Abstract: A method and composition is provided for enhancing skin radiance and treating chronoaging conditions including wrinkles and dermatological disorders including acne, follicular and lesional papules, actinic keratoses, oily skin and rosacea comprising: (i) a safe and effective amount of an unsaturated C.sub.18 -C.sub.30 fatty acid ester of retinol; and (ii) a safe and effective amount of a cosmetically acceptable carrier, the composition being stable for at least four weeks at 43.degree. C. An unsaturated C.sub.18 -C.sub.30 fatty acid ester of retinol is the active component which is applied to the skin in a cosmetically acceptable carrier. The most preferred unsaturated retinol fatty acid ester is retinyl linoleate. The composition is stable and remains active for at least four weeks at 43.degree. C.

Abstract: A composition and method thereof treating or conditioning human skin, hair or nails is described. The composition is topically applied in an effective amount and contains from about 0.0001 to about 50 wt. % of a ceramide derivative containing sphingoid bases having amide, but not ester linkages to a 2 (alpha)-hydroxy carboxylic acid and a safe and effective amount of a pharmaceutical or cosmetically acceptable carrier. The composition effectively treats or conditions areas of fine flakes having histogram values of 10 to 128. Treated areas exhibit a desquamation value difference of 1.0 or greater at day 28 after treatment commences compared to a desquamation value of untreated areas.