Abstract: Medical devices and systems for treating a stricture, for example along the biliary and/or pancreatic tract, are disclosed. An example system may include a guidewire having a distal end and defining a lumen. A stiffening rod may be slidably disposed within the lumen. The stiffening rod may have a distal end and a distal end region disposed adjacent to the distal end. The stiffening rod may be configured to shift between a first position where the distal end of the stiffening rod is disposed proximally of the distal end of the guidewire and a second position where the distal end of the stiffening rod is disposed distally of the distal end of the guidewire.

Abstract: Embodiments of the disclosure include methods and systems for attaching an articulation section. In an embodiment, a medical instrument includes a first tubular member including a first end. The medical instrument also includes a second tubular member including a first end. The second tubular member includes a plurality of layers including an inner layer and a first layer including a fluorinated material. The inner layer includes a first section disposed under the first layer and a second section extending out from under the first layer. A portion of the first tubular member overlaps and is bonded to at least a portion of the second section of the inner layer of the second tubular member.

Abstract: Systems and methods for treating a stricture, for example along the biliary and/or pancreatic tract, are disclosed. An example system may include a handle having a base having a distal end region and a proximal end region. A length adjustment member may be coupled to the handle. A length actuator may be coupled to the distal end region of the handle. A catheter shaft may be coupled to the handle. A steering mechanism may be coupled to the handle. The steering mechanism may include an elongate steering member having a first end region coupled to the handle, a first body region extending along the catheter shaft, a loop region extending about the catheter shaft, a second body region extending along the catheter shaft, and a second end region coupled to the handle.

Abstract: A medical system includes a medical device having a handle, a shaft, an actuation member, and medical system also includes a cartridge and a plunger. The handle includes an actuator movable relative to the handle, and the actuator is coupled to a distal end of the shaft via the actuation member. The cartridge contains a treatment agent, and the cartridge is couplable to the distal end of the shaft. The plunger is movable relative to the cartridge. Movement of the actuator controls movement of the actuation member. Movement of the actuation member controls movement of either the plunger or the cartridge to control a delivery of the treatment agent from the cartridge.

Abstract: An elongate medical device is adapted to provide adjustable flexibility. The elongate medical device includes an inner coil having one or more inner coil filars extending in a first direction, and an outer coil having one or more outer filars extending in a second direction. A hypotube extends proximally from the inner coil and the outer coil. A cable extends through the inner coil and through the hypotube, where a distal end of the cable, a distal end of the inner coil and a distal end of the outer coil are all secured together at a distal end of the elongate medical device, such that applying a tensile force to the cable, relative to the hypotube, causes the inner coil and outer coil in combination to increase in stiffness.

Abstract: A method for performing a medical procedure may comprise advancing a first device through a first body lumen. A distal portion of the first device may include a magnet. The method may further comprise advancing a second device through a second body lumen. The second device may include a magnetic field sensor. The method may further comprise receiving a signal from the magnetic field sensor. The signal may be indicative of a magnetic field measured by the magnetic field sensor. The method may further comprise, if the received signal matches a magnetic field of the magnet, identifying a position of the magnet.

Abstract: An implantable device configured to be deployed at a deployment site such as across a body passage. The implantable device has features enhancing the resistance of at least a portion of the implantable device to migration from the deployment site. The implantable device may have surfaces contacting tissue at the deployment site which are configured to promote tissue ingrowth with respect to the implantable device. Surfaces of the implantable device not contacting tissue may be enlarged and coated with a coating material increasing the strength of the coated portions of the implantable device to resist migration of the implantable device with respect to the deployment site.

Abstract: The disclosure relates generally to devices and methods for treating a tissue defect, for example, by suturing. In some embodiments, a suturing device may include an elongate member having a working channel, a suture channel, and a suture arm extending from the elongate member. The suturing device may further include a needle passer located within the working channel, the needle passer operable to deliver a needle between the elongate member and a distal end of the suture arm for suturing a target tissue, and a suture extending through the suture channel, wherein the suture is coupled to the needle. The suturing device may further include a plurality of imaging devices, wherein a first imaging device is positioned along a distal face of the elongate member, and wherein a second imaging device is positioned along the suture arm.

Abstract: A method for performing a medical procedure may comprise advancing a first device through a first body lumen. A distal portion of the first device may include a magnet. The method may further comprise advancing a second device through a second body lumen. The second device may include a magnetic field sensor. The method may further comprise_receiving a signal from the magnetic field sensor. The signal may be indicative of a magnetic field measured by the magnetic field sensor. The method may further comprise, if the received signal matches a magnetic field of the magnet, identifying a position of the magnet.

Abstract: The present disclosure relates to medical devices that that include the following: a flexible elongate tube having a proximal end and a distal end configured to be directed toward an opening of a body lumen; a first lumen extending from the distal end of the tube proximally along the tube and having a fluid connection for a fluid source at its proximal end; a second lumen extending from the distal end of the tube proximally along the tube, the second lumen configured to accept a guidewire extending along the second lumen; and a wire filament extending along the elongate tube, a distal end of the filament connected to the distal end of the elongate tube, a proximal portion of the wire extending at least partially along the elongate tube, and a distal portion of the wire extending external to the elongate tube.

