Abstract: A monitoring device for a high-voltage onboard electrical system of an electrically operable vehicle. The high-voltage onboard electrical system includes a high-voltage energy storage device that is couplable to an electrically positive and an electrically negative charge line. The electrically positive charge line is couplable to a positive electric voltage of a charging device via a charging connection to charge the high-voltage energy storage device and the electrically negative charge line is couplable to a negative electric voltage of the charging device to charge the high voltage energy storage device. The monitoring device has a control unit with a current sensor which is configured to determine the sum of the electric currents of the positive and the negative charge lines. The control unit is configured to separate the positive and the negative charge lines from the high-voltage onboard electrical system upon detecting a fault.

Abstract: A sorption heat pump having an evaporator containing a working fluid to evaporate the fluid to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a vapor pathway connecting the evaporator and sorber, and a thermal control unit controlling the rate of vapor flow between the evaporator and sorber through the pathway, and being selectively operable to permit, stop and restart the flow of gas through the pathway. The pump may be used with a compartment storing temperature sensitive material. The evaporator may be positioned inside and the sorber outside the compartment, or the sorber may be positioned inside and the evaporator outside the compartment. The pump may be used in an apparatus including both cool and warm compartments, with an insulation layer in each. A method is disclosed for reusing the pump after the sorption material has been sorbed.

Abstract: A temperature controller for a sorption system having an evaporator to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a flow channel extending between the evaporator and sorber to provide a gas pathway connecting them, a valve to control the rate of gas flow in the flow channel, and a temperature sensor positioned to measure the temperature of an evaporator surface or the air adjacent thereto indicative of an evaporator surface temperature, and generate a temperature signal. The controller includes an inflatable member having first and second inflation states, and a control unit configured to evaluate the temperature signal and in response control the state of inflation of the inflatable member and thereby the operation of the valve to control the rate of gas flow between the evaporator and sorber through the gas pathway.

Abstract: A temperature controller for a sorption system having an evaporator to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a flow channel extending between the evaporator and sorber to provide a gas pathway connecting them, a valve to control the rate of gas flow in the flow channel, and a temperature sensor positioned to measure the temperature of an evaporator surface or the air adjacent thereto indicative of an evaporator surface temperature, and generate a temperature signal. The controller includes an inflatable member having first and second inflation states, and a control unit configured to evaluate the temperature signal and in response control the state of inflation of the inflatable member and thereby the operation of the valve to control the rate of gas flow between the evaporator and sorber through the gas pathway.

Abstract: A sorption heat pump having an evaporator containing a working fluid to evaporate the fluid to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a vapor pathway connecting the evaporator and sorber, and a thermal control unit controlling the rate of vapor flow between the evaporator and sorber through the pathway, and being selectively operable to permit, stop and restart the flow of gas through the pathway. The pump may be used with a compartment storing temperature sensitive material. The evaporator may be positioned inside and the sorber outside the compartment, or the sorber may be positioned inside and the evaporator outside the compartment. The pump may be used in an apparatus including both cool and warm compartments, with an insulation layer in each. A method is disclosed for reusing the pump after the sorption material has been sorbed.

Abstract: A thermally insulated transport container for use with an ice battery, having an internal usable volume for freeze-free cooling of temperature-sensitive products placed therein, the usable volume having an outward usable volume portion, an internal cold storage volume sized to receive the ice battery, the cold storage volume having an inward cold storage volume portion adjacent to the outward usable volume portion to define a common interface of the usable volume and the cold storage volume, a heat-conducting liner extending about the usable volume and having a heat-conducting liner portion located between the outward usable volume portion and the inward cold storage volume portion, and a phase change material (PCM) container positioned adjacent to the heat-conducting liner portion at the common interface and in heat-conducting contact with the heat conduction liner portion, the PCM container sized to contain a phase change material.

Abstract: A temperature controller for a sorption system having an evaporator to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a flow channel extending between the evaporator and sorber to provide a gas pathway connecting them, a valve to control the rate of gas flow in the flow channel, and a temperature sensor positioned to measure the temperature of an evaporator surface or the air adjacent thereto indicative of an evaporator surface temperature, and generate a temperature signal. The controller includes an inflatable member having first and second inflation states, and a control unit configured to evaluate the temperature signal and in response control the state of inflation of the inflatable member and thereby the operation of the valve to control the rate of gas flow between the evaporator and sorber through the gas pathway.

Abstract: A sorption heat pump having an evaporator containing a working fluid to evaporate the fluid to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a vapor pathway connecting the evaporator and sorber, and a thermal control unit controlling the rate of vapor flow between the evaporator and sorber through the pathway, and being selectively operable to permit, stop and restart the flow of gas through the pathway. The pump may be used with a compartment storing temperature sensitive material. The evaporator may be positioned inside and the sorber outside the compartment, or the sorber may be positioned inside and the evaporator outside the compartment. The pump may be used in an apparatus including both cool and warm compartments, with an insulation layer in each. A method is disclosed for reusing the pump after the sorption material has been sorbed.

Abstract: A temperature controller for a sorption system having an evaporator to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a flow channel extending between the evaporator and sorber to provide a gas pathway connecting them, a valve to control the rate of gas flow in the flow channel, and a temperature sensor positioned to measure the temperature of an evaporator surface or the air adjacent thereto indicative of an evaporator surface temperature, and generate a temperature signal. The controller includes an inflatable member having first and second inflation states, and a control unit configured to evaluate the temperature signal and in response control the state of inflation of the inflatable member and thereby the operation of the valve to control the rate of gas flow between the evaporator and sorber through the gas pathway.

