Patents by Inventor Peter Mouritzen

Peter Mouritzen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11111535
    Abstract: The invention relates to nucleic acid probes, nucleic acid probe libraries, and kits for detecting, classifying, or quantitating components in a complex mixture of nucleic acids, such as a transcriptome, and methods of using the same. The invention also relates to methods of identifying nucleic acid probes useful in the probe libraries and to methods of identifying a means for detection of a given nucleic acid.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: September 7, 2021
    Assignee: QIAGEN GmbH
    Inventors: Niels B. Ramsing, Peter Mouritzen, Søren Morgenthaler Echwald, Niels Tolstrup
  • Patent number: 10400288
    Abstract: The present application concerns a new in vitro method for assessing the risk that a subject suffers from prostate cancer.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: September 3, 2019
    Assignees: Aarhus Universitet, Region Midtjylland, QIAGEN GmbH
    Inventors: Anni Rønfeldt Thomsen, Jacob Christian Fredsøe, Karina Dalsgaard Sørensen, Lars Kongsbak, Peter Mouritzen, Torben Ørntoft
  • Patent number: 10358681
    Abstract: The present application concerns a new in vitro method for assessing the prognosis of a prostate cancer patient, comprising measuring the expression level of at least two miRs selected from group of miRs consisting of: miR-106a-5p, miR-10b-5p, miR-133a-3p, mi R-152-3p, miR-185-5p, miR-193a-5p, miR-221-3p, miR-23a-3p, miR-30d-3p, miR-326, mi R-374b-5p, miR-615-3p and mi R-625-3p in a RNA sample from prostate cells obtained from said patient, wherein a changed expression level of said at least 2 miRs, as compared to a reference expression profile, is indicative of the prognosis of said prostate cancer patient.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: July 23, 2019
    Assignees: Aarhus Universitet, Region Midtjylland, QIAGEN GmbH
    Inventors: Anni Rønfeldt Thomsen, Helle Kristensen, Karina Dalsgaard Sørensen, Lars Kongsbak, Peter Mouritzen, Torben Ørntoft
  • Publication number: 20180044737
    Abstract: The present application concerns a new in vitro method for assessing the prognosis of a prostate cancer patient, comprising measuring the expression level of at least two miRs selected from group of miRs consisting of: miR-106a-5p, miR-10b-5p, miR-133a-3p, miR-152-3p, miR-185-5p, miR-193a-5p, miR-221-3p, miR-23a-3p, miR-30d-3p, miR-326, miR-374b-5p, miR-615-3p and miR-625-3p in a RNA sample from prostate cells obtained from said patient, wherein a changed expression level of said at least 2 miRs, as compared to a reference expression profile, is indicative of the prognosis of said prostate cancer patient.
    Type: Application
    Filed: February 26, 2016
    Publication date: February 15, 2018
    Applicant: Exiqon A/S
    Inventors: Anni RØNFELDT THOMSEN, Helle KRISTENSEN, Karina DALSGAARD SØRENSEN, Lars KONGSBAK, Peter MOURITZEN, Torben ØRNTOFT
  • Publication number: 20180030542
    Abstract: The present application concerns a new in vitro method for assessing the risk that a subject suffers from prostate cancer.
    Type: Application
    Filed: February 5, 2016
    Publication date: February 1, 2018
    Inventors: Anni RØNFELDT THOMSEN, Jacob Christian FREDSØE, Karina DALSGAARD SØRENSEN, Lars KONGSBAK, Peter MOURITZEN, Torben ØRNTOFT
  • Publication number: 20170081719
    Abstract: The invention relates to nucleic acid probes, nucleic acid probe libraries, and kits for detecting, classifying, or quantitating components in a complex mixture of nucleic acids, such as a transcriptome, and methods of using the same. The invention also relates to methods of identifying nucleic acid probes useful in the probe libraries and to methods of identifying a means for detection of a given nucleic acid.
    Type: Application
    Filed: September 23, 2016
    Publication date: March 23, 2017
    Inventors: Niels B. RAMSING, Peter MOURITZEN, Søren Morgenthaler ECHWALD, Niels TOLSTRUP
  • Patent number: 8383344
    Abstract: The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.
    Type: Grant
    Filed: June 1, 2009
    Date of Patent: February 26, 2013
    Assignee: Exiqon A/S
    Inventors: Nana Jacobsen, Lars Kongsbak, Sakari Kauppinen, Søren Morgenthaler Echwald, Peter Mouritzen, Peter Stein Nielsen, Mikkel Nørholm
  • Patent number: 8293684
    Abstract: The present invention relates to labeling kits containing novel non-natural nucleotide monomers and to methods of making and using such compounds. The invention further relates to a method of detecting the presence of a nucleic acid, e.g., RNA, of interest in a sample, the method having the following steps: providing the sample; ligating a nucleic acid of interest with a labeling reagent according to the instant invention; providing a nucleic acid array having probes directed to the nucleic acid of interest; hybridizing the labeled nucleic acid fragments to said nucleic acid array; and determining the extent of hybridization to said probes to determine the presence of the nucleic acid of interest.
