Abstract: A graph database system stores and analyzes connections and relationships between entities using a database structure that represents users, messages, threads, and attachments as nodes with interconnecting edges. The system implements a hybrid approach to electronic communication classification combining self-hosted language models with computer server clustering for pattern matching and suggestion generation. Additionally, the system includes mechanisms for creating and suggesting reusable electronic communication components based on semantic analysis of communication patterns. The system architecture enables relationship analysis, digital content management, and privacy-preserving electronic communication classification.

Abstract: The present disclosure provides systems and methods for synchronizing email accounts across different email clients. Permission is obtained from a user to access a first email account and a second email account, where the first and second email accounts are accessible via different email clients. Existing emails are uploaded from the second email account to the first email account and indications of changes in resources associated with the email accounts are received and replicated across accounts to maintain synchronization. Additionally, API usage is managed by determining an API quota count and pending API usage count and queueing the replication of changes between email accounts until API quota limits will not be exceeded. Furthermore, search queries received when the accounts are not synchronized are translated into a format compatible with an API of the second email client. The second email client is queried and a response to the translated search query is received and displayed.

Abstract: A graph database system stores and analyzes connections and relationships between entities using a database structure that represents users, messages, threads, and attachments as nodes with interconnecting edges. The system implements a hybrid approach to electronic communication classification combining self-hosted language models with computer server clustering for pattern matching and suggestion generation. Additionally, the system includes mechanisms for creating and suggesting reusable electronic communication components based on semantic analysis of communication patterns. The system architecture enables relationship analysis, digital content management, and privacy-preserving electronic communication classification.

Abstract: The present disclosure provides systems and methods for generating reusable mail blocks based on recurring patterns of text in groups of stored emails and suggesting relevant mail blocks to a user during email composition. Emails are stored in a database and similarity scores between emails are calculated based on semantic similarities. Emails with a similarity score satisfying a predetermined threshold are grouped together. Recurring text patterns within grouped emails are recognized to generate mail blocks containing generalized text. Text input by a user in an email composer is monitored for similarities with existing mail blocks. When a similarity is detected, insertion of a relevant mail block is suggested to the user.

Abstract: The present disclosure provides systems and methods for testing the scalability of a commit of an application and the measurement of performance metrics indicating the commit has satisfied a performance threshold. A plurality of mock users of a first commit of an application included in a first stack are simulated and a mocked import queue for the first commit that simulates simultaneous performance of a plurality of actions associated with the application is initiated. Normal network traffic performed by the plurality of mock users is simulated as occurring simultaneously to the plurality of actions simulated using the mocked import queue. A performance metric of the application is measured and, in some embodiments, associated with the first commit.

Abstract: An electronic device receives a first input on a mailbox user interface to select an interface element indicating a particular layout among multiple layouts. These layouts represent different ways of arranging email messages and are each associated with an identifier. Each layout defines a set of columns, with each column representing values derived from email message properties. The layouts are stored on a backend server system. In response to the first input, the device retrieves the particular layout from the backend server system based on its identifier. The mailbox user interface then displays multiple email messages arranged in the selected layout, including a table with multiple rows and a specific set of columns defined by the layout. Each row corresponds to an email message, with values for the columns derived from the properties of the email messages.

Abstract: The system obtains multiple views associated with multiple messages. A view among the multiple views includes a visual appearance and a criterion among the multiple criteria defining a message to include in the view. The system obtains the multiple messages and analyzes the multiple messages using the multiple criteria to determine a number of messages satisfying the criterion. The system determines whether the number of messages satisfying the criterion among the multiple criteria satisfies a predetermined threshold. Upon determining that the number of messages satisfying the criterion among the multiple criteria satisfies the predetermined threshold, the system suggests organizing the number of messages satisfying the criterion according to the view. The system receives an approval to organize the number of messages satisfying the criterion according to the view and presents the number of messages according to the visual appearance associated with the view.

Abstract: The system obtains messages including multiple properties, such as a sender, a receiver, and content. The system creates a database to store the messages and presents the database in a user interface including a table including rows and columns. The database can be customized by including a custom column among the multiple columns. The system customizes the user interface by creating custom views of the database. The system receives an indication to create a view of the multiple messages, where the indication to create the view includes a criterion to select a subset of messages from the messages. The system creates the view including multiple layouts configured to visually provide important information associated with the subset of messages.

Abstract: The system obtains multiple views associated with a first multiplicity of messages, where a view among the multiple views includes a criterion, a visual appearance, and an action. The criterion defines a message to include in the view, and the action is configured to trigger automatically when the message is included in the view. The system applies the view to the second multiplicity of messages by: selecting a subset of messages among the second multiplicity of messages according to the criterion; presenting the subset of messages to the user according to the visual appearance associated with the view; and performing the action on the subset of messages.

