Patents by Inventor Peter Leedman

Peter Leedman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MicroRNAs and Uses Thereof
    Publication number: 20150126581
    Abstract: Provided herein are methods for inhibiting expression of DOHH in a cell, and for inhibiting hypusination of eIF5A in a cell, the methods comprising contacting a cell with a miRNA or a nucleic acid molecule encoding the miRNA, wherein the miRNA binds to the 3?UTR of the DOHH mRNA and wherein binding results in a reduction in DOHH expression. Also provided are methods for reducing cellular proliferation and for treating diseases associated with abnormal cellular proliferation.
    Type: Application
    Filed: March 8, 2013
    Publication date: May 7, 2015
    Applicant: The University of Western Australia
    Inventors: Peter Leedman, Keith Giles, Michael Epis, Andrew Barker
  • Method of modulation of expression of epidermal growth factor receptor(EGFR) involving miRNA
    Patent number: 8673872
    Abstract: The present invention relates to a method for modulating the expression of epidermal growth factor receptor (EGFR) and its downstream signalling effectors. In particular, the present invention relates to a method for modulating the expression of epidermal growth factor receptor (EGFR) or like molecule in a cell comprising contacting said cell with an agent capable of directly or indirectly interacting with the 3?-untranslated region (UTR) of the mRNA of said EGFR or like molecule, wherein the UTR is encoded by a sequence which comprises a sequence having at least about 70% identity with at least one sequence selected from the group consisting of the sequences set forth in SEQ ID NOs: 1-36.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: March 18, 2014
    Assignee: The University of Western Australia
    Inventors: Peter Leedman, Keith Giles, Rebecca Jane Webster
  • Method of modulation of expression of epidermal growth factor receptor(egfr) involving mirna
    Publication number: 20100016411
    Abstract: The present invention relates to a method for modulating the expression of epidermal growth factor receptor (EGFR) and its downstream signalling effectors. In particular, the present invention relates to a method for modulating the expression of epidermal growth factor receptor (EGFR) or like molecule in a cell comprising contacting said cell with an agent capable of directly or indirectly interacting with the 3?-untranslated region (UTR) of the mRNA of said EGFR or like molecule, wherein the UTR is encoded by a sequence which comprises a sequence having at least about 70% identity with at least one sequence selected from the group consisting of the sequences set forth in SEQ ID NOs: 1-36.
    Type: Application
    Filed: August 28, 2007
    Publication date: January 21, 2010
    Inventors: Peter Leedman, Keith Gilles, Rebecca Jane Webster
  • SRA binding protein
    Publication number: 20090312245
    Abstract: An isolated polypeptide comprising: (i) SEQ ID No: 2; (ii) amino acids 27 to 109 of SEQ ID No: 2 (iii) amino acids 22 to 109 of SEQ ID No: 2 (iv) amino acids 21-91 of SEQ ID No: 2 (v) amino acids 21-26 and/or 60-67 of SEQ ID No: 2 or (vi) a functional variant of any one of (i) to (v).
    Type: Application
    Filed: January 22, 2008
    Publication date: December 17, 2009
    Applicant: The University of Western Australia
    Inventors: Peter Leedman, Esme Hatchell, Shane Colley