Patents by Inventor Peter L. Devine

Peter L. Devine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Minactivin compositions and antibodies to minactivin
    Patent number: 5426044
    Abstract: A novel human protein, minactivin, can be produced by recombinant DNA technology, Biologically active native minactivin, peptides derived from minactivin, and their amino acid sequences can also be purified.
    Type: Grant
    Filed: April 30, 1991
    Date of Patent: June 20, 1995
    Assignees: Biotechnology Australia, Pty., Ltd., Australian National University
    Inventors: Toni M. Antalis, Thomas M. Barnes, Michelle A. Clark, Peter L. Devine, Neil H. Goss, Philip R. Lehrbach
  • Human PAI-2
    Patent number: 5422090
    Abstract: Minactivin (also known as Plasminogen Activator Inhibitor-2 [PAI-2]), a protein inactivator of urokinase-type plasminogen activator, has been shown to be a natural inactivator of this plasminogen activator which is associated with invasive tumors, and is therefore indicated as a crucial element in the body's normal defense against tumor invasion and metastasis. It may be produced by the cultivation of minactivin-producing cells in vitro, and recovery of the cell culture supernatant. By controlling the culture conditions, the protein minactivin may be produced in a partially purified form which may be used for diagnosis and treatment of tumors. The specification discloses purification of biologically active native minactivin, as well as peptides derived from minactivin and their amino acid sequences.
    Type: Grant
    Filed: July 15, 1992
    Date of Patent: June 6, 1995
    Assignees: Biotechnology Australia, Pty., Ltd., Australian National University
    Inventors: Ross W. Stephens, Jeffrey P. Golder, Toni M. Antalis, Thomas M. Barnes, Michell A. Clark, Peter L. Devine, Neil H. Goss, Philip R. Lehrbach