Abstract: Embodiments of the present disclosure may include a method for planning and performing an interventional procedure on a patient, the method including steps of providing an augmented reality system, a tracked instrument, a first image acquisition system, a second image acquisition system, and a computer system with a processor and a memory, the tracked instrument having a plurality of sensors to provide a tracked instrument dataset, the first image acquisition system, and the computer system in communication with the augmented reality system, the tracked instrument, the first image acquisition system, and the second image acquisition system. Embodiments may also include acquiring, by the first image acquisition system, the first holographic image dataset from the patient. Embodiments may also include acquiring, by the second image acquisition system, the second holographic image dataset from the patient.

Abstract: A vascular access guidance platform provides enhanced visualization and accuracy for medical procedures through an integrated extended reality system. The platform comprises an extended reality visualization system configured to display three-dimensional holograms overlaid on patient anatomy, a registration and tracking system for spatial alignment between virtual and physical anatomy, multiple imaging sensors including infrared cameras and ultrasound devices, and a processing system with coordinate transformation algorithms. The system captures anatomical imaging data, generates augmented representations of vascular anatomy, and aligns these representations with physical patient anatomy using registration techniques including optical markers, spatial mapping, and bony landmark registration. The platform maintains real-time tracking capabilities throughout procedures, accommodating patient movement and practitioner repositioning.

Abstract: Embodiments of the present disclosure may include a method for planning and performing an interventional procedure on a patient, the method including steps of providing an augmented reality system, a tracked instrument, a first image acquisition system, a second image acquisition system, and a computer system with a processor and a memory, the tracked instrument having a plurality of sensors to provide a tracked instrument dataset, the first image acquisition system, and the computer system in communication with the augmented reality system, the tracked instrument, the first image acquisition system, and the second image acquisition system. Embodiments may also include acquiring, by the first image acquisition system, the first holographic image dataset from the patient. Embodiments may also include acquiring, by the second image acquisition system, the second holographic image dataset from the patient.

Abstract: A system and method for performing a medical procedure on a location of interest of a patient includes a first imaging system, a second imaging system, a computer system, and an augmented reality display system. The first imaging system can be configured to acquire a first image and the second imaging system can be configured to acquire a second image of the location of interest. The computer system can be configured to register the first image and the second image, establish a spatial correlation between the first image, the second image, and the patient, and generate a holographic visualization combining the first image and the second image. The augmented reality display system can be configured to project the holographic visualization and align the first image and the second image with the patient.

Abstract: A prosthetic heart valve includes a collapsible and expandable stent extending in a longitudinal direction between an inflow end and an outflow end, the stent including a plurality of struts defining a plurality of cells, and a plurality of commissure attachment features disposed on the stent, each commissure attachment feature having a first end, a second end opