Abstract: The present disclosure generally relates to a method for testing a telecommunication standard-based positioning, navigation, and timing system and a test device. The system includes the test device. Radio signals from at least three different transmitters are received by the test device. Each transmitter transmits a radio signal according to the telecommunication standard. An assessed position of the test device is determined based on the radio signals received by the test device. The position of the mobile device is determined by the test device additionally to the assessed position. The assessed position is compared with the determined position.

Abstract: Techniques are described for detecting a specified substance in an examination object by way of a magnetic resonance apparatus. A controller ascertains a magnetic resonance sequence comprising at least one sub-sequence for detecting at least one substance to be detected in the examination object as a function of the at least one substance to be detected, and ascertains at least one measuring instant for capturing a respective MRT signal to detect the at least one substance to be detected in the examination object as a function of the at least one substance to be detected. The at least one MRT signal is evaluated for fulfillment of a predetermined detection condition, and a presence of the at least one substance to be detected is established when the at least one MRT signal fulfils the predetermined detection condition.

Abstract: A coating device for coating a base body, as well as a method. The coating device has at least one holding device for fixing a base body, at least one stamping station and at least one printing station for applying one or more printed layers to at least one partial area of a first surface of the base body and/or to at least one partial area of one or more film elements stamped on the base body and/or to at least one partial area of one or more further printed layers applied to the base body, and in that the stamping station has one or more stamping units for stamping one or more film elements on at least one partial area of a first surface of the base body and/or on at least one partial area of one or more further film elements stamped on the base body and/or on at least one partial area of one or more printed layers applied to the base body.

Abstract: A method of operating a diaphragm valve is specified. The diaphragm valve comprises a fluid housing having a valve seat formed therein, a diaphragm which cooperates with the valve seat to open or close a flow path through the fluid housing, and at least two sensors from the following group: a capacitive sensor, which is arranged such that the diaphragm is located at least in sections in the electric field of the capacitive sensor, a temperature sensor, a pressure sensor, a force sensor, a pH sensor, a stress sensor and a vibration sensor, wherein an index value is formed from the measured values of the different sensors by means of a data fusion algorithm at at least two points in time, wherein a degree of wear of the diaphragm is determined on the basis of a change in the index value. Furthermore, a diaphragm valve is specified.

Abstract: Capturing MR image data of an examination object using an MR apparatus, including: performing a balanced steady-state free precession sequence with phase progress of 180 degrees per repetition time using the MR apparatus; in the balanced steady-state free precession sequence, providing a white-marker gradient in order at least partially to balance a dephasing caused by a magnetic-field-changing object in the examination object; capturing image data of the examination object using the MR apparatus at an echo time; and adjusting a phase development between phase magnetization of a first and second materials, which form an interface in the examination object, in the balanced steady-state free precession sequence using the MR apparatus, wherein due to the adjusting of the phase development before an effect of the white-marker gradient, a co-phasal alignment of a magnetization of the first material and of the second material at the interface is effected at the echo time.

Abstract: A temperature controller for a sorption system having an evaporator to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a flow channel extending between the evaporator and sorber to provide a gas pathway connecting them, a valve to control the rate of gas flow in the flow channel, and a temperature sensor positioned to measure the temperature of an evaporator surface or the air adjacent thereto indicative of an evaporator surface temperature, and generate a temperature signal. The controller includes an inflatable member having first and second inflation states, and a control unit configured to evaluate the temperature signal and in response control the state of inflation of the inflatable member and thereby the operation of the valve to control the rate of gas flow between the evaporator and sorber through the gas pathway.

Abstract: A sorption heat pump having an evaporator containing a working fluid to evaporate the fluid to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a vapor pathway connecting the evaporator and sorber, and a thermal control unit controlling the rate of vapor flow between the evaporator and sorber through the pathway, and being selectively operable to permit, stop and restart the flow of gas through the pathway. The pump may be used with a compartment storing temperature sensitive material. The evaporator may be positioned inside and the sorber outside the compartment, or the sorber may be positioned inside and the evaporator outside the compartment. The pump may be used in an apparatus including both cool and warm compartments, with an insulation layer in each. A method is disclosed for reusing the pump after the sorption material has been sorbed.

Abstract: A thermally insulated transport container for use with an ice battery, having an internal usable volume for freeze-free cooling of temperature-sensitive products placed therein, the usable volume having an outward usable volume portion, an internal cold storage volume sized to receive the ice battery, the cold storage volume having an inward cold storage volume portion adjacent to the outward usable volume portion to define a common interface of the usable volume and the cold storage volume, a heat-conducting liner extending about the usable volume and having a heat-conducting liner portion located between the outward usable volume portion and the inward cold storage volume portion, and a phase change material (PCM) container positioned adjacent to the heat-conducting liner portion at the common interface and in heat-conducting contact with the heat conduction liner portion, the PCM container sized to contain a phase change material.

Abstract: A temperature controller for a sorption system having an evaporator to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a flow channel extending between the evaporator and sorber to provide a gas pathway connecting them, a valve to control the rate of gas flow in the flow channel, and a temperature sensor positioned to measure the temperature of an evaporator surface or the air adjacent thereto indicative of an evaporator surface temperature, and generate a temperature signal. The controller includes an inflatable member having first and second inflation states, and a control unit configured to evaluate the temperature signal and in response control the state of inflation of the inflatable member and thereby the operation of the valve to control the rate of gas flow between the evaporator and sorber through the gas pathway.

Abstract: A sorption heat pump having an evaporator containing a working fluid to evaporate the fluid to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a vapor pathway connecting the evaporator and sorber, and a thermal control unit controlling the rate of vapor flow between the evaporator and sorber through the pathway, and being selectively operable to permit, stop and restart the flow of gas through the pathway. The pump may be used with a compartment storing temperature sensitive material. The evaporator may be positioned inside and the sorber outside the compartment, or the sorber may be positioned inside and the evaporator outside the compartment. The pump may be used in an apparatus including both cool and warm compartments, with an insulation layer in each. A method is disclosed for reusing the pump after the sorption material has been sorbed.

