Patents by Inventor Peter Model

Peter Model has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tamper-proof closure/seal for containers, particularly wine bottles
    Publication number: 20050258129
    Abstract: In the present invention the bottle or container to be secured is provided with a plastic sleeve with a clear plastic top, providing a view of a safety capsule. The plastic sleeve may be provided with small holes, allowing air to enter within the air space underneath the plastic sleeve. The safety capsule is kept in place with an attachment point to the plastic sleeve. If any tampering occurs such as using an injection needle to enter the bottle through the cork, the safety capsule may be punctured, casing its color to change (e.g., from white to red). This color change is a warning to the end user and seller that a toxic attack to the contents may have occurred.
    Type: Application
    Filed: May 21, 2004
    Publication date: November 24, 2005
    Inventor: Peter Model
  • Methods of preforming homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof
    Publication number: 20050210539
    Abstract: A simple method for modifying genes in a recombination deficient host cell is disclosed. Such modifications include generating insertions, deletions, substitutions, and/or point mutations at any chosen site in the independent origin based cloning vector. The modified gene is contained in an independent origin based cloning vector that is used to introduce a modified heterologous gene into a cell. Such a modified vector may be used in the production of a germline transmitted transgenic animal, or in gene targeting protocols in eukaryotic cells. In particular, high throughput methodology is provided for generating the modified the independent origin based cloning vectors of the present invention.
    Type: Application
    Filed: November 22, 2004
    Publication date: September 22, 2005
    Inventors: Nathaniel Heintz, Peter Model, Xiangdong Yang, Shiaoching Gong
  • Methods of performing homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof
    Patent number: 6821759
    Abstract: A simple method for modifying genes in a recombination deficient host cell is disclosed. Such modifications include generating insertions, deletions, substitutions, and/or point mutations at any chosen site in the independent origin based cloning vector. The modified gene is contained in an independent origin based cloning vector that is used to introduce a modified heterologous gene into a cell. Such a modified vector may be used in the production of a germline transmitted transgenic animal, or in gene targeting protocols in eukaryotic cells. In particular, high throughput methodology is provided for generating the modified the independent origin based cloning vectors of the present invention.
    Type: Grant
    Filed: July 19, 2000
    Date of Patent: November 23, 2004
    Assignee: The Rockefeller University
    Inventors: Nathaniel Heintz, Peter Model, Xiangdong W. Yang, Shiaoching Gong
  • Methods of performing homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof
    Patent number: 6143566
    Abstract: A simple method for modifying genes in a recombination deficient host cell is disclosed. Such modifications include generating insertion, deletions, substitutions, and/or point mutations at any chosen site in the independent origin based cloning vector. The modified gene can be contained in an independent origin based cloning vector that is used to introduce a modified heterologous gene into a cell. Such a modified vector may be used in the production of a germline transmitted transgenic animal, or in gene targeting protocols in eukaryotic cells.
    Type: Grant
    Filed: June 23, 1997
    Date of Patent: November 7, 2000
    Assignee: The Rockfeller University
    Inventors: Nathaniel Heintz, Peter Model, Xiangdong W. Yang
  • Method for facilitating externalization of proteins synthesized in bacteria
    Patent number: 4595658
    Abstract: A method of externalizing proteins from the periplasmic space of gram-negative bacteria and in particular, E. coli and its relatives, comprising utilizing bacteria which have a phage gene, coding for a protein (such as gene III protein) or a mutant bacterial gene (such as a gene coding for a membrane function) which causes perturbation of the outer bacterial membrane resulting in leakage of proteins in the periplasmic space from the cell.
    Type: Grant
    Filed: September 13, 1982
    Date of Patent: June 17, 1986
    Assignee: The Rockefeller University
    Inventors: Norman D. Zinder, Peter Model, Jef D. Boeke