicament for the treatment or prevention of diseases or conditions responsive to inhibition of mTOR signaling pathway, such as for instance proliferative diseases or immunosuppression.
    Type: Application
    Filed: October 3, 2012
    Publication date: August 28, 2014
    Inventors: Anke Diederich, Kurt Liechti, Peter Kuehl, Wing Cheung