Abstract: The present invention generally relates to novel protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides. The present invention also relates to polynucleotides encoding such protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides of the invention, and to methods of using these protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides in the treatment of disease.

Abstract: Devices and methods for detecting one or more characteristics of cells with patch clamp electrodes, wherein the used patch clamp electrodes are cleaned by application of ultrasonic vibrations.

Abstract: The disclosure relates to a switching element comprising an external part and an internal part, which is axially displaceable in a bore of the external part. At least one radially displaceable locking element is disposed within at least one receptacle of the internal part and includes a flattened portion on a radially outwardly directed end. At least one recess of the external part can be acted upon by a control pressure and the at least one locking element can thereby be radially displaced from the locking position into a release position. At least in a respective locking position, a chamber delimited by the at least one locking element is spatially separated from the at least one recess of the external part by a respective locking section. At least one bypass is designed, which indirectly fluidly connects the at least one recess of the external part and a respective chamber.

Abstract: The present application relates to a novel and efficient process with high yield for preparing methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate of the formula (I) in the crystalline form of modification I, wherein the x-ray diffractogram of the compound of the formula (I) in modification exhibits peak maxima of the 2 theta angle at 5.9, 6.9, 22.7, in very high purity which is significantly more cost-effective than the process known from the art and can be performed in customary pilot- and production plant-equipment (stirred tank/devices for isolation).

Abstract: A support rail and housing assembly is mountable on a housing base. The housings are equipped with electrical contact and/or functional elements which can be strung together. The support rail is mountable on the mounting base even when the housings have already been arranged on the support rail before the support rail is mounted. The support rail is secured to the mounting base by two or more mounting pins which have been placed before the support rail is mounted to the mounting base. The mounting pins and the support rail are designed to correspond to each other such that the support rail can be placed on the mounting pins and locked thereto without using a tool.

Abstract: Embodiments of the present disclosure may provide a data protection system that performs identification of errors from queries on a database. The data protection system can further identify corrupted data from additional errors, are difficult to detect, and occur between layers of data in the database system. The data protection system can perform corrections of the error data by rebuilding database data or removing the corrupted data.

Abstract: A dynamic broadcast system as well as a terminal and a control device for use in such a dynamic broadcast system are presented. Transmission parameters, transmission times and transmission paths used for broadcasting and providing content, either via a broadcast network or a broadband network to terminals used in the dynamic broadcast system are dynamically controlled. Further, a decision logic is provided that dynamically decides transmission parameters, transmission times and transmission paths used for broadcasting and providing content based on monitoring data carrying information on user specific content usage and/or transmission quality data carrying information on the quality of a transmission link between a broadband server and a terminal and/or of a reception of content broadcast by a broadcast transmitter.

Abstract: A dynamic broadcast system as well as a terminal and a control device for use in such a dynamic broadcast system are presented. Transmission parameters, transmission times and transmission paths used for broadcasting and providing content, either via a broadcast network or a broadband network to terminals used in the dynamic broadcast system are dynamically controlled. Further, a decision logic is provided that dynamically decides transmission parameters, transmission times and transmission paths used for broadcasting and providing content based on monitoring data carrying information on user specific content usage and/or transmission quality data carrying information on the quality of a transmission link between a broadband server and a terminal and/or of a reception of content broadcast by a broadcast transmitter.

Abstract: A wind stop device for motor vehicles having improved stability. The wind stop device comprising a wind blocker having a wind blocker frame extending transversely to a vehicles longitudinal axis. The device further comprising a flow-hindering element closing a frame opening of the wind blocker frame, wherein the wind blocker is foldable about a wind blocker-folding axis by way of at least one hinge. The device further comprising a cover pivotally connected to the wind blocker about a pivot axis and having a cover frame extending transversely to a vehicles longitudinal axis and extending away from the pivot axis. The flow-hindering element closing a frame opening of the cover frame, wherein the cover frame is foldable about a cover folding axis by way of at least one hinge, where the hinges can have a blocking device to prevent the cover frame from folding.

