Abstract: A server system configured to communicate with a device that is installable in a vehicle, such as a portable or in-built navigation device, comprises a communications resource for receiving vehicle data indicative of a parameter of the vehicle; and a processing resource operable to obtain weather data and to process the weather data and the vehicle data to determine at least one weather-related condition in dependence on both the weather data and the vehicle data.

Abstract: A server arranged to process GPS data to generate enhanced map data is disclosed, and comprises a plurality of navigable segments representing segments of a navigable route in an area covered by a map, the server connected with a wireless telecommunications transceiver arranged to receive GPS fixes by wireless telecommunication from a plurality of navigation devices and send the received GPS fixes to the server, the server comprising a processor arranged to generate at least one speed profile for each segment from the GPS fixes from at least two of the plurality of navigation devices, each speed profile comprising an expected speed of travel through the segment, and the server arranged to subsequently cause the transceiver to send the speed profiles to the navigation devices.

Abstract: A server system configured to communicate with a device that is installable in a vehicle, such as a portable or in-built navigation device, comprises a communications resource for receiving vehicle data indicative of a parameter of the vehicle; and a processing resource operable to obtain weather data and to process the weather data and the vehicle data to determine at least one weather-related condition in dependence on both the weather data and the vehicle data.

Abstract: A server arranged to process GPS data to generate enhanced map data is disclosed. The enhanced map data includes a plurality of navigable segments representing segments of a navigable route in an area covered by a map. In at least one embodiment, the server is connected with a wireless telecommunications transceiver arranged to receive GPS fixes by wireless telecommunication from a plurality of navigation devices and send the received GPS fixes to the server, the server includes a processor arranged to generate at least one speed profile for each segment from the GPS fixes from at least two of the plurality of navigation devices, each speed profile comprising an expected speed of travel through the segment, and the server is arranged to subsequently cause the transceiver to send the speed profiles to the navigation devices.

Abstract: A server system 150 for providing data to at least one mobile device 200, the server system comprising a processing resource 174. In a first embodiment, the processing resource 174 is configured to generate contour data representing a boundary of a respective area for which a weather-related parameter has substantially the same value, the contour data being sent to a mobile device 200. In a second embodiment, the processing resource 174 is configured to determine a plurality of parameter values of a model representative of weather-related data, and to filter the parameter values such that only some of the values of sent to a mobile device 200.

Abstract: A server system configured to communicate with a device that is installable in a vehicle, such as a portable or in-built navigation device, comprises a communications resource for receiving vehicle data indicative of a parameter of the vehicle; and a processing resource operable to obtain weather data and to process the weather data and the vehicle data to determine at least one weather-related condition in dependence on both the weather data and the vehicle data.

Abstract: A process for detecting cells from a sample, comprising the following steps: (a) applying the sample or a fraction of the sample in liquid phase in a direction of flow to a porous, generally two-dimensional support with pores having on the surface thereof at least one binding molecule specific for the cells to be detected or for fragments of such cells; (b) allowing the cells to be detected or of fragments of such cells to enter from the sample or sample fraction into the pores of said porous, generally two-dimensional support, said pores having such a mean pore size that the cells or fragments to be detected are able to enter into the pores; (c) retaining the cells or fragments to be detected by at least one binding molecule specific for the cells or fragments to be detected; (d) performing an optical read-out method on said substantially two-dimensional support by an imaging method, optionally after the cells or cell fragments to be detected have been labeled with a labeling agent; wherein (e) the optica

Abstract: A method of processing data relating to an electronic map, the map comprising a plurality of segments representing navigable segments in the area covered by the map, the method comprising using a processing apparatus to generate segment data and comprising the steps of: collecting historic travel data for the segment; defining a jam condition for the segment, such that where the jam condition is satisfied the segment is classified as jammed and otherwise as not jammed; generating a jam probability for the segment according to the historic travel data and the jam condition definition; generating a jam speed for the segment using the historic travel data, the jam speed being indicative of the speed on the segment when the segment is considered jammed; and associating the jam probability and the jam speed with the segment in the electronic map.

Abstract: A method of generating expected average speeds of travel across one or more segments in the area covered by an electronic map, each segment representing a navigable segment in the area covered by the map and having associated therewith: an average speed of travel across that segment; segment data comprising at least one jam probability, the jam probability indicating the likelihood of a jam on that segment; and a jam speed indicative of the speed of travel on that segment when it is considered jammed. The method comprises using the segment data to predict whether a jam condition exists on at least one or each of the segments; and outputting the expected average speed of travel across these segments as: a) a first speed, where a jam condition is predicted to exist, the first speed being the jam speed for the relevant segment or a speed based thereon, or b) a second speed, where a jam condition is not predicted, the second speed being the average speed for the relevant segment or a speed based thereon.

Abstract: A navigation apparatus 200 comprises a processing resource 260 configured to: determine a route to a selected destination; obtain weather-related data; and modify speed data for a plurality of route segments in dependence on the weather-related data. For each route there is a respective classifier that classifies the road type for the route segment, and the processing resource is configured to modify the speed data for each route segment based on the weather-related data and the road type represented by the classifier for that route segment.

