Patents by Inventor Peter Lachmann

Peter Lachmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210268076
    Abstract: Raising the level of Factor I above physiological levels can be used to treat diseases in which the underlying pathology is linked to overactivity of the C3b-feedback cycle and the generation and pro-inflammatory effects of iC3b. Methods, agents, and compositions for treatment of such diseases are described.
    Type: Application
    Filed: February 9, 2021
    Publication date: September 2, 2021
    Inventor: Peter Lachmann
  • Patent number: 10940186
    Abstract: Raising the level of Factor I above physiological levels can be used to treat diseases in which the underlying pathology is linked to overactivity of the C3b-feedback cycle and the generation and pro-inflammatory effects of iC3b. Methods, agents, and compositions for treatment of such diseases are described.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: March 9, 2021
    Assignee: CAMBRIDGE ENTERPRISE LIMITED
    Inventor: Peter Lachmann
  • Publication number: 20200147240
    Abstract: Methods of treatment of complement-mediated disorders, in particular disorders associated with over-activity of the complement C3b feedback cycle (for example, age-related macular degeneration (AMD)), using gene therapy is described. According to the methods, levels of complement Factor I are elevated by administration of a recombinant viral vector encoding Factor I such that a therapeutically effective amount of the encoded Factor I is expressed from the vector in the subject. Recombinant viral vectors encoding Factor I, recombinant virus particles encapsidating the vectors, and their use in the methods of treatment, is also described.
    Type: Application
    Filed: May 3, 2017
    Publication date: May 14, 2020
    Inventors: Peter Lachmann, Ian Alexander
  • Publication number: 20180021416
    Abstract: Raising the level of Factor I above physiological levels can be used to treat diseases in which the underlying pathology is linked to overactivity of the C3b-feedback cycle and the generation and pro-inflammatory effects of iC3b. Methods, agents, and compositions for treatment of such diseases are described.
    Type: Application
    Filed: September 29, 2017
    Publication date: January 25, 2018
    Applicant: CAMBRIDGE ENTERPRISE LIMITED
    Inventor: Peter Lachmann
  • Patent number: 9782460
    Abstract: Raising the level of Factor I above physiological levels can be used to treat diseases in which the underlying pathology is linked to overactivity of the C3b-feedback cycle and the generation and pro-inflammatory effects of iC3b. Methods, agents, and compositions for treatment of such diseases are described.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: October 10, 2017
    Assignee: CAMBRIDGE ENTERPRISE LIMITED
    Inventor: Peter Lachmann
  • Publication number: 20150374804
    Abstract: Raising the level of Factor I above physiological levels can be used to treat diseases in which the underlying pathology is linked to overactivity of the C3b-feedback cycle and the generation and pro-inflammatory effects of iC3b. Methods, agents, and compositions for treatment of such diseases are described.
    Type: Application
    Filed: June 29, 2015
    Publication date: December 31, 2015
    Inventor: Peter Lachmann
  • Patent number: 9066941
    Abstract: Rising the level of Factor I above physiological levels can be used to treat diseases in which the underlying pathology is linked to overactivity of the C3b-feedback cycle and the generation and pro-inflammatory effects of iC3b. Methods, agents, and compositions for treatment of such diseases are described.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: June 30, 2015
    Assignee: Cambridge Enterprise Limited
    Inventor: Peter Lachmann
  • Publication number: 20120087905
    Abstract: Raising the level of Factor I above physiological levels can be used to treat diseases in which the underlying pathology is linked to overactivity of the C3b-feedback cycle and the generation and pro-inflammatory effects of iC3b. Methods, agents, and compositions for treatment of such diseases are described.
    Type: Application
    Filed: March 12, 2010
    Publication date: April 12, 2012
    Applicant: CAMBRIDGE ENTERPRISE LIMITED
    Inventor: Peter Lachmann
  • Patent number: 4503971
    Abstract: A conveying plant in which a bucket-type conveying belt has along its opposite longitudinal edges, which are transversely spaced apart, successions of pairs of blocks which form guide rails for the conveyor. The blocks can clamp over steep stretches of the belt, respective traction ropes which are driven to relieve the belt.
    Type: Grant
    Filed: August 27, 1982
    Date of Patent: March 12, 1985
    Inventor: Hans-Peter Lachmann