    Type: Grant
    Filed: November 29, 2007
    Date of Patent: October 23, 2012
    Assignee: Exiqon
    Inventors: Peter Mouritzen, Christian Lomholt, Søren Morgenthaler Echwald, Mikkel Noerholm
  • Patent number: 8192937
    Abstract: The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: June 5, 2012
    Assignee: Exiqon A/S
    Inventors: Nana Jacobsen, Lars Kongsbak, Sakari Kauppinen, Søren Morgenthaler Echwald, Peter Mouritzen, Peter Stein Nielsen, Mikkel Nørholm
  • Publication number: 20110076675
    Abstract: The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.
    Type: Application
    Filed: June 1, 2009
    Publication date: March 31, 2011
    Applicant: EXIQON A/S
    Inventors: Nana Jacobsen, Lars Kongsbak, Sakari Kauppinen, Søren Morgenthaler Echwald, Peter Mouritzen, Peter Stein Nielsen, Mikkel Nørholm
  • Publication number: 20090023221
    Abstract: The invention relates to ribonucleic acids and oligonucleotide probes useful for detection and analysis of microRNA precursors and their targets. The invention furthermore relates to oligonucleotide probes for detection and analysis of other non-coding RNAs, mRNAs, mRNA splice variants, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease, such as cancer.
    Type: Application
    Filed: May 16, 2007
    Publication date: January 22, 2009
    Applicant: Exigon A/S
    Inventors: Gregor Obernosterer, Nina Stahlberg, Soren Moller, Soren M. Echwald, Peter Mouritzen, Peter S. Nielsen, Mikkel Norholm, Kim Bundvig Barken
  • Publication number: 20090023594
    Abstract: The present invention relates to labelling kits containing novel non-natural nucleotide monomers and to methods of making and using such compounds. The invention further relates to a method of detecting the presence of a nucleic acid, e.g., RNA, of interest in a sample, the method having the following steps: providing the sample; ligating a nucleic acid of interest with a labelling reagent according to the instant invention; providing a nucleic acid array having probes directed to the nucleic acid of interest; hybridizing the labelled nucleic acid fragments to said nucleic acid array; and determining the extent of hybridization to said probes to determine the presence of the nucleic acid of interest.
    Type: Application
    Filed: November 29, 2007
    Publication date: January 22, 2009
    Applicant: EXIQON A/S
    Inventors: Peter Mouritzen, Christian Lomholt, Soren Morgenthaler Echwald, Mikkel Noerholm
  • Publication number: 20060166238
    Abstract: The invention relates to nucleic acid probes, nucleic acid probe libraries, and kits for detecting, classifying, or quantifying components in a complex mixture of nucleic acids, such as a transcriptome, and methods of using the same. The invention also relates to methods of identifying nucleic acid probes useful in the probe libraries and to methods of identifying a means for detection of a given nucleic acid.
    Type: Application
    Filed: December 21, 2005
    Publication date: July 27, 2006
    Inventors: Niels Ramsing, Peter Mouritzen, Soren Echwald, Niels Tolstrup
  • Publication number: 20060014183
    Abstract: The invention relates to probes which are extendable useful as PCR probes and in probe libraries. The invention further relates to prevention of replication of a primer extension product in PCR reactions.
    Type: Application
    Filed: June 10, 2005
    Publication date: January 19, 2006
    Inventors: Henrik Pfundheller, Michael Meldgaard, Peter Mouritzen, Peter Nielsen, Mikkel Norholm, Soren Echwald
  • Publication number: 20050272075
    Abstract: The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.
    Type: Application
    Filed: April 7, 2005
    Publication date: December 8, 2005
    Inventors: Nana Jacobsen, Lars Kongsbak, Sakari Kauppinen, Soren Echwald, Peter Mouritzen, Peter Nielsen, Mikkel Norholm
  • Publication number: 20050089889
    Abstract: The invention relates to nucleic acid probes, nucleic acid probe libraries, and kits for detecting, classifying, or quantitating components in a complex mixture of nucleic acids, such as a transcriptome, and methods of using the same. The invention also relates to methods of identifying nucleic acid probes useful in the probe libraries and to methods of identifying a means for detection of a given nucleic acid.
    Type: Application
    Filed: June 18, 2004
    Publication date: April 28, 2005
    Inventors: Niels Ramsing, Peter Mouritzen, Soren Echwald, Niels Tolstrup