Abstract: Technologies are provided for alignment of spatial transcriptome slides of biological tissue. The alignment of images and the coordinates of spots within transcriptome profiles of the biological tissue can utilize an alignment model that can be machine-learned and can receive both a displaced image to be aligned and a reference image as inputs. The alignment model may learn a diffeomorphic transformation between those images. Such a transformation can be readily applied to the alignment of the displaced image and to the alignment of the displaced coordinates of spots within the transcriptome profiles of transcriptome. In some cases, transcriptome data can be analyzed and cast in an image-like format, and can then be utilized as supplementary input to the alignment model. The alignment model can be trained in a tissue agnostic manner, such as by using synthetic images.

Abstract: A camera head of a dental camera for detecting caries in an interdental space has an illuminating device for illuminating a tooth adjacent to the interdental space, which includes an infrared light source. The camera head further includes optics which have an image plane and an object plane, wherein an image sensor is located in the image plane, and the object plane divides the space into two half spaces, wherein a first half space contains the optics and is located in front of the object plane, and a second half space is located behind the object plane, both as seen from the optics. The illuminating device and the optics are designed and arranged with respect to one another in such a way that the illuminating device is arranged in the first half space and infrared light exiting the illuminating device is aimed in the direction of the second half space.

Abstract: A discharge method discharges an at least partially flexible container without contamination. The container (1) is discharged into a base body (10). A liner (20) encloses a filling opening (11) of the base body (10) and is secured to the base body (10). A filling end (21) of the liner (20) is folded inwards such that a receiving region forms for the container (1). The receiving region is sealed such that a discharge opening formed by a knife (15) allows the container (1) to be discharged while being completely sealed off to the exterior.

Abstract: A lock system includes a first lock and a second lock each with two profile strips operable for engagement with an at least partially flexible bundle and effective to enable a connection of a first bundle with a second bundle in a closed docking position and for guidance of a flow in a flow direction through lock members from the first bundle into the second bundle in an open docking position. The second bundle provides the lock members facing toward the first bundle, which lock members in the open docking position engage the lock members of the first bundle and jointly with the lock members of the first bundle form a flow channel for flow in the flow direction. Additionally, a slider for connecting and separating such locks is provided.

Abstract: A dental camera system for creating an image of an object has a dental camera, which comprises a housing and optics arranged therein together with an image sensor. The dental camera system further comprises an evaluation unit which cooperates with the image sensor to capture the object. To achieve a dental camera system whereof the dental camera performs using optics without movable or controllable optical elements, it is provided for the optics to be plenoptic optics which are designed to determine a 4D light field when capturing the object and for the evaluation unit to be designed to calculate at least one representation of the captured object from the 4D light field.

Abstract: A system and method for connecting two flexible containers is provided, in particular for the environmentally sealed connecting of two open ends of tubular films. The method has at least the following method steps of: everting a first open end of a first flexible container over a first ring; everting a second open end of a second flexible container over a second ring, subsequently inserting the first ring through the second ring into the inside of the second flexible container; subsequently aligning, in a parallel and coaxial relationship, the rings in relation to one another; and abutting the rings with the ends clamped in between them.

Abstract: The invention relates to a discharge method for discharging an at least partially flexible container without contamination, in which method the container (1) is discharged into a base body (10), a liner (20) that encloses a filling opening (11) of the base body (10) being secured to the base body (10). According to the invention, a filling end (21) of the liner (20) is folded inwards such that a receiving region forms for the container (1). The receiving region is sealed in such a manner that a discharge opening formed by means of a knife (15) allows the container (1) to be discharged whilst being completely sealed off to the exterior.

Abstract: A camera head of a dental camera for detecting caries in an interdental space has an illuminating device for illuminating a tooth adjacent to the interdental space, which includes an infrared light source. The camera head further includes optics which have an image plane and an object plane, wherein an image sensor is located in the image plane, and the object plane divides the space into two half spaces, wherein a first half space contains the optics and is located in front of the object plane, and a second half space is located behind the object plane, both as seen from the optics. The illuminating device and the optics are designed and arranged with respect to one another in such a way that the illuminating device is arranged in the first half space and infrared light exiting the illuminating device is aimed in the direction of the second half space.

Abstract: A dental camera system for creating an image of an object has a dental camera, which comprises a housing and optics arranged therein together with an image sensor. The dental camera system further comprises an evaluation unit which cooperates with the image sensor to capture the object. To achieve a dental camera system whereof the dental camera performs using optics without movable or controllable optical elements, it is provided for the optics to be plenoptic optics which are designed to determine a 4D light field when capturing the object and for the evaluation unit to be designed to calculate at least one representation of the captured object from the 4D light field.

Abstract: A system and method for connecting two flexible containers is provided, in particular for the environmentally sealed connecting of two open ends of tubular films. The method has at least the following method steps of: everting a first open end of a first flexible container over a first ring; everting a second open end of a second flexible container over a second ring, subsequently inserting the first ring through the second ring into the inside of the second flexible container; subsequently aligning, in a parallel and coaxial relationship, the rings in relation to one another; and abutting the rings with the ends clamped in between them.