Abstract: A temperature controller for a sorption system having an evaporator to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a flow channel extending between the evaporator and sorber to provide a gas pathway connecting them, a valve to control the rate of gas flow in the flow channel, and a temperature sensor positioned to measure the temperature of an evaporator surface or the air adjacent thereto indicative of an evaporator surface temperature, and generate a temperature signal. The controller includes an inflatable member having first and second inflation states, and a control unit configured to evaluate the temperature signal and in response control the state of inflation of the inflatable member and thereby the operation of the valve to control the rate of gas flow between the evaporator and sorber through the gas pathway.

Abstract: Herein is reported a method for producing a fusion-polypeptide comprising the seeps of a) cultivating a mammalian cell comprising a nucleic acid encoding a variant fusion-polypeptide wherein the amino acid sequence of the fusion-polypeptide has been modified by replacing in a pro-fusion-polypeptide the endogenous protease cleavage site between the pro-peptide and the fusion-polypeptide with an exogenous (with respect to the origins of the parts of the fusion-polypeptide) or artificial protease cleavage site, and b) recovering the fusion-polypeptide or fusion-pro-polypeptide from the cell or the cultivation median and thereby producing the (recombinant) fusion-polypeptide.

Abstract: A sorption heat pump having an evaporator containing a working fluid to evaporate the fluid to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a vapor pathway connecting the evaporator and sorber, and a thermal control unit controlling the rate of vapor flow between the evaporator and sorber through the pathway, and being selectively operable to permit, stop and restart the flow of gas through the pathway. The pump may be used with a compartment storing temperature sensitive material. The evaporator may be positioned inside and the sorber outside the compartment, or the sorber may be positioned inside and the evaporator outside the compartment. The pump may be used in an apparatus including both cool and warm compartments, with an insulation layer in each. A method is disclosed for reusing the pump after the sorption material has been sorbed.

Abstract: A connection apparatus for electrically connecting a stored energy source to an electrical device having an electric drive motor, wherein the connection apparatus is part of the stored energy source or of the electrical device and can be connected to a connection apparatus of the electrical device or of the stored energy source, wherein the connection apparatuses have plug contours and counter plug contours, by means of which the stored energy source is interlockingly fastened to the electrical device in a fastening position, in which at least two electrical connections between the electrical device and the stored energy source having different potential, are each established by means of a pair of base contact elements and base counter contact elements of the connection apparatuses, said contact elements being in contact with each other, for the supply of electrical energy to the electrical device by the stored energy source.

Abstract: In one embodiment, a semiconductor device includes a first contact pad disposed at a top side of a workpiece, a second contact pad disposed at the top side of the workpiece. An isolation region is disposed between the first contact pad and the second contact pad. A metal strip is disposed at least partially within the isolation region. The metal strip is not coupled to an external potential node.

Abstract: A connection apparatus for electrically connecting a stored energy source to an electrical device having an electric drive motor, wherein the connection apparatus is part of the stored energy source or of the electrical device and can be connected to a connection apparatus of the electrical device or of the stored energy source, wherein the connection apparatuses have plug contours and counter plug contours, by means of which the stored energy source is interlockingly fastened to the electrical device in a fastening position, in which at least two electrical connections between the electrical device and the stored energy source having different potential, are each established by means of a pair of base contact elements and base counter contact elements of the connection apparatuses, said contact elements being in contact with each other, for the supply of electrical energy to the electrical device by the stored energy source.

Abstract: The present invention relates to blood brain barrier shuttles that bind receptors on the blood brain barrier (R/BBB) and methods of using the same.

Abstract: Herein is reported a method for producing a fusion-polypeptide comprising the seeps of a) cultivating a mammalian cell comprising a nucleic acid encoding a variant fusion-polypeptide wherein the amino acid sequence of the fusion-polypeptide has been modified by replacing in a pro-fusion-polypeptide the endogenous protease cleavage site between the pro-peptide and the fusion-polypeptide with an exogenous (with respect to the origins of the parts of the fusion-polypeptide) or artificial protease cleavage site, and b) recovering the fusion-polypeptide or fusion-pro-polypeptide from the cell or the cultivation median and thereby producing the (recombinant) fusion-polypeptide.

Abstract: Herein is reported a method for producing a fusion-polypeptide comprising the steps of a) cultivating a mammalian cell comprising a nucleic acid encoding a variant fusion-polypeptide wherein the amino acid sequence of the fusion-polypeptide has been modified by replacing in a pro-fusion-polypeptide the endogenous protease cleavage site between the pro-peptide and the fusion-polypeptide with an exogenous (with respect to the origins of the parts of the fusion-polypeptide) or artificial protease cleavage site, and b) recovering the fusion-polypeptide or fusion-pro-polypeptide from the cell or the cultivation medium and thereby producing the (recombinant) fusion-polypeptide.

Abstract: A robot device having a driven unit is proposed, wherein the driven unit is conceived for approaching surfaces. The driven unit according to the present invention is covered with a protective layer from a coating material which is electrically conductive and has a thickness of at least 4 millimeters.

Abstract: A method is provided for operating a dishwasher (1) in the form of a batch dishwasher, which has a treatment chamber (2) for accommodating washware to be cleaned. Provision is made, during an adsorption phase, for air to be conducted out of the treatment chamber (2) through a sorption unit (41), which contains a reversibly dehydratable dry material, in such a way that the dry material absorbs moisture from the air stream, wherein the air is then returned to the treatment chamber (2). Provision is further made, during a desorption phase, for the dry material of the sorption unit (41) to be heated in such a way that moisture is desorbed from the dry material as steam. During the desorption phase, the sorption unit (41) is subjected to forced ventilation only to such an extent that recondensation of desorbed steam in the sorption unit (41) itself is effectively prevented.