Patents by Inventor Peter M. Smid

Peter M. Smid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 14.alpha.,17.alpha.-dihydroxy-17.beta.-substituted steroids
    Patent number: 5093502
    Abstract: A process for the preparation of novel 14.alpha., 17.alpha.-dihydroxy-17.beta.-substituted steroids by reacting 14.alpha.-hydroxy-17-oxo-steroids with metal organic compounds and the use of the said novel steroids in the production of 14.alpha., 17.alpha.-methylenedioxy-pregnane derivatives.
    Type: Grant
    Filed: February 16, 1990
    Date of Patent: March 3, 1992
    Assignee: Akzo N.V.
    Inventors: Peter M. Smid, Willem J. Van Zoest, Pieter G. Weber, Arthur F. Marx
  • New process for the preparation 17.beta.-hydroxy-3-oxo-17.alpha.-pregnene and pregnadiene-21-carboxylic acid .gamma.-lactones
    Patent number: 4267106
    Abstract: A process is disclosed for the preparation of 17.beta.-hydroxy-3-oxo-l7.alpha.-pregn-4-ene-21-carboxylic acid .gamma.-lactone and 17.beta.-hydroxy-3-oxo-17.alpha.-pregna-4,6-diene-21-carboxylic acid .gamma.-lactone of the formula: ##STR1## wherein the dotted line between the 6-7 positions indicates an optional double bond, which is present in the latter compound, by reacting an androst-5-ene-17-one derivative with an organo-phosphorus compound. These lactones are valuable intermediates in the synthesis of spironolactone.
    Type: Grant
    Filed: August 15, 1979
    Date of Patent: May 12, 1981
    Assignee: Gist Brocades N.V.
    Inventors: Arthur F. Marx, Peter M. Smid, Pieter Vellekoop