Patents by Inventor Peter Michael Broad

Peter Michael Broad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vivo assays for modulators of sterol biosynthesis
    Patent number: 6828092
    Abstract: A method for the identification of agents which modulate sterol biosynthesis which method comprises contacting a test compound with a host cell comprising a DNA sequence which controls expression of a yeast acetoacetyl CoA thiolase gene operably linked to a reporter system such that modulation of sterol biosynthesis in the host cell leads to a detectable change in cell phenotype, and determining whether any such detectable change has occurred.
    Type: Grant
    Filed: January 12, 1998
    Date of Patent: December 7, 2004
    Assignee: Astrazeneca UK Limited
    Inventors: Graham Keith Dixon, Peter Michael Broad, David John Scanlon
  • Identification of compounds modulating protein/cell membrane association
    Patent number: 5776675
    Abstract: A method for identifying compounds which modulate protein/cell membrane association which method comprises contacting a test compound with a cell, having (i) a cell membrane, (ii) a heterologous protein comprising a reporter sequence and a recognition sequence for cell membrane association, (iii) a reporter system which is acted upon by the reporter sequence such that there is a measurable change in cell phenotype upon modulation of protein/cell membrane association by the test compound, and detecting any change in cell phenotype.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: July 7, 1998
    Assignee: Zeneca Limited
    Inventor: Peter Michael Broad