Abstract: The system provides a table including multiple email messages in a user interface. The table includes multiple rows and multiple columns, where the multiple columns correspond to respective properties of the email messages and a row corresponds to one or more email messages. The system modifies the user interface by receiving an indication to modify the table with content of a particular type. The indication includes a selection of one or more rows of the multiple rows in the table wherein the selection of the one or more rows is across at least part of the multiple columns of the table. The system causes a generative artificial intelligence (AI) system to create content of the particular type and the selection of the one or more rows. The system modifies the user interface by adding the content of the particular type created by the generative AI system to the user interface.

Abstract: The system obtains multiple email messages and provides a user interface to display the multiple email messages. The multiple email messages can be configured to be presented in a table including multiple rows and multiple columns. The user interface can include a unique identification (ID) associated with the row, and a unique ID associated with the column. The system can customize the user interface by receiving an indication to create a graphical representation of the content of the multiple email messages. The indication can include obtaining a formula indicating an operation to be performed on a content identified by the row and/or the column. The system can create the graphical representation of the operation applied to the content identified by the row and/or the column and provide the graphical representation on the user interface.

Abstract: Methods for producing a protein extract from cells, such as cells containing viral proteins, are provided. In general terms, the methods involve: increasing the pH of the cells to a pH of at least about pH 10.0 to produce an intermediate composition, and then, in the presence of a non-ionic detergent, neutralizing the pH of the intermediate composition to produce the protein extract. Kits and compositions for practicing the subject methods are also provided.

Abstract: Methods for producing a protein extract from cells, such as cells containing viral proteins, are provided. In general terms, the methods involve: increasing the pH of the cells to a pH of at least about pH 10.0 to produce an intermediate composition, and then, in the presence of a non-ionic detergent, neutralizing the pH of the intermediate composition to produce the protein extract. Kits and compositions for practicing the subject methods are also provided.

Abstract: The subject invention provides an antibody composition for detecting E6 protein of at least one HPV strain in a sample. The subject antibodies may be used to detect oncogenic HPV E6 proteins in a sample, and the antibodies find use in a variety of diagnostic and therapeutic applications, including methods of diagnosing and treating cancer. Kits for performing the subject methods and containing the subject antibodies are also provided. Also disclosed in the present invention is a method of generating an antibody that specifically binds to amino-terminus of E6 proteins of at least two HPV strains.

Abstract: Methods for producing a protein extract from cells, such as cells containing viral proteins, are provided. In general terms, the methods involve: increasing the pH of the cells to a pH of at least about pH 10.0 to produce an intermediate composition, and then, in the presence of a non-ionic detergent, neutralizing the pH of the intermediate composition to produce the protein extract. Kits and compositions for practicing the subject methods are also provided.

Abstract: The subject invention provides antibodies, including polyclonal and monoclonal antibodies, that bind to E6 proteins from at least three oncogenic strains of HPV. In general, the antibodies bind to amino acids motifs that are conserved between the E6 proteins of different HPV strains, particularly HPV strains 16 and 18. The subject antibodies may be used to detect HPV E6 protein in a sample, and, accordingly, the antibodies find use in a variety of diagnostic applications, including methods of diagnosing cancer. Kits for performing the subject methods and containing the subject antibodies are also provided.

Abstract: The subject invention provides an antibody composition for detecting E6 protein of at least one HPV strain in a sample. The subject antibodies may be used to detect oncogenic HPV E6 proteins in a sample, and the antibodies find use in a variety of diagnostic and therapeutic applications, including methods of diagnosing and treating cancer. Kits for performing the subject methods and containing the subject antibodies are also provided. Also disclosed in the present invention is a method of generating an antibody that specifically binds to amino-terminus of E6 proteins of at least two HPV strains.

Abstract: The subject invention provides antibodies, including polyclonal and monoclonal antibodies, that bind to E6 proteins from at least three oncogenic strains of HPV. In general, the antibodies bind to amino acids motifs that are conserved between the E6 proteins of different HPV strains, particularly HPV strains 16 and 18. The subject antibodies may be used to detect HPV E6 protein in a sample, and, accordingly, the antibodies find use in a variety of diagnostic applications, including methods of diagnosing cancer. Kits for performing the subject methods and containing the subject antibodies are also provided.

Abstract: The present application describes methods for detecting influenza A and/or influenza B and/or distinguishing between pathogenic and seasonal influenza A subtypes. Many of these preferred formats employ pan-specific antibodies (i.e., that react with all or at least multiple strains within an influenza type) to detect presence of influenza A and/or influenza B and PDZ domains in combination with panspecific antibodies to influenza A to distinguish pathogenic and seasonal influenza A subtypes.

Abstract: The subject invention provides antibodies, including polyclonal and monoclonal antibodies, that bind to E6 proteins from at least three oncogenic strains of HPV. In general, the antibodies bind to amino acids motifs that are conserved between the E6 proteins of different HPV strains, particularly HPV strains 16 and 18. The subject antibodies may be used to detect HPV E6 protein in a sample, and, accordingly, the antibodies find use in a variety of diagnostic applications, including methods of diagnosing cancer. Kits for performing the subject methods and containing the subject antibodies are also provided.