Abstract: A temperature controller for a sorption system having an evaporator to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a flow channel extending between the evaporator and sorber to provide a gas pathway connecting them, a valve to control the rate of gas flow in the flow channel, and a temperature sensor positioned to measure the temperature of an evaporator surface or the air adjacent thereto indicative of an evaporator surface temperature, and generate a temperature signal. The controller includes an inflatable member having first and second inflation states, and a control unit configured to evaluate the temperature signal and in response control the state of inflation of the inflatable member and thereby the operation of the valve to control the rate of gas flow between the evaporator and sorber through the gas pathway.

Abstract: A temperature controller for a sorption system having an evaporator to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a flow channel extending between the evaporator and sorber to provide a gas pathway connecting them, a valve to control the rate of gas flow in the flow channel, and a temperature sensor positioned to measure the temperature of an evaporator surface or the air adjacent thereto indicative of an evaporator surface temperature, and generate a temperature signal. The controller includes an inflatable member having first and second inflation states, and a control unit configured to evaluate the temperature signal and in response control the state of inflation of the inflatable member and thereby the operation of the valve to control the rate of gas flow between the evaporator and sorber through the gas pathway.

Abstract: Herein is reported a method for producing a fusion-polypeptide comprising the seeps of a) cultivating a mammalian cell comprising a nucleic acid encoding a variant fusion-polypeptide wherein the amino acid sequence of the fusion-polypeptide has been modified by replacing in a pro-fusion-polypeptide the endogenous protease cleavage site between the pro-peptide and the fusion-polypeptide with an exogenous (with respect to the origins of the parts of the fusion-polypeptide) or artificial protease cleavage site, and b) recovering the fusion-polypeptide or fusion-pro-polypeptide from the cell or the cultivation median and thereby producing the (recombinant) fusion-polypeptide.

Abstract: A sorption heat pump having an evaporator containing a working fluid to evaporate the fluid to produce a gas, a sorber containing a sorption material to sorb the gas during a sorption phase, a vapor pathway connecting the evaporator and sorber, and a thermal control unit controlling the rate of vapor flow between the evaporator and sorber through the pathway, and being selectively operable to permit, stop and restart the flow of gas through the pathway. The pump may be used with a compartment storing temperature sensitive material. The evaporator may be positioned inside and the sorber outside the compartment, or the sorber may be positioned inside and the evaporator outside the compartment. The pump may be used in an apparatus including both cool and warm compartments, with an insulation layer in each. A method is disclosed for reusing the pump after the sorption material has been sorbed.

Abstract: A connection apparatus for electrically connecting a stored energy source to an electrical device having an electric drive motor, wherein the connection apparatus is part of the stored energy source or of the electrical device and can be connected to a connection apparatus of the electrical device or of the stored energy source, wherein the connection apparatuses have plug contours and counter plug contours, by means of which the stored energy source is interlockingly fastened to the electrical device in a fastening position, in which at least two electrical connections between the electrical device and the stored energy source having different potential, are each established by means of a pair of base contact elements and base counter contact elements of the connection apparatuses, said contact elements being in contact with each other, for the supply of electrical energy to the electrical device by the stored energy source.

Abstract: In one embodiment, a semiconductor device includes a first contact pad disposed at a top side of a workpiece, a second contact pad disposed at the top side of the workpiece. An isolation region is disposed between the first contact pad and the second contact pad. A metal strip is disposed at least partially within the isolation region. The metal strip is not coupled to an external potential node.

Abstract: A connection apparatus for electrically connecting a stored energy source to an electrical device having an electric drive motor, wherein the connection apparatus is part of the stored energy source or of the electrical device and can be connected to a connection apparatus of the electrical device or of the stored energy source, wherein the connection apparatuses have plug contours and counter plug contours, by means of which the stored energy source is interlockingly fastened to the electrical device in a fastening position, in which at least two electrical connections between the electrical device and the stored energy source having different potential, are each established by means of a pair of base contact elements and base counter contact elements of the connection apparatuses, said contact elements being in contact with each other, for the supply of electrical energy to the electrical device by the stored energy source.

Abstract: The present invention relates to blood brain barrier shuttles that bind receptors on the blood brain barrier (R/BBB) and methods of using the same.

Abstract: Herein is reported a method for producing a fusion-polypeptide comprising the seeps of a) cultivating a mammalian cell comprising a nucleic acid encoding a variant fusion-polypeptide wherein the amino acid sequence of the fusion-polypeptide has been modified by replacing in a pro-fusion-polypeptide the endogenous protease cleavage site between the pro-peptide and the fusion-polypeptide with an exogenous (with respect to the origins of the parts of the fusion-polypeptide) or artificial protease cleavage site, and b) recovering the fusion-polypeptide or fusion-pro-polypeptide from the cell or the cultivation median and thereby producing the (recombinant) fusion-polypeptide.

Abstract: Herein is reported a method for producing a fusion-polypeptide comprising the steps of a) cultivating a mammalian cell comprising a nucleic acid encoding a variant fusion-polypeptide wherein the amino acid sequence of the fusion-polypeptide has been modified by replacing in a pro-fusion-polypeptide the endogenous protease cleavage site between the pro-peptide and the fusion-polypeptide with an exogenous (with respect to the origins of the parts of the fusion-polypeptide) or artificial protease cleavage site, and b) recovering the fusion-polypeptide or fusion-pro-polypeptide from the cell or the cultivation medium and thereby producing the (recombinant) fusion-polypeptide.