Patents by Inventor Peter Lowe

Peter Lowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11673931
    Abstract: The present invention relates to new immunocytokines which are useful for the treatment of cancer. These fusion proteins comprise (i) an antibody or antigen-binding fragment thereof fused to (ii) a cleavable peptide linker, and (iii) cytokine, or functional fragments thereof. Methods of treatment using these immunocytokines are also disclosed.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: June 13, 2023
    Assignee: PIERRE FABRE MEDICAMENT
    Inventors: Peter Lowe, Jean-François Haeuw, Alicia Contet, Céline Bertaux, Barbara Akla, Marie-Claire Janin-Bussat, Martine Malissard, Juliette Trepreau
  • Publication number: 20230174603
    Abstract: The present invention relates to new immunocytokines which are useful for the treatment of cancer. These fusion proteins comprise (i) an antibody or antigen-binding fragment thereof fused to (ii) a cleavable peptide linker, and (iii) cytokine, or functional fragments thereof. Methods of treatment using these immunocytokines are also disclosed.
    Type: Application
    Filed: April 1, 2021
    Publication date: June 8, 2023
    Applicant: PIERRE FABRE MEDICAMENT
    Inventors: Peter LOWE, Martine MALISSARD, Barbara AKLA, Juliette TREPREAU
  • Publication number: 20220048966
    Abstract: The present invention relates to new immunocytokines which are useful for the treatment of cancer. These fusion proteins comprise (i) an antibody or antigen-binding fragment thereof fused to (ii) a cleavable peptide linker, and (iii) cytokine, or functional fragments thereof. Methods of treatment using these immunocytokines are also disclosed.
    Type: Application
    Filed: September 30, 2019
    Publication date: February 17, 2022
    Applicant: PIERRE FABRE MEDICAMENT
    Inventors: Peter LOWE, Jean-François HAEUW, Alicia CONTET, Céline BERTAUX, Barbara AKLA, Marie-Claire JANIN-BUSSAT
  • Publication number: 20200308242
    Abstract: The present invention relates to new immunocytokines which are useful for the treatment of cancer. These fusion proteins comprise (i) an antibody or antigen-binding fragment thereof fused to (ii) a cleavable peptide linker, and (iii) cytokine, or functional fragments thereof. Methods of treatment using these immunocytokines are also disclosed.
    Type: Application
    Filed: April 1, 2020
    Publication date: October 1, 2020
    Applicant: PIERRE FABRE MEDICAMENT
    Inventors: Peter LOWE, Jean-François HAEUW, Alicia CONTET, Céline BERTAUX, Barbara AKLA, Marie-Claire JANIN-BUSSAT
  • Publication number: 20190071518
    Abstract: The present disclosure relates to the treatment of cancers and, more particularly, to the treatment of ADAM17 substrate dependant cancers which are refractory. The pharmaceutical composition contains an ADAM17 antibody (it recognizes an epitope within the membrane proximal domain of ADAM17 localized between the residues 564 and 642) characterized by the sequences of its variable chains.
    Type: Application
    Filed: January 4, 2016
    Publication date: March 7, 2019
    Inventors: Peter LOWE, Nicolas BOUTE, Alexandra JOUHANNEAUD
  • Publication number: 20180057601
    Abstract: The present disclosure relates to a novel humanized antibody capable of binding to ADAM17 and also the amino and nucleic acid sequences coding for said antibody. From one aspect, the disclosure relates to a novel humanized antibody, or antigen-binding fragments, capable of binding to ADAM17 with anti-tumour activities. The disclosure also comprises the use of said humanized antibody as a drug for the treatment of cancer. Finally, the invention comprises compositions comprising said humanized antibody, alone or in combination or conjugation with other anticancer compounds, and the use of same for the treatment of cancer.
