Patents by Inventor Peter Malcolm Colman

Peter Malcolm Colman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
    Patent number: 8952157
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: February 10, 2015
    Assignees: AbbVie Inc., The Walter and Eliza Hall Institute of Medical Research
    Inventors: Hong Ding, George A. Doherty, Steven W. Elmore, Laura Hexamer, Aaron R. Kunzer, Cheol-Min Park, Xiahong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Le Wang, Michael D. Wendt, Peter Edward Czabotar, Guillaume Laurent Lessene, Peter Malcolm Colman
  • Therapeutic pro-apoptotic BH3-like molecules and methods for generating and/or selecting the same
    Patent number: 8686110
    Abstract: The present invention relates generally to therapeutic molecules which are useful for modulating apoptosis in a target cell or cell population. More particularly, the present invention provides therapeutic agents which inhibit pro-survival molecules and which are capable of inducing or facilitating apoptosis of a target cell or cell population such as cancer cells. The present invention further provides methods for generating or selecting the therapeutic molecules and pharmaceutical compositions comprising the therapeutic molecules.
    Type: Grant
    Filed: June 23, 2006
    Date of Patent: April 1, 2014
    Assignee: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Peter Malcolm Colman, David Ching Siang Huang, Erinna Faith Lee, Walter Douglas Fairlie
  • APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
    Publication number: 20140066621
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: July 26, 2013
    Publication date: March 6, 2014
    Applicants: The Walter and Eliza Hall Institute of Medical Research, AbbVie Inc.
    Inventors: Milan Bruncko, Yujia Dai, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa Hasvold, Laura Hexamer, Aaron R. Kunzer, Robert A. Mantei, Chang H. Park, Cheol-Min Park, Andrew M. Petros, Xiahong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt, Peter Edward Czabotar, Guillaume Laurent Lessene, Peter Malcolm Colman, William J. McClellan
  • BENZOTHIAZOLE COMPOUNDS
    Publication number: 20100197711
    Abstract: The present invention relates to benzothiazole compounds that mimic the activity of BH3 only proteins and are capable of binding to and neutralizing pro survival Bcl 2 proteins. The invention also relates to the use of such compounds in the regulation of cell death or cell survival and the treatment and/or prophylaxis of diseases or conditions associated with the deregulation of cell death or cell survival.
    Type: Application
    Filed: September 27, 2007
    Publication date: August 5, 2010
    Inventors: Keith Geoffrey Watson, Guillaume Laurent Lessene, Jonathan Bayldon Baell, David Ching Siang Huang, Ian Philip Street, Jerry McKee Adams, Peter Malcolm Colman, Brad Edmund Sleebs, Brian John Smith, Peter Edward Czabotar
  • THERAPEUTIC PRO-APOPTOTIC BH3-LIKE MOLECULES AND METHODS FOR GENERATING AND/OR SELECTING THE SAME
    Publication number: 20090048164
    Abstract: The present invention relates generally to therapeutic molecules which are useful for modulating apoptosis in a target cell or cell population. More particularly, the present invention provides therapeutic agents which inhibit pro-survival molecules and which are capable of inducing or facilitating apoptosis of a target cell or cell population such as cancer cells. The present invention further provides methods for generating or selecting the therapeutic molecules and pharmaceutical compositions comprising the therapeutic molecules.
    Type: Application
    Filed: June 23, 2006
    Publication date: February 19, 2009
    Applicant: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Peter Malcolm Colman, David Ching Siang Huang, Erinna Faith Lee, Walter Douglas Fairlie
  • Target binding polypeptide
    Patent number: 5844094
    Abstract: A target-binding polypeptide having (a) a stable core polypeptide region (SCR); and (b) at least one target-binding region (TBR), in which the target-binding region(s) are covalently attached to the SCR and which have optionally been subjected to a maturation step in order to modify the specificity, the affinity or the avidity of binding to the target. The polypeptides may self associate to form stable dimers, aggregates or arrays. The polypeptides of the invention have utility in the diagnostic, therapeutic, predictive or preventative fields of the pharmaceutical and health care industries, as well as more general application in the detection and assay of chemical entities.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: December 1, 1998
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Peter John Hudson, Maria Lah, Alex Andrew Kortt, Robert Alexander Irving, John Leslie Atwell, Robyn Louise Malby, Barbara Elaine Power, Peter Malcolm Colman
  • Derivatives and analogues of 2-deoxy-2,3-didehydro-n-acetyl neuraminic acid and their use as antiviral agents
    Patent number: 5648379
    Abstract: Derivatives and analogues of 2-deoxy-2,3-didehydro-N-acetyl neuraminic acid, pharmaceutical formulations thereof, methods for their preparation and their use in the treatment of viral infections, in particular influenza, are described.
    Type: Grant
    Filed: October 19, 1994
    Date of Patent: July 15, 1997
    Assignee: Biota Scientific Management Pty., Ltd.
    Inventors: Laurence Mark Von Itzstein, Wen-Yang Wu, Tho Van Phan, Basil Danylec, Betty Jin, Peter Malcolm Colman, Joseph Noozhumurry Varghese