Abstract: A device for treating tissue includes a catheter including an elongated body extending from a proximal end to a distal end and including a lumen extending therethrough, a distal tip connected to the distal end of the elongated body and including a first electrode and a second electrode extending thereabout, the first electrode extending to a distal opening of the lumen and a first needle extending longitudinally from a proximal end to a distal end, the first needle slidably received within the lumen of the catheter to be moved between a retracted bipolar configuration, in which the distal end of the needle is proximal the distal opening of the catheter, and an extended monopolar configuration, in which the distal end of the first needle extends distally past the distal opening of the catheter so that the first needle contacts the first electrode and is configured to cut tissue.

Abstract: The present disclosure relates generally to devices and methods for treating a tissue defect, for example, by suturing. In some embodiments, a suturing device may include an elongate member having a working channel, a suture channel, and a suture arm extending from the elongate member. The suturing device may further include a needle passer located within the working channel, the needle passer operable to deliver a needle between the elongate member and a distal end of the suture arm for suturing a target tissue, and a suture extending through the suture channel, wherein the suture is coupled to the needle. The suturing device may further include a plurality of imaging devices, wherein a first imaging device is positioned along a distal face of the elongate member, and wherein a second imaging device is positioned along the suture arm.

Abstract: Sphincterotomes and methods for making and using sphincterotomes are disclosed. An example sphincterotome may include an elongate shaft having an outer surface and a distal end region. The sphincterotome may also include a sphincterotome wire assembly having a distal end coupled to the distal end region of the elongate shaft and a body portion extending along the outer surface of the elongate shaft. The sphincterotome wire assembly may be designed to shift the distal end region of the elongate shaft between a first configuration and a curved configuration. The body portion of the sphincterotome wire assembly may include a cutting region and a nonconductive region.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to single-use endoscopic medical devices with integrated and purpose-built functionality.

Abstract: The present disclosure relates generally to the field of minimally invasive catheter-based devices and procedures for the removal of necrotic debris. In particular, the present disclosure relates to systems and methods for the removal of necrotic debris from within a walled off necrosis without disrupting or damaging the tissue wall of the necrotic pocket.

Abstract: A device for treating tissue includes a catheter including an elongated body extending from a proximal end to a distal end and including a lumen extending therethrough, a distal tip connected to the distal end of the elongated body and including a first electrode and a second electrode extending thereabout, the first electrode extending to a distal opening of the lumen and a first needle extending longitudinally from a proximal end to a distal end, the first needle slidably received within the lumen of the catheter to be moved between a retracted bipolar configuration, in which the distal end of the needle is proximal the distal opening of the catheter, and an extended monopolar configuration, in which the distal end of the first needle extends distally past the distal opening of the catheter so that the first needle contacts the first electrode and is configured to cut tissue.

Abstract: Sphincterotomes and methods for making and using sphincterotomes are disclosed. An example sphincterotome may include an elongate shaft having an outer surface and a distal end region. The sphincterotome may also include a sphincterotome wire assembly having a distal end coupled to the distal end region of the elongate shaft and a body portion extending along the outer surface of the elongate shaft. The sphincterotome wire assembly may be designed to shift the distal end region of the elongate shaft between a first configuration and a curved configuration. The body portion of the sphincterotome wire assembly may include a cutting region and a non-conductive region.

Abstract: A mesh element having a mesh gauge selected to control flow of materials therethrough. The mesh element is implantable into an anatomical structure upstream of a body passage or within a body passage to control flow of materials through the body passage. The mesh element may be coupled to a support structure to facilitate anchoring of the mesh element in place relative to the body passage. The support structure may have a lumen defined therethrough to allow flow of materials through the body passage, with the mesh element regulating the flow of materials into the lumen. The mesh element alternatively may be directly coupled to an anatomical structure upstream of a body passage to regulate or determine flow of materials through the body passage.

Abstract: A medical device that comprises a rim defining a loop in a plane and defining a width measured perpendicular to the plane, at least one wire coupled to a distal end of the rim and extending proximally from the distal end out of the plane to a proximal end of the rim, the at least one wire having a cross-sectional dimension measured perpendicular to a longitudinal axis of the at least one wire, the cross-sectional dimension being smaller than the width of the rim, and a sheath configured to cover at least a portion of the rim and a portion of the at least one ware.

Abstract: The present disclosure relates generally to the field of devices and procedures for placement of a medical device between adjacent tissue structures. In particular, the present disclosure relates to systems and methods for percutaneous placement of a drainage stent between the gallbladder and gastric lumen (e.g., cholecystogastrostomy), or gallbladder and duodenum (cholecystoduodenostomy).