Abstract: An in vitro process for the preparation of antibodies of the IgG type, comprising the steps of: i. challenging dendritic cells obtained from a donor with an antigen against which the antibodies to be prepared are directed; ii. challenging CD4+ T cells obtained from the same donor with fragments of the antigen presented by the dendritic cells from step L, with the proviso that the dendritic cells are ones essentially not secreting interferon-? (IFN-?) and interleukin 12 (IL-12), to generate antigen-specific CD4+ Th2 cells; iii. challenging with the antigen a B cell population obtained from the same donor and including a sufficient proportion of naive B cells; and iv. contacting the antigen-specific CD4+ Th2 cells according to ii. with at least a fraction of the B cell population from iii. to form an antigen-specific plasma cell; v. immortalizing said antigen-specific plasma cell; and vi. isolating the IgG antibodies formed by said antigen-specific plasma cell.

Abstract: The invention relates to a method for selectively detecting and/or quantifying superparamagnetic and/or ferromagnetic particles on analytes. The method is characterized in that a frequency component of magnetic fields (15, 18), which is generated due to the non-linearity of the magnetization characteristic curve of the particles, is measured at a mixing frequency. A device for selectively detecting and/or quantifying superparamagnetic and/or ferromagnetic particles on analytes comprises: a container (12) that contains particles, which are to be detected and/or quantified, on analytes; at least one oscillator (13, 16; 25) for generating frequencies of alternating magnetic fields (15, 18); at least one field generator (14, 17) for subjecting the analytes to alternating magnetic fields (15, 18); a magnetic field sensor (20) for measuring a response magnetic field (19) of the particles, and; at least one phase-sensitive detector (21, 23).

Abstract: A method of creating a speed estimation representative of vehicle speed along one or more road segments. In at least one embodiment, the method includes obtaining at least reference speed data from a reference source of data and second speed data from a second source of data, wherein the second source is different from the reference and the speed data is indicative of vehicle speed along the or each road segment; using the reference speed data to verify the second speed data and modifying the second speed data according to the verification; and generating an estimation of vehicle speed for the or each road segment based upon the verified second speed data.

Abstract: A method of creating map data is disclosed, the map data including a plurality of navigable segments representing segments of a navigable route in the area covered by the map with each segment being arranged to have speed data associated therewith. In at least one embodiment, the method includes processing speed data relating to a plurality of the segments of the navigable route covered by the map to generate a set of generated speed profiles, with each generated speed profile within the set being an approximation to traffic speed along one or more of the segments of the navigable route and each speed profile varying with respect to time; and associating at least one speed profile from the set with a navigable segment within the map data.

Abstract: A method of processing speed data is disclosed for use in the provision of enhanced map data including a plurality of navigable segments which together may define a navigable route in an area covered by a digital map.

Abstract: A method of processing positioning data to create map data is disclosed, the map data including a plurality of navigable segments representing segments of a navigable route in the area covered by the map with each segment being arranged to have speed data associated therewith. In at least one embodiment, the method includes processing the speed data to categorise the speed data into a plurality of time periods for the navigable segment with which the speed data is associated; and averaging the speed data within each time period in order to generate a measured speed profile for the navigable segment.

Abstract: A server arranged to process GPS data to generate enhanced map data is disclosed. The enhanced map data includes a plurality of navigable segments representing segments of a navigable route in an area covered by a map. In at least one embodiment, the server is connected with a wireless telecommunications transceiver arranged to receive GPS fixes by wireless telecommunication from a plurality of navigation devices and send the received GPS fixes to the server, the server includes a processor arranged to generate at least one speed profile for each segment from the GPS fixes from at least two of the plurality of navigation devices, each speed profile comprising an expected speed of travel through the segment, and the server is arranged to subsequently cause the transceiver to send the speed profiles to the navigation devices.

Abstract: A method is disclosed, for processing positioning data to generate map data which includes a plurality of navigable segments representing segments of a navigable route in the area covered by the map, with each segment being arranged to have speed data associated therewith.

Abstract: A method of providing a graphical indication of traffic congestion along a stretch of physical road notionally divided by a traffic information provider into one or more road segments is disclosed. The invention also covers a navigation system, portable navigation device, and or software capable of implementing such a method.

Abstract: The invention relates to a method for selectively detecting and/or quantifying superparamagnetic and/or ferromagnetic particles on analytes. The method is characterized in that a frequency component of magnetic fields (15, 18), which is generated due to the non-linearity of the magnetization characteristic curve of the particles, is measured at a mixing frequency. A device for selectively detecting and/or quantifying superparamagnetic and/or ferromagnetic particles on analytes comprises: a container (12) that contains particles, which are to be detected and/or quantified, on analytes; at least one oscillator (13, 16; 25) for generating frequencies of alternating magnetic fields (15, 18); at least one field generator (14, 17) for subjecting the analytes to alternating magnetic fields (15, 18); a magnetic field sensor (20) for measuring a response magnetic field (19) of the particles, and; at least one phase-sensitive detector (21, 23).