Patents by Inventor Peter McLean
Peter McLean has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11957720Abstract: The present invention generally relates to the field of probiotic bacteria. In particular, it relates to methods for treating or preventing functional GI disorders comprising administering Bifidobacterium longum, such as Bifidobacterium longum ATCC BAA-999.Type: GrantFiled: April 27, 2022Date of Patent: April 16, 2024Assignee: Societe des Produits Nestle S.A.Inventors: Peter McLean, Gabriela Bergonzelli Degonda, Stephen Michael Collins, Premysl Bercik, Elena Verdu de Bercik
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Publication number: 20230386632Abstract: Methods and systems for evaluating a query perturbation, in a cell based assay representing a test state, are provided. Control data points having dimensions representing measurements of different features across control cell aliquots are obtained. Test data points having dimensions representing measurements of different features across test cell aliquots are obtained. A composite test vector is computed between measures of central tendency across the control data points and measures of central tendency across the test data points. Query perturbation data points having dimensions representing measurements of different features across perturbation cell aliquots are obtained. A composite query perturbation vector is computed between measures of central tendency across the control data points and measures of central tendency across the plurality of query perturbation data points.Type: ApplicationFiled: July 27, 2023Publication date: November 30, 2023Applicant: Recursion Pharmaceuticals, Inc.Inventors: Mason Victors, Berton Earnshaw, Renat Khaliullin, Blake Borgeson, Peter McLean, Nathan Lazar, Katie-Rose Skelly
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Patent number: 11715551Abstract: Methods and systems for evaluating a query perturbation, in a cell based assay representing a test state, are provided. Control data points having dimensions representing measurements of different features across control cell aliquots are obtained. Test data points having dimensions representing measurements of different features across test cell aliquots are obtained. A composite test vector is computed between measures of central tendency across the control data points and measures of central tendency across the test data points. Query perturbation data points having dimensions representing measurements of different features across perturbation cell aliquots are obtained. A composite query perturbation vector is computed between measures of central tendency across the control data points and measures of central tendency across the plurality of query perturbation data points.Type: GrantFiled: June 18, 2020Date of Patent: August 1, 2023Inventors: Mason Victors, Berton Earnshaw, Renat Khaliullin, Blake Borgeson, Peter McLean, Nathan Lazar, Katie-Rose Skelly
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Patent number: 11452745Abstract: The present invention generally relates to the field of probiotic bacteria. In particular, it relates to methods for treating or preventing functional GI disorders comprising administering Bifidobacterium longum, such as Bifidobacterium longum ATCC BAA-999.Type: GrantFiled: June 29, 2018Date of Patent: September 27, 2022Assignee: Societe des Produits Nestle S.A.Inventors: Peter McLean, Gabriela Bergonzelli Degonda, Stephen Michael Collins, Premysl Bercik, Elena Verdu de Bercik
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Publication number: 20220280576Abstract: The present invention generally relates to the field of probiotic bacteria. In particular, it relates to methods for treating or preventing functional GI disorders comprising administering Bifidobacterium longum, such as Bifidobacterium longum ATCC BAA-999.Type: ApplicationFiled: April 27, 2022Publication date: September 8, 2022Inventors: Peter McLean, Gabriela Bergonzelli Degonda, Stephen Michael Collins, Premysl Bercik, Elena Verdu de Bercik
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Patent number: 11361438Abstract: In various embodiments, an experiment analysis application detects executional artifacts in experiments involving microwell plates. The experiment analysis application computes one or more sets of spatial features based on one or more heat maps associated with a microwell plate. The experiment analysis application then aggregates the set(s) of spatial features to generate a feature vector. The experiment analysis application inputs the feature vector into a trained classifier. In response, the trained classifier generates a label indicating that the microwell plate is associated with a first executional artifact.Type: GrantFiled: July 27, 2020Date of Patent: June 14, 2022Assignee: RECURSION PHARMACEUTICALS, INC.Inventors: Benjamin Marc Feder Fogelson, Peter McLean, Imran Haque, Marissa Saunders, Eric Fish, Charles Baker, Juan Sebastián Rodríguez Vera
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Publication number: 20220027795Abstract: In various embodiments, a training application trains a classifier to detect executional artifacts in experiments involving microwell plates. The training application computes spatial information based on a heat map associated with a microwell plate. The training application then computes a set of features based on the spatial information. Subsequently, the training application executes one or more machine learning operations based, at least in part, on the set of features to generate a trained classifier. The trained classifier classifies sets of features associated with different microwell plates with respect to labels associated with executional artifacts. Advantageously, the trained classier can be used to accurately and consistently detect executional artifacts across different experiments and over time.Type: ApplicationFiled: July 27, 2020Publication date: January 27, 2022Inventors: Benjamin Marc Feder FOGELSON, Peter MCLEAN, Imran HAQUE, Marissa SAUNDERS, Eric FISH, Charles BAKER, Juan Sebastián Rodríguez VERA
