Patents by Inventor Peter Melnyk

Peter Melnyk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for detecting phosphomonoester
    Patent number: 8101375
    Abstract: The invention provides a method of modifying a phosphomonoester moiety of a target compound. The method can include the steps of (a) providing a target compound having an electrophilic moiety and a phosphomonoester moiety; (b) contacting the target compound with a first carbodiimide compound under conditions for preferential addition of the first carbodiimide compound to the electrophilic moiety over the phosphomonoester moiety, thereby forming an electrophile-protected target compound; and (c) contacting the electrophile-protected target compound with a second carbodiimide compound and a nucleophilic compound under conditions for addition of the nucleophilic compound to the phosphomonoester.
    Type: Grant
    Filed: August 25, 2010
    Date of Patent: January 24, 2012
    Assignee: Illumina, Inc.
    Inventors: Igor Kozlov, Peter Melnyk, Chanfeng Zhao
  • COMPOSITIONS AND METHODS FOR DETECTING PHOSPHOMONOESTER
    Publication number: 20110020853
    Abstract: The invention provides a method of modifying a phosphomonoester moiety of a target compound. The method can include the steps of (a) providing a target compound having an electrophilic moiety and a phosphomonoester moiety; (b) contacting the target compound with a first carbodiimide compound under conditions for preferential addition of the first carbodiimide compound to the electrophilic moiety over the phosphomonoester moiety, thereby forming an electrophile-protected target compound; and (c) contacting the electrophile-protected target compound with a second carbodiimide compound and a nucleophilic compound under conditions for addition of the nucleophilic compound to the phosphomonoester.
    Type: Application
    Filed: August 25, 2010
    Publication date: January 27, 2011
    Applicant: Illumina, Inc.
    Inventors: Igor Kozlov, Peter Melnyk, Chanfeng Zhao
  • Compositions and methods for detecting phosphomonoester
    Patent number: 7803751
    Abstract: The invention provides a method of modifying a phosphomonoester moiety of a target compound. The method can include the steps of (a) providing a target compound having an electrophilic moiety and a phosphomonoester moiety; (b) contacting the target compound with a first carbodiimide compound under conditions for preferential addition of the first carbodiimide compound to the electrophilic moiety over the phosphomonoester moiety, thereby forming an electrophile-protected target compound; and (c) contacting the electrophile-protected target compound with a second carbodiimide compound and a nucleophilic compound under conditions for addition of the nucleophilic compound to the phosphomonoester.
    Type: Grant
    Filed: December 9, 2005
    Date of Patent: September 28, 2010
    Assignee: Illumina, Inc.
    Inventors: Igor Kozlov, Peter Melnyk, Chanfeng Zhao
  • COMPOSITIONS AND METHODS FOR DETECTING PROTEASE ACTIVITY
    Publication number: 20070254301
    Abstract: The invention provides a method of determining activity of a protease.
    Type: Application
    Filed: May 3, 2007
    Publication date: November 1, 2007
    Applicant: Illumina, Inc.
    Inventors: Igor Kozlov, Peter Melnyk
  • Compositions and methods for detecting phosphomonoester
    Publication number: 20070134723
    Abstract: The invention provides a method of modifying a phosphomonoester moiety of a target compound. The method can include the steps of (a) providing a target compound having an electrophilic moiety and a phosphomonoester moiety; (b) contacting the target compound with a first carbodiimide compound under conditions for preferential addition of the first carbodiimide compound to the electrophilic moiety over the phosphomonoester moiety, thereby forming an electrophile-protected target compound; and (c) contacting the electrophile-protected target compound with a second carbodiimide compound and a nucleophilic compound under conditions for addition of the nucleophilic compound to the phosphomonoester.
    Type: Application
    Filed: December 9, 2005
    Publication date: June 14, 2007
    Applicant: Illumina, Inc.
    Inventors: Igor Kozlov, Peter Melnyk, Chanfeng Zhao
  • Compositions and methods for detecting protease activity
    Patent number: 7229769
    Abstract: The invention provides a method of determining activity of a protease.
    Type: Grant
    Filed: March 25, 2005
    Date of Patent: June 12, 2007
    Assignee: Illumina, Inc.
    Inventors: Igor Kozlov, Peter Melnyk
  • Compositions and methods for detecting protease activity
    Publication number: 20060216721
    Abstract: The invention provides a method of determining activity of a protease.
    Type: Application
    Filed: March 25, 2005
    Publication date: September 28, 2006
    Applicant: Illumina, Inc.
    Inventors: Igor Kozlov, Peter Melnyk