Patents by Inventor Peter Markham

Peter Markham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190060070
    Abstract: A partial valve prosthesis includes a framework configured for following a shape of a portion of the native valve annulus when implanted into the native valve annulus, the framework including securement features for anchoring the framework to an inner periphery of the native valve annulus and retaining at least one leaflet configured to replace a corresponding one of the plurality of native leaflets; and at least one leaflet secured to the framework. Additional embodiments and methods are disclosed.
    Type: Application
    Filed: July 16, 2018
    Publication date: February 28, 2019
    Inventors: Adam Groothuis, Adrian Ebner, Peter Markham, Elazer Edelman
  • Patent number: 10022222
    Abstract: The present embodiments relate to systems and methods for treating lumenal valves. Particularly, and in accordance with one aspect, the present disclosure is directed to methods and systems for partial or complete replacement of lumenal valves. An exemplary catheter in accordance with the disclosure includes an elongate body having a proximal end and a distal end, and a retractable sheath mounted on the elongate body proximate the distal end. The sheath and elongate body cooperating to define a first annularly-shaped compartment between the body and sheath. The catheter further includes a valve prosthesis mounted in the compartment, the prosthesis having proximal and distal ends connected to a means for deploying the valve prosthesis from the catheter.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: July 17, 2018
    Inventors: Adam Groothuis, Adrian Ebner, Peter Markham, Elazer R. Edelman
  • Patent number: 8894704
    Abstract: The present embodiments relate to systems and methods for treating lumenal valves. Particularly, and in accordance with one aspect, the present disclosure is directed to methods and systems for partial or complete replacement of lumenal valves. An exemplary catheter in accordance with the disclosure includes an elongate body having a proximal end and a distal end, and a retractable sheath mounted on the elongate body proximate the distal end. The sheath and elongate body cooperating to define a first annularly-shaped compartment between the body and sheath. The catheter further includes a valve prosthesis mounted in the compartment, the prosthesis having proximal and distal ends connected to a means for deploying the valve prosthesis from the catheter.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: November 25, 2014
    Inventors: Adam Groothuis, Adrian Ebner, Peter Markham, Elazer Edelman
  • Publication number: 20130310924
    Abstract: The present embodiments relate to systems and methods for treating lumenal valves. Particularly, and in accordance with one aspect, the present disclosure is directed to methods and systems for partial or complete replacement of lumenal valves. An exemplary catheter in accordance with the disclosure includes an elongate body having a proximal end and a distal end, and a retractable sheath mounted on the elongate body proximate the distal end. The sheath and elongate body cooperating to define a first annularly-shaped compartment between the body and sheath. The catheter further includes a valve prosthesis mounted in the compartment, the prosthesis having proximal and distal ends connected to a means for deploying the valve prosthesis from the catheter.
    Type: Application
    Filed: April 23, 2013
    Publication date: November 21, 2013
    Inventors: Adam Groothuis, Adrian Ebner, Peter Markham, Elazer Edelman
  • Publication number: 20110112630
    Abstract: The present embodiments relate to systems and methods for treating lumenal valves. Particularly, and in accordance with one aspect, the present disclosure is directed to methods and systems for partial or complete replacement of lumenal valves. An exemplary catheter in accordance with the disclosure includes an elongate body having a proximal end and a distal end, and a retractable sheath mounted on the elongate body proximate the distal end. The sheath and elongate body cooperating to define a first annularly-shaped compartment between the body and sheath. The catheter further includes a valve prosthesis mounted in the compartment, the prosthesis having proximal and distal ends connected to a means for deploying the valve prosthesis from the catheter.
    Type: Application
    Filed: October 6, 2010
    Publication date: May 12, 2011
    Inventors: Adam Groothuis, Adrian Ebner, Peter Markham, Elazer R. Edelman
  • Publication number: 20100228280
    Abstract: The invention provides a variety of catheters and methods for using such catheters. An exemplary catheter includes an elongate body having a proximal end a distal end. The elongate body defines a longitudinal axis of the catheter. The exemplary catheter further includes at least one inflatable member disposed on the elongate body proximate the distal end of the elongate body. The interior of the inflatable member is in fluid communication with an inflation lumen in the elongate body. The exemplary catheter also includes a first filter adapted and configured to capture emboli in a patient's bloodstream as the bloodstream passes through the first filter along a first direction. The exemplary catheter further includes a second filter adapted and configured to capture emboli in a patient's bloodstream as the bloodstream passes through the second filter along a second direction, wherein the second direction is generally opposite to the first direction.
    Type: Application
    Filed: March 9, 2009
    Publication date: September 9, 2010
    Inventors: Adam Groothuis, Edward I. McNamara, Peter Markham, Elazer R. Edelman
  • Patent number: 7145014
    Abstract: The invention relates to a process for the preparation of certain quinoline derivatives, in particular, 8-[(4-amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-(3-trifluoromethylphenoxy)quinoline succinate.
    Type: Grant
    Filed: May 2, 2003
    Date of Patent: December 5, 2006
    Assignee: SmithKline Beecham p.l.c.
    Inventors: David Bell, Bryan John Davies, Peter Markham Kincey