    Type: Application
    Filed: January 4, 2016
    Publication date: March 1, 2018
    Inventors: Peter LOWE, Sven BERGER, Michael TESAR
  • Patent number: 9862759
    Abstract: The invention relates to a method for generating a DNA sequence coding for the heavy chain or the light chain of at least one antibody from RNA from a cell capable of producing an antibody. More particularly, the invention relates to the generation of a monoclonal antibody library. The invention also relates to the use of an antibody library for screening monoclonal antibodies, preferably human antibodies for treating cancer.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: January 9, 2018
    Assignee: PIERRE FABRE MEDICAMENT
    Inventors: Peter Lowe, Cédric Bes, Nicolas Boute
  • Publication number: 20160326257
    Abstract: The present invention relates to a novel antibody capable of binding to ADAM17 and also the amino and nucleic acid sequences coding for said antibody. From one aspect, the invention relates to a novel antibody, or antigen-binding fragments, capable of binding to ADAM17 with anti-tumour activities. The invention also comprises the use of said antibody as a drug for the treatment of cancer. Finally, the invention comprises compositions comprising said antibody, alone or in combination or conjugation with other anti-cancer compounds, and the use of same for the treatment of cancer.
    Type: Application
    Filed: December 24, 2014
    Publication date: November 10, 2016
    Applicant: PIERRE FABRE MEDICAMENT
    Inventor: Peter LOWE
  • Patent number: 9182748
    Abstract: Systems are described herein for providing card reader configuration and access control, including a card reader, a remote computing device, and a communications network coupled to the card reader and the remote computing device. The card reader is configured to connect to the remote computing device via the communications network, transmit a request to the remote computing device via the communications network, receive data from the remote computing device via the communications network, and configure operational settings based on the received data. The remote computing device is configured to receive the request from the card reader via the communications network, generate data responsive to the request, and transmit the data to the card reader via the communications network.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: November 10, 2015
    Assignee: Identive Group, Inc.
    Inventors: Matthew Herscovitch, Jason Hart, Peter Lowe
  • Patent number: 9141091
    Abstract: Methods and systems are described herein for providing configuration and access control of a card reader using a secure channel between the card reader and a remote computing device. The card reader transmits a request for service to the remote computing device via a cloud-based communications network. The remote computing device receives the request for service via the cloud-based communications network and generates service instructions based on the received request for service. The remote computing device transmits the service instructions to the card reader via the cloud-based communications network. The card reader receives the service instructions from the remote computing device via the cloud-based communications network and configures operational settings based on the received service instructions.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: September 22, 2015
    Assignee: Identive Group, Inc.
    Inventors: Matthew Herscovitch, Jason Hart, Peter Lowe
  • Patent number: 8728983
    Abstract: The invention relates to a minimized phage display vector comprising at least a cloning cassette, a phage display cassette and a bacterial cassette, said cloning cassette comprising a nucleic acid sequence encoding a polypeptide corresponding at least to the intra-domain loop of a constant domain of an antibody. It also relates to their uses for the production of libraries of phages, each phage expressing on its surface a binding protein to be screened for its capacity to bind a binding partner.
    Type: Grant
    Filed: November 18, 2010
    Date of Patent: May 20, 2014
    Assignee: Pierre Fabre Medicament
    Inventors: Peter Lowe, Sven Berger
  • Publication number: 20120322678
    Abstract: The invention relates to a minimized phage display vector comprising at least a cloning cassette, a phage display cassette and a bacterial cassette, said cloning cassette comprising a nucleic acid sequence encoding a polypeptide corresponding at least to the intra-domain loop of a constant domain of an antibody. It also relates to their uses for the production of libraries of phages, each phage expressing on its surface a binding protein to be screened for its capacity to bind a binding partner.
    Type: Application
    Filed: November 18, 2010
    Publication date: December 20, 2012
    Applicant: PIERRE FABRE MEDICAMENT
    Inventors: Peter Lowe, Sven Berger
  • Publication number: 20120286772
    Abstract: This invention relates to the pipeline corrosion prevention and third party strike pipeline damage. The detector comprises of dual axis Anisotropic Magnetoresistive (AMR) magnetic sensor, analog signal conditional circuitry, digital circuitry, and a display. A pipe current magnitude and direction is measured via magnetic field surrounding the pipe. Magnetic field is sensed by the Anisotropic Magnetoresistive (AMR) magnetic sensor. The sensor converts magnetic field values into an electrical potential difference. This potential difference is converted into digital data and displayed on either computer screen or an LCD display. The current reader will be installed on a pipe and take continuous magnetic field reads (amplitude and direction). Third party strike damage is detected by monitoring magnetic fields around a pipe and comparing them to a baseline magnetic field. Any mechanical damage on a pipe will distort baseline magnetic field value around the pipeline.