Abstract: A dynamic broadcast system as well as a terminal and a control device for use in such a dynamic broadcast system are presented. Transmission parameters, transmission times and transmission paths used for broadcasting and providing content, either via a broadcast network or a broadband network to terminals used in the dynamic broadcast system are dynamically controlled. Further, a decision logic is provided that dynamically decides transmission parameters, transmission times and transmission paths used for broadcasting and providing content based on monitoring data carrying information on user specific content usage and/or transmission quality data carrying information on the quality of a transmission link between a broadband server and a terminal and/or of a reception of content broadcast by a broadcast transmitter.

Abstract: A wind stop device for motor vehicles having improved stability. The wind stop device comprising a wind blocker having a wind blocker frame extending transversely to a vehicles longitudinal axis. The device further comprising a flow-hindering element closing a frame opening of the wind blocker frame, wherein the wind blocker is foldable about a wind blocker-folding axis by way of at least one hinge. The device further comprising a cover pivotally connected to the wind blocker about a pivot axis and having a cover frame extending transversely to a vehicles longitudinal axis and extending away from the pivot axis. The flow-hindering element closing a frame opening of the cover frame, wherein the cover frame is foldable about a cover folding axis by way of at least one hinge, where the hinges can have a blocking device to prevent the cover frame from folding.

Abstract: A dynamic broadcast system as well as a terminal and a control device for use in such a dynamic broadcast system are presented. Transmission parameters, transmission times and transmission paths used for broadcasting and providing content, either via a broadcast network or a broadband network to terminals used in the dynamic broadcast system are dynamically controlled. Further, a decision logic is provided that dynamically decides transmission parameters, transmission times and transmission paths used for broadcasting and providing content based on monitoring data carrying information on user specific content usage and/or transmission quality data carrying information on the quality of a transmission link between a broadband server and a terminal and/or of a reception of content broadcast by a broadcast transmitter.

Abstract: In a wind deflector for installation in a vehicle roof in a front area, comprising a wind deflector body which extends in a direction of extension transversely to a direction of travel, a lifting device, with which the wind deflector body can be moved between a position retracted into the vehicle roof and a position extended out of the vehicle roof and projecting beyond a contour of the upper side of the vehicle roof and thus deflecting wind, wherein the lifting device has at least one lifting unit with a mounting base and a lifting arm which is mounted with a lifting arm bearing for pivoting about a first pivot axis relative to the mounting base and engages on the wind deflector body at an end located opposite the lifting arm bearing, in order to achieve a reliable movability of the wind deflector body with devices which are as mechanically simple as possible it is suggested that an actuating unit which is supported on the mounting base and engages on the lifting arm be provided for moving the lifting arm an

Abstract: A device determines trip information related to a route travelled by a passenger. In order to provide a solution for automatically verifying trip information and for enhancing passenger comfort when using public transportation, the device includes a receiver that can be carried by the passenger and receives a signal generated by a ground-based local transmitter, and a processor for determining at least one bit of trip information by signal evaluation in which at least one signal characteristic of a received signal is evaluated.

Abstract: In a wind deflector for installation in a vehicle roof in a front area, comprising a wind deflector body which extends in a direction of extension transversely to a direction of travel, a lifting device, with which the wind deflector body can be moved between a position retracted into the vehicle roof and a position extended out of the vehicle roof and projecting beyond a contour of the upper side of the vehicle roof and thus deflecting wind, wherein the lifting device has at least one lifting unit with a mounting base and a lifting arm which is mounted with a lifting arm bearing for pivoting about a first pivot axis relative to the mounting base and engages on the wind deflector body at an end located opposite the lifting arm bearing, in order to achieve a reliable movability of the wind deflector body with devices which are as mechanically simple as possible it is suggested that an actuating unit which is supported on the mounting base and engages on the lifting arm be provided for moving the lifting arm an

Abstract: A dynamic broadcast system as well as a terminal and a control device for use in such a dynamic broadcast system are presented. Transmission parameters, transmission times and transmission paths used for broadcasting and providing content, either via a broadcast network or a broadband network to terminals used in the dynamic broadcast system are dynamically controlled. Further, a decision logic is provided that dynamically decides transmission parameters, transmission times and transmission paths used for broadcasting and providing content based on monitoring data carrying information on user specific content usage and/or transmission quality data carrying information on the quality of a transmission link between a broadband server and a terminal and/or of a reception of content broadcast by a broadcast transmitter.