Abstract: The invention relates to a coupling closure for a docking device used for decanting, filling, and/or emptying containers, particularly in an environmentally isolated manner. The coupling closure has a closure side and a container side and comprises a nozzle stub and a cap which is mounted in the nozzle stub so as to be pivotable about an axis and has an external side that faces the closure side in the closed position. The invention further relates to a docking device for decanting, filling, and/or emptying containers, particularly in an environmentally isolated manner. The docking device comprises first and second disclosed coupling closures which can be placed flush against each other by the respective closure sides thereof. The invention also relates to a working platform, a locking unit for a docking device, and a method for decanting, filling, and/or emptying containers, particularly in an environmentally isolated manner.

Abstract: A docking device for transferring the contents of, filling, and/or emptying containers comprises first and second coupling latches positioned flush to one another along respective closing sides thereof. A locking unit is configured for locking together pipe nozzles of the first and second coupling latches. The locking unit includes at least one movable first arresting element that is present in a passage that has an opening to an exterior of the second coupling latch, and is configured to interact with a corresponding second arresting element present on an exterior of the pipe nozzle of the second coupling latch. The docking device further comprises a bolt that is movable in a cylinder. The bolt has a first section with a first diameter, a second section with a second diameter that is smaller than the first diameter, and a third transfer section between the first and second section with a tapering diameter.

Abstract: Coupling locks, attachment modules, and docking devices allow for re-filling, filling and/or emptying of containers in a manner that is insulated against the environment. An attachment module includes a coupling lock and a locking clamp, where the coupling lock includes a pipe nozzle and a closing flap. A first clamping element is located on an outer side of the pipe nozzle to engage with a second clamping element by means of the locking clamp to create a temporary connection. A docking device includes the first coupling lock or the attachment module, and a second coupling lock, complementary to the first coupling lock. When the closing flaps of the first and second coupling locks are brought into contact with each other, they can be pivoted from a closed position, where they lock the transfer channel formed by the pipe nozzles, around a shared axis into an open position.

Abstract: A handpiece camera, comprising an illumination device optical elements, and an image converter. A housing is provided with an entrance window, through which an observation light returning from an examination area shines in, which is subsequently conducted to the image converter by the optical elements. The camera has a head part and a handle part, which are detachably connected to one another. The handle part can be adjusted to a wide variety of purposes when combined with different head parts.

Abstract: The proposed invention provides a lock system involves a first lock and a second lock each with two profile strips operable for engagement with an at least partially flexible bundle and effective to enable an environmentally-sealed connection of a first bundle with a second bundle in a closed docking position and for an environmentally-sealed guidance of a flow in a flow direction (D) through the lock members from the first bundle into the second bundle in an open docking position. The second bundle provides similar lock members facing toward the first bundle, which lock members in the opened docking position engage the lock members of the first bundle and jointly with the lock members of the first bundle forms a flow channel for flow in the flow direction. Additionally the invention relates to a slider for connecting and separating such locks.

Abstract: The present invention relates to a method of disaster recovery in data processing systems and to a recovery system. The invention allows for easy, fast and reliable recovery of a data processing system in a disaster situation. Unmodified backup data is stored to a target data processing system, the hardware of the target data processing system being different from the hardware of the source data processing system, from which the backup data originated. The stored backup data is then adapted to the hardware of the target data processing system by a remote recovery system using previously obtained reference data.

Abstract: The invention relates to a docking device for transferring the contents of, filling, and/or emptying containers, comprising first and second coupling closures flushly applicable or positioned flush to one another via the respective closing sides thereof. The docking device is equipped with at least one locking unit suitable for locking the pipe socket of the first and second coupling closure, said locking unit comprising at least one movable first locking means present in a passage having an opening to the exterior of the second coupling closure, particularly in the form of a ball, and being suitable to cooperate with a corresponding second locking means present on the exterior of the pipe socket of the second coupling closure. The docking device further comprises a pin movable in a cylinder, said pin comprising a first section having a first diameter and a second section having a second diameter that is less than the diameter of the first section.

Abstract: The present invention relates to a coupling seal for a container flexible at least in sections, for example a bag or a hose, comprising a first and a second longitudinal sealing bead, which in each case are fitted with first and second sealing elements, and a coupler seal, which is provided with a longitudinal bead with adjacent third and fourth sealing elements, which can be connected reversibly, in particular sealed to the environment, with the first or respectively second sealing elements of the first and second sealing beads. Furthermore, the invention relates to a docking device, formed by two inventive coupling seals. At this point, the first and second sealing elements of the first coupling seal engage in each case in complementary first and second sealing elements of the second coupling seal. In addition, the invention relates to a container flexible at least in sections, whereof the opening is fitted with an inventive coupling seal.

Abstract: An attachment (40, 40a, 40b) for a diagnostic (10) comprises a coupling section (42) configured for the detachable connection to a head region (14) of a diagnostic camera (10), and a dimensionally stable spacer (44) that is connected to said section and has a free end section (46).

Abstract: The invention relates to a coupling closure for a docking device used for decanting, filling, and/or emptying containers, particularly in an environmentally isolated manner. Said coupling closure has a closure side and a container side and comprises a nozzle stub and a cap which is mounted in said nozzle stub so as to be pivotable about an axis and has an external side that faces the closure side in the closed position. The invention further relates to a docking device for decanting, filling, and/or emptying containers, particularly in an environmentally isolated manner. Said docking device comprises first and second disclosed coupling closures which can be placed flush against each other by means of the respective closure sides thereof. The invention also relates to a working platform, a locking unit for a docking device, and a method for decanting, filling, and/or emptying containers, particularly in an environmentally isolated manner.