Patents by Inventor Peter N. Devreotes

Peter N. Devreotes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterotrimeric G-protein
    Patent number: 7691564
    Abstract: Receptor mediated activation of heterotrimeric G-proteins is visualized in living cells by monitoring fluorescence resonance energy transfer (FRET) between subunits of a G protein fused to cyan and yellow fluorescent proteins. The G-protein heterotrimer rapidly dissociates and reassociates upon addition and removal of cognate ligand. Energy transfer pairs of G-proteins enables direct in situ detection and have applications for drug screening and GPCR de-orphaning.
    Type: Grant
    Filed: January 3, 2006
    Date of Patent: April 6, 2010
    Assignee: The Johns Hopkins University
    Inventors: Peter N. Devreotes, Chris Janetopoulos
  • Receptor mediated activation of heterotrimeric G-proteins
    Publication number: 20020048811
    Abstract: Receptor mediated activation of heterotrimeric G-proteins is visualized in living cells by monitoring fluorescence resonance energy transfer (FRET) between subunits of a G protein fused to cyan and yellow fluorescent proteins. The G-protein heterotrimer rapidly dissociates and reassociates upon addition and removal of cognate ligand. Energy transfer pairs of G-proteins enables direct in situ detection and have applications for drug screening and GPCR de-orphaning.
    Type: Application
    Filed: January 19, 2001
    Publication date: April 25, 2002
    Inventors: Peter N. Devreotes, Chris Janetopoulos