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Publication number: 20220028061Abstract: In various embodiments, an experiment analysis application detects executional artifacts in experiments involving microwell plates. The experiment analysis application computes one or more sets of spatial features based on one or more heat maps associated with a microwell plate. The experiment analysis application then aggregates the set(s) of spatial features to generate a feature vector. The experiment analysis application inputs the feature vector into a trained classifier. In response, the trained classifier generates a label indicating that the microwell plate is associated with a first executional artifact.Type: ApplicationFiled: July 27, 2020Publication date: January 27, 2022Inventors: Benjamin Marc Feder FOGELSON, Peter MCLEAN, Imran HAQUE, Marissa SAUNDERS, Eric FISH, Charles BAKER, Juan Sebastián Rodríguez VERA
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Publication number: 20200402628Abstract: Methods and systems for evaluating a query perturbation, in a cell based assay representing a test state, are provided. Control data points having dimensions representing measurements of different features across control cell aliquots are obtained. Test data points having dimensions representing measurements of different features across test cell aliquots are obtained. A composite test vector is computed between measures of central tendency across the control data points and measures of central tendency across the test data points. Query perturbation data points having dimensions representing measurements of different features across perturbation cell aliquots are obtained. A composite query perturbation vector is computed between measures of central tendency across the control data points and measures of central tendency across the plurality of query perturbation data points.Type: ApplicationFiled: June 18, 2020Publication date: December 24, 2020Applicant: Recursion Pharmaceuticals, Inc.Inventors: Mason Victors, Berton Earnshaw, Renat Khaliullin, Blake Borgeson, Peter McLean, Nathan Lazar, Katie-Rose Skelly
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Publication number: 20190134104Abstract: The present invention generally relates to the field of probiotic bacteria. In particular, it relates to methods for treating or preventing functional GI disorders comprising administering Bifidobacterium longum, such as Bifidobacterium longum ATCC BAA-999.Type: ApplicationFiled: June 29, 2018Publication date: May 9, 2019Inventors: Peter McLean, Gabriela Bergonzelli de Gonda, Stephen Michael Collins, Premysl Bercik, Elena Verdu de Bercik
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Patent number: 10028981Abstract: The present invention generally relates to the field of probiotic bacteria. In particular it relates to methods for treating functional GI disorders comprising administering Bifidobacterium longum, such as Bifidobacterium longum ATCC BAA-999.Type: GrantFiled: August 24, 2010Date of Patent: July 24, 2018Assignee: Nestec S.A.Inventors: Peter McLean, Gabriela Bergonzelli de Gonda, Stephen Michael Collins, Premysl Bercik, Elena Verdu de Bercik
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Patent number: 9850145Abstract: A water filtration system with power generating capability includes a membrane that receives relatively hot water on a dirty side, purifies the hot water, and transmits it to a clean side having relatively cold purified water. The system further includes at least one thermoelectric element coupled to the membrane that absorbs thermal energy from the dirty side and emits thermal energy into the clean side to generate electrical power. The system further includes at least one conductor electrically coupled to the at least one thermoelectric element that channels generated electrical power away from the at least one thermoelectric element.Type: GrantFiled: August 13, 2014Date of Patent: December 26, 2017Inventors: Peter McLean Thomas, Rama Venkatasubramanian, Sam Parry, Nancy Jochens, Jerry Morrow
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Publication number: 20170225503Abstract: A security paper is provided that includes at least one layer of fibrous substrate and a security deposit thereon. The at least one layer has a main body of a substantially uniform thickness and at least one aperture and/or zone of reduced thickness. The reduced thickness is non-zero and at least 15% less than the thickness of the main body. The security deposit includes at least one element that partially covers the fibrous substrate exposed in the at least one aperture and/or zone of reduced thickness. Therefore, when the at least one layer is split through its thickness into first and second portions, a hole is provided in the first portion and the at least one element is provided on the fibrous substrate of the second portion. A method of manufacturing the security paper and security documents including the security paper are also provided.Type: ApplicationFiled: April 21, 2017Publication date: August 10, 2017Applicant: DE LA RUE INTERNATIONAL LIMITEDInventors: Peter McLean Henderson, Matthew Charles Sudgon, Georgina Stewart
