Abstract: Devices, systems, and methods are provided for enhanced geographical caching of estimated arrival times. A method may include receiving respective user inputs indicative of respective users being in transit to a destination location from within a geographic region; determining, for the first user and the second user, a first estimated time of arrival from a first geographical area to the destination location, the first geographical area including the first location and the second location; identifying a third location of the first device at a third time, wherein the third location is within the first geographical area; determining that a time-to-live (TTL) of the first estimated time of arrival has not expired at the third time; and refraining from recalculating the first estimated time of arrival.

Abstract: Devices, systems, and methods of the present disclosure are directed to facilitating control of a graphical user interface associated with performing a medical procedure. Inputs can be received from a plurality of input devices interacting with respective sets of input options displayed on respective portions of the graphical user interface. One of the input devices can be operable by a physician, during a medical procedure, to navigate a set of input options to modify a graphical representation of at least one of a medical device and an anatomic structure displayed on the graphical user interface.

Abstract: Compounds of general formula (I): wherein R1, R2, R3, R4, R5a, R5b X1, X2, Z and Y are as defined herein are positive modulators of the calcium-activated chloride channel (CaCC), TMEM16A. The compounds are useful for treating diseases and conditions affected by modulation of TMEM16A, particularly respiratory diseases and conditions.

Abstract: The technology disclosed herein enables ambient noise level determination at an endpoint using a secondary audio capture system for the endpoint. In a particular embodiment, a method includes during a communication session, receiving an audio signal representing sound captured by a secondary audio capture system for an endpoint on the communication session. A primary audio capture system for the endpoint captures voice communications from a user of the endpoint for the communication session. The method further determining an ambient noise level for the endpoint from the audio signal and, in response to determining that the ambient noise level satisfies a loudness criterion, presenting a notification to the user about the ambient noise level.

Abstract: The present invention relates to novel compounds of general Formula II: wherein the groups X, and R1 to R4 have the meanings given in the description, to a process for preparing these compounds and to their use for treating, preventing or ameliorating viral infections and diseases which are associated with PLA2G16.

Abstract: Compounds of general formula (I): wherein R1, R2, R3, R4, R5a, R* X1, X2, Z and Y are as defined herein are positive modulators of the calcium-activated chloride channel (CaCC), TMEM16A. The compounds are useful for treating diseases and conditions affected by modulation of TMEM16A, particularly respiratory diseases and conditions.

Abstract: The technology disclosed herein enables ambient noise level determination at an endpoint using a secondary audio capture system for the endpoint. In a particular embodiment, a method includes during a communication session, receiving an audio signal representing sound captured by a secondary audio capture system for an endpoint on the communication session. A primary audio capture system for the endpoint captures voice communications from a user of the endpoint for the communication session. The method further determining an ambient noise level for the endpoint from the audio signal and, in response to determining that the ambient noise level satisfies a loudness criterion, presenting a notification to the user about the ambient noise level.

Abstract: The present invention relates to novel compounds of general formula (I) wherein the groups X, and R1 to R4 have the meanings given in the description and claims, process for preparing these compounds and their use as for treating, preventing or ameliorating viral infections and their use for treating, preventing or ameliorating diseases which are associated with PLA2G16.

Abstract: Devices, systems, and methods of the present disclosure are directed to facilitating control of a graphical user interface associated with performing a medical procedure. Inputs can be received from a plurality of input devices interacting with respective sets of input options displayed on respective portions of the graphical user interface. One of the input devices can be operable by a physician, during a medical procedure, to navigate a set of input options to modify a graphical representation of at least one of a medical device and an anatomic structure displayed on the graphical user interface.

Abstract: There is provided an aqueous seaweed extract in the form of a solution concentrate composition comprising: (a) at least 0.5% by weight soluble alginate based on the weight of concentrate composition; (b) at least 0.1% calcium by weight based on the weight of concentrate composition; (c) a calcium-chelating agent; and (d) a borate compound.

