Abstract: The invention relates to a device for the thermal or thermo-chemical treatment, more particularly calcination, of material (12), more particularly battery cathode material (14), comprising a housing (16), in which a process space (20) is located. The material (12), or carrying structures (40) loaded with the material (12), can be conveyed in a conveying direction (30) into or through the process space (20) by means of a conveying system (28). A process space atmosphere (50) prevailing in the process space (20) can be heated by means of a heating system (48). There is a process gas system (64), by means of which a process gas (66) can be fed to the process space (20), said process gas being required for the thermal treatment of the material (12).

Abstract: The present invention relates to a method for producing a recombinant polypeptide of interest in a microbial host cell, comprising (a) introducing a polynucleotide encoding the polypeptide of interest into a microbial host cell which has been modified such that an enzymatic activity selected from the group consisting of ketol-acid reductoisomerase (NADP(+)) activity (EC 1.1.1.86), acetohydroxyacid synthase activity (EC 2.2.1.6), aspartate kinase activity (EC 2.7.2.4), homoserine dehydrogenase activity (EC 1.1.1.3), and L-threonine dehydratase activity (EC 4.3.1.19) is modulated in said microbial host cell as compared to the enzymatic activity in an unmodified microbial host cell, and (b) expressing said polypeptide of interest in said microbial host cell. Moreover, the present invention relates to a method for reducing misincorporation of at least one non-canonical branched-chain amino acid into a recombinant polypeptide of interest expressed in a microbial host cell.

Abstract: Information relating to a subset of images within a set of images is received. The information includes metadata of each image. The subset of images are selected from the set of images based upon each image in the subset of images being acquired within a bounding area surrounding a geographical position of a current image. Weight information is received. The weight information controls weights to be given to a plurality of different measures of similarities. A plurality of combined measures of similarity for pairs of images in the subset of images are calculated.

Abstract: The present invention relates to a method for navigating through a set of images depicting a scenery, said method comprising: receiving information relating to a subset of images within said set of images, said information comprising metadata of each image, said subset of images comprising images being acquired from a geographical position, which is within a bounding area surrounding the geographical position of a current image within the set of images; receiving weight information, said weight information controlling weights to be given to a plurality of different measures of similarities based on different types of metadata; and calculating a plurality of combined measures of similarity for pairs of images in the subset of images, said calculating being performed using said metadata and said weight information.

Abstract: A method for producing from host cells a heterologous polypeptide or protein comprising at least one cysteine residue in a reduced state. The method cultured the host cells in a culture medium comprising a reducing agent; and recovered the heterologous polypeptide or protein comprising at least one cysteine residue in a reduced state from the host cells or from the culture medium, where the host cells comprise a nucleic acid encoding the heterologous protein or polypeptide, and where the reducing agent is capable of permeating the plasma membrane of the host cells.

Abstract: The present invention relates to a method for navigating through a set of images depicting a scenery, said method comprising: receiving information relating to a subset of images within said set of images, said information comprising metadata of each image, said subset of images comprising images being acquired from a geographical position, which is within a bounding area surrounding the geographical position of a current image within the set of images; receiving weight information, said weight information controlling weights to be given to a plurality of different measures of similarities based on different types of metadata; and calculating a plurality of combined measures of similarity for pairs of images in the subset of images, said calculating being performed using said metadata and said weight information.

Abstract: A method for navigating through a set of images depicting a scene comprises providing a graph representation of correlations of the images and receiving input for navigation that includes an indication of a current image and weight information to control weights to be given to a plurality of measures of similarities of edges in the graph. The indication of the current image is used to determine a current node in the graph representation. At least one best ranked transition image is determined related to the current image by an edge from the current node, said determining comprising using the weight information to weigh the plurality of measures of similarities for forming a combined measure of similarity for edges from the current node, and selecting the at least one best ranked transition image based on a comparison of the combined measure of similarity for the edges from the current node.

Abstract: A method for navigating through a set of images depicting a scene comprises: providing a graph representation of correlations of the images; receiving input for navigation through the set of images, said input comprising an indication of a current image in the set of images and weight information to control weights to be given to a plurality of measures of similarities of edges in the graph; accessing the graph representation, wherein the indication of the current image is used to determine a current node in the graph representation; and determining at least one best ranked transition image that is related to the current image by an edge from the current node, said determining comprising using the weight information to weigh the plurality of measures of similarities for forming a combined measure of similarity for edges from the current node; and selecting the at least one best ranked transition image based on a comparison of the combined measure of similarity for the edges from the current node.

Abstract: The present invention provides a method for improving the preparation and use of growth media by the uses of specific pellet formulations, which especially are tablets of different sizes, which contain the growth medium or parts thereof and are sterilized with the standard methods of pharmaceutical technology. Specifically these pellet formulations are applied to control a cell culture in a way that the adaptation phase is shorter or that the growth is controlled by a release of certain components at a certain time and in a certain concentration during the process, and nutrients (e.g., nitrogen) can be packed into the cultivation vessel in amounts sufficient for high cell densities without the risk of intoxication of the organism.

