Abstract: The present invention relates to a hypoallergenic molecule consisting of Bet v Ia or an allergen having at least 40% identity to Bet v Ia comprising mutations of at least four amino acid residues in the region of amino acids 100 to 125 of Bet v Ia or its corresponding region of the allergen having at least 40% identity to Bet v 1a.

Abstract: The present invention relates to a hypoallergenic molecule consisting of Bet v Ia or an allergen having at least 40% identity to Bet v Ia comprising mutations of at least four amino acid residues in the region of amino acids 100 to 125 of Bet v Ia or its corresponding region of the allergen having at least 40% identity to Bet v Ia.

Abstract: The present invention relates to a method for identifying a hypoallergenic derivative of a wild-type allergen comprising: determining the three-dimensional structure of a wild-type allergen; introducing at least one point mutation into said wild-type allergen, thereby obtaining a mutated allergen; identifying a hypoallergenic derivative of said wild-type allergen by detecting a destabilisation or change of the three-dimensional structure of the mutated allergen compared to the wild-type allergen by determining energy differences between the wild-type allergen and the mutant allergen expressed as a Z-score.

Abstract: The circuitry is used, for identifying television transmitters, in a television set receiving synchronizing signals and line flyback pulses characteristic of television transmitters, particularly for television receivers including a station finder circuit. The circuitry, during the time period of the line flyback pulses, derives samples of those signals appearing above the black level of the video signal, from the demodulated input signal. The number of amplitude jumps determined during the time period of the line flyback pulses is utilized as the criterion for identification of a television transmitter. The signals appearing above the black level of the video signal are inverted and then combined, in an AND circuit, with the line flyback pulses, and the output of the AND circuit is connected to a digital counter circuit to supply the output pulses thereto as counting pulses, with the flyback pulses being supplied to the digital counter circuit as gate pulses.