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Publication number: 20160247996Abstract: KiloWatt-level, large footprint, high power density thermoelectric modules are disclosed for high temperature applications. The thermoelectric modules utilize a compliant interface that reduces thermal mismatch stress and allows thermoelectric devices to be fabricated with dimensions greater than 6×6 cm.Type: ApplicationFiled: February 19, 2016Publication date: August 25, 2016Applicant: Novus Energy Technologies, Inc.Inventors: Peter McLean Thomas, Rama Venkatasubramanian
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Patent number: 9034811Abstract: Concentrated cleaning formulations for removing debris from hard surfaces and textile surfaces. An exemplary formulation includes a mixture of the following chemical components, in specified proportions: glycerin; monopropylene glycol; triethylene glycol methyl ether; a non-ionic surfactant; an emulsifier; soya methyl ester or canola methyl ester, or both; and hydroxypropyl sulfonate; The formulation is free of water other than insignificant amounts present in the chemical components combined to make the mixture. Combining the formulation with water causes a temperature of the combination to increase above the temperatures of the water and the formulation before combining.Type: GrantFiled: November 8, 2013Date of Patent: May 19, 2015Inventors: David Edward Molnar, Peter McLean Harrison
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Publication number: 20150133359Abstract: Concentrated cleaning formulations for removing debris from hard surfaces and textile surfaces. An exemplary formulation includes a mixture of the following chemical components, in specified proportions: glycerin; monopropylene glycol; triethylene glycol methyl ether; a non-ionic surfactant; an emulsifier; soya methyl ester or canola methyl ester, or both; and hydroxypropyl sulfonate; The formulation is free of water other than insignificant amounts present in the chemical components combined to make the mixture. Combining the formulation with water causes a temperature of the combination to increase above the temperatures of the water and the formulation before combining.Type: ApplicationFiled: November 8, 2013Publication date: May 14, 2015Inventors: David Edward Molnar, Peter McLean Harrison
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Publication number: 20150048028Abstract: A water filtration system with power generating capability includes a membrane that receives relatively hot water on a dirty side, purifies the hot water, and transmits it to a clean side having relatively cold purified water. The system further includes at least one thermoelectric element coupled to the membrane that absorbs thermal energy from the dirty side and emits thermal energy into the clean side to generate electrical power. The system further includes at least one conductor electrically coupled to the at least one thermoelectric element that channels generated electrical power away from the at least one thermoelectric element.Type: ApplicationFiled: August 13, 2014Publication date: February 19, 2015Inventors: Peter McLean Thomas, Rama Venkatasubramanian, Sam Parry, Nancy Jochens, Jerry Morrow
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Patent number: 8919821Abstract: The present invention is concerned with providing security substrates, and documents made therefrom, such as banknotes, with features for visual inspection by members of the public. More specifically the invention relates to a novel security substrate containing at least two elongate security elements for the purposes of public and non-public verification. The security substrate comprises a substrate and at least two elongate security elements each having a width of less than or equal to 6 mm. The security elements are at least partially embedded within the substrate and running substantially parallel to each other with a gap therebetween of no greater than 10 mm. The total cross-directional width of a zone occupied by the two security elements and the gap is less than or equal to 18 mm.Type: GrantFiled: January 17, 2005Date of Patent: December 30, 2014Assignee: De La Rue International LimitedInventors: Duncan Hamilton Reid, Gerald Sidney Payne, Paul Howland, Peter McLean Henderson
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Patent number: 8268128Abstract: The invention is directed toward improvements in security substrates, such as paper, used for making security documents, such as bank notes, having anti-counterfeit able features and in particular to security substrates incorporating an elongate security element and methods of making the substrate. The invention comprises a security substrate for making security documents and the like comprising a fibrous base substrate and an elongate security element at least partially embedded therein. At one surface of the security substrate one portion of the security element is exposed to provide a continuous track along the length of the security element. A plurality of other portions along at least one edge of the security element are partially covered by overlapping regions of the fibrous substrate. The invention further comprises a method of manufacturing such a security substrate.Type: GrantFiled: March 27, 2009Date of Patent: September 18, 2012Assignee: De la Rue International LimitedInventors: Peter McLean Henderson, Christian David Paul Clark
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Publication number: 20120230956Abstract: The present invention generally relates to the field of probiotic bacteria. In particular it relates to Bifidobacterium longum, such as Bifidobacterium longum ATCC BAA-999, and its use in ingestible compositions. The composition described in the present invention may be used to treat or prevent functional GI disorders.Type: ApplicationFiled: August 24, 2010Publication date: September 13, 2012Applicant: NESTEC S.A.Inventors: Peter McLean, Gabriela Bergonzelli de Gonda, Stephen Michael Collins, Premysl Bercik, Elena Verdu de Bercik