Abstract: A mounting arrangement 10 for mounting a dog guard 12 in a vehicle. The mounting arrangement 10 includes a bracket part 22 mountable to the dog guard 12. The bracket part 22 includes an opening 30 with a concave contact surface 34 around the opening 30. A fixing member 36 is provided threadably mountable to the end of a bar 52 which extends through the opening 30. The fixing member 36 has a sleeve 44 with a lower convex annular contact surface 48 engageable against the bracket part contact surface 34. The other end of the bar 52 is engageable with for instance a fixing hook provided on the floor of the boot of a car.

Abstract: The present invention relates to novel compounds of general formula (I) wherein the groups X, and R1 to R4 have the meanings given in the description and claims, process for preparing these compounds and their use as for treating, preventing or ameliorating viral infections and their use for treating, preventing or ameliorating diseases which are associated with PLA2G16.

Abstract: A mounting arrangement 10 for mounting a dog guard 12 in a vehicle. The mounting arrangement 10 includes a bracket part 22 mountable to the dog guard 12. The bracket part 22 includes an opening 30 with a concave contact surface 34 around the opening 30. A fixing member 36 is provided threadably mountable to the end of a bar 52 which extends through the opening 30. The fixing member 36 has a sleeve 44 with a lower convex annular contact surface 48 engageable against the bracket part contact surface 34. The other end of the bar 52 is engageable with for instance a fixing hook provided on the floor of the boot of a car.

Abstract: Devices, systems, and methods of the present disclosure are directed to facilitating control of a graphical user interface associated with performing a medical procedure. Inputs can be received from a plurality of input devices interacting with respective sets of input options displayed on respective portions of the graphical user interface. One of the input devices can be operable by a physician, during a medical procedure, to navigate a set of input options to modify a graphical representation of at least one of a medical device and an anatomic structure displayed on the graphical user interface.

Abstract: Devices, systems, and methods of the present disclosure are directed to facilitating control of a graphical user interface associated with performing a medical procedure. Inputs can be received from a plurality of input devices interacting with respective sets of input options displayed on respective portions of the graphical user interface. One of the input devices can be operable by a physician, during a medical procedure, to navigate a set of input options to modify a graphical representation of at least one of a medical device and an anatomic structure displayed on the graphical user interface.

Abstract: There is provided an aqueous seaweed extract in the form of a solution concentrate composition comprising: (a) at least 0.5% by weight soluble alginate based on the weight of concentrate composition; (b) at least 0.1% calcium by weight based on the weight of concentrate composition; (c) a calcium-chelating agent; and (d) a borate compound.

Abstract: This invention provides a method of improving mood and learning capacity in a mammal by giving the mammal a meal of low protein food, followed by a second meal of high glycemic index carbohydrate. A composition to be given to a mammal to improve mood and learning capacity and to reduce aggressive behavior contains at least one tyrosine uptake competitive amino acid in a ratio of 0.5% to 2% to protein. The tyrosine competitive amino acid preferred is leucine, isoleucine or valine.

Abstract: This invention provides a method of improving mood and learning capacity in a mammal by giving the mammal a meal of low protein food, followed by a second meal of high glycemic index carbohydrate. A composition to be given to a mammal to improve mood and learning capacity and to reduce aggressive behavior contains at least one tyrosine uptake competitive amino acid in a ratio of 0.5% to 2% to protein. The tyrosine competitive amino acid preferred is leucine, isoleucine or valine.

Abstract: Apparatus for converting kinetic energy into usable power (200), comprises a frame (204) arranged to be fixed in a vehicle running track (202) and a plurality of plates (211 to 219 inclusive, and 221 to 229 inclusive) mounted to the frame. Each plate being movable in relation to the frame so as to drive an energy conversion means (232, 234). The energy conversion means has a rotating member (293 in FIG. 19) having variable inertia.

Abstract: A content enhancement system and method for increasing search engine visibility is disclosed. Landing web pages are optimized for relevant keywords and phrases associated with e-content publications such as articles, papers, reports, newsletters, etc. Landing web pages may be generated for portions of documents that are sold individually. Landing pages are generated using content description data (including keyword data) for each document portion or content section that will be the subject of a landing page. The content description data is stored in a database. A template defines the layout and appearance of the content description data that is used to generate each landing page. Each landing page includes an optional link to a product purchase page at the publisher's web site that allows a user to purchase the product described on the landing page. Search engines index each of the landing pages making it easier for web users to locate the publisher's products.