Abstract: A method for producing from host cells a heterologous polypeptide or protein comprising at least one cysteine residue in a reduced state. The method cultured the host cells in a culture medium comprising a reducing agent; and recovered the heterologous polypeptide or protein comprising at least one cysteine residue in a reduced state from the host cells or from the culture medium, where the host cells comprise a nucleic acid encoding the heterologous protein or polypeptide, and where the reducing agent is capable of permeating the plasma membrane of the host cells.

Abstract: A method for producing from host cells a heterologous polypeptide or protein comprising at least one cysteine residue in a reduced state. The method cultured the host cells in a culture medium comprising a reducing agent; and recovered the heterologous polypeptide or protein comprising at least one cysteine residue in a reduced state from the host cells or from the culture medium, where the host cells comprise a nucleic acid encoding the heterologous protein or polypeptide, and where the reducing agent is capable of permeating the plasma membrane of the host cells.

Abstract: In a method for controlling the growth of microbes grown in a medium to high cell-densities by the fed-batch technology, a two-phase system, having a liquid phase (cultivation medium) and a solid or gel phase, the solid or gel phase provides a source of substrate-delivering polymer which is turned by an enzyme in a controlled way into a growth-limiting substrate or pH adjusting agent. Also described is a method for restricting the synthesis of growth-limiting metabolites and preventing oxygen-depletion in microbial cell cultures.

Abstract: The present invention is generally in the field of continuous and high-cell-density cultivation in laboratory- or large-scale liquid shaken cultures. More particularly it relates to a method of enzyme-based fed-batch (EnBase) for liquid microbial prokaryotic or eukaryotic cell cultivation having the possibility to manipulate the growth rate of the cultured organisms by a controlled enzymatic release of the growth-limiting substrate-monomer from substrate-polymers or substrate-oligomers.

Abstract: The invention relates to an enzymatic method for the enantioselective reduction of organic keto compounds to the corresponding chiral hydroxy compounds, an alcohol dehydrogenase from Lactobacillus minor and a method for the enantioselective production of (S)-hydroxy compounds from a racemate.

Abstract: A method for producing from host cells a heterologous polypeptide or protein comprising at least one cysteine residue in a reduced state. The method cultured the host cells in a culture medium comprising a reducing agent; and recovered the heterologous polypeptide or protein comprising at least one cysteine residue in a reduced state from the host cells or from the culture medium, where the host cells comprise a nucleic acid encoding the heterologous protein or polypeptide, and where the reducing agent is capable of permeating the plasma membrane of the host cells.

Abstract: The present invention is generally in the field of continuous and high-cell-density cultivation in laboratory- or large-scale liquid shaken cultures. More particularly it relates to a method of enzyme-based fed-batch (EnBase) for liquid microbial prokaryotic or eukaryotic cell cultivation having the possibility to manipulate the growth rate of the cultured organisms by a controlled enzymatic release of the growth-limiting substrate-monomer from substrate-polymers or substrate-oligomers.

Abstract: The present invention provides a method for improving the preparation and use of growth media by the uses of specific pellet formulations, which especially are tablets of different sizes, which contain the growth medium or parts thereof and are sterilized with the standard methods of pharmaceutical technology. Specifically these pellet formulations are applied to control a cell culture in a way that the adaptation phase is shorter or that the growth is controlled by a release of certain components at a certain time and in a certain concentration during the process, and nutrients (e.g., nitrogen) can be packed into the cultivation vessel in amounts sufficient for high cell densities without the risk of intoxication of the organism.

Abstract: In a method for controlling the growth of microbes grown in a medium to high cell-densities by the fed-batch technology, a two-phase system, having a liquid phase (cultivation medium) and a solid or gel phase, the solid or gel phase provides a source of substrate-delivering polymer which is turned by an enzyme in a controlled way into a growth-limiting substrate or pH adjusting agent. Also described is a method for restricting the synthesis of growth-limiting metabolites and preventing oxygen-depletion in microbial cell cultures.

Abstract: The invention relates to an enzymatic method for the enantioselective reduction of organic keto compounds to the corresponding chiral hydroxy compounds, an alcohol dehydrogenase from Lactobacillus minor and a method for the enantioselective production of (S)-hydroxy compounds from a racemate.

Abstract: The invention concerns a method for the detection of bacteria of the genus Legionella using a sandwich hybridization procedure at temperatures between 50 and 55° C. According to the invention new oligonucleotide probes are utilized as capture and detection probes enabling a genus or species specific detection of different Legionella bacteria. Advantageous is the exchangeability of capture and detection probes against each other for genus or species specific detections of Legionella bacteria. Furthermore the detection procedure can be performed with combinations of oligonucleotide probes for a genus and species specific detection.