    Type: Application
    Filed: May 9, 2011
    Publication date: November 15, 2012
    Inventors: Mark John Byerley, SR., Roman Rafailovich Chak, Peter Lowe Harkins
  • Publication number: 20110209415
    Abstract: A security screening facility for a location in which passengers travel from a check-in location within an in-secure area of a terminal to a secure part of the terminal for eventually boarding a transport vehicle. The facility includes a prefabricated building located alongside the terminal which houses body scanning apparatus.
    Type: Application
    Filed: May 25, 2010
    Publication date: September 1, 2011
    Inventors: Peter Lowes, Beverley Bowles
  • Publication number: 20110003705
    Abstract: The invention relates to a method for generating a DNA sequence coding for the heavy chain or the light chain of at least one antibody from RNA from a cell capable of producing an antibody. More particularly, the invention relates to the generation of a monoclonal antibody library. The invention also relates to the use of an antibody library for screening monoclonal antibodies, preferably human antibodies for treating cancer.
    Type: Application
    Filed: December 4, 2008
    Publication date: January 6, 2011
    Applicant: PIERRE FABRE MEDICAMENT
    Inventors: Peter Lowe, Cédric Bes, Nicolas Boute
  • Patent number: 7575112
    Abstract: A system for screening items of baggage comprises attaching to each baggage item at a check-in location within a terminal an electronic tag which is periodically scanned as the item travels via baggage sortation system from the check-in location and a loading location. All baggage items are diverted from the sortation system to an explosive detection screening system housed within a prefabricated building alongside the terminal. Baggage items which are not cleared by the explosive detection screening system are retained within the building for further inspection and cleared baggage items are re-introduced into the sortation system for travel to the loading location.
    Type: Grant
    Filed: September 10, 2004
    Date of Patent: August 18, 2009
    Inventors: Peter Lowes, Beverley Bowles
  • Publication number: 20070230656
    Abstract: A system for screening items of baggage comprises attaching to each baggage item at a check-in location within a terminal an electronic tag which is periodically scanned as the item travels via baggage sortation system from the check-in location and a loading location. All baggage items are diverted from the sortation system to an explosive detection screening system housed within a prefabricated building alongside the terminal. Baggage items which are not cleared by the explosive detection screening system are retained within the building for further inspection and cleared baggage items are re-introduced into the sortation system for travel to the loading location.
    Type: Application
    Filed: September 10, 2004
    Publication date: October 4, 2007
    Inventors: Peter Lowes, Beverley Bowles
  • Publication number: 20070229273
    Abstract: An RFID transponder detector is provided having a coupled oscillator system. Coupled first and second LC pairs of the system produce a detection signal each time a combination of pulses is applied to the LC pairs. Application of the pulses is repeated periodically to produce a sequence fo detection signals having two different first and second detection frequencies. Transmitting the sequence of detection signals results in corresponding first and second response signals having the first and second detection frequencies at the LC pairs. Values of a preselected detection parameter for the detection signals are compared to the values of the detection parameter for the response signals to determine if a transponder having a transponder resonant frequency corresponding to the first or second detection frequency is present in a proximal space of the transponder detector.
    Type: Application
    Filed: March 31, 2006
    Publication date: October 4, 2007
    Inventors: James Hoemann, Peter Lowe
  • Publication number: 20070136075
    Abstract: An air travel system in which pre-flight check-in of passengers and luggage items are conducted at passenger confirmed addresses remote from the airport of departure. All relevant luggage items are collected during the course of the pre-flight check-in and transported in secure vehicles to the airport of departure for security checks to be made. Each passenger for whom luggage items are collected receives a preliminary boarding pass including inter alia flight details, the preliminary boarding pass being exchanged with a confirmed boarding pass airside of the airport of departure.
    Type: Application
    Filed: August 20, 2004
    Publication date: June 14, 2007
    Inventors: Peter Lowes, Beverley Bowles
  • Patent number: D814091
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: March 27, 2018
    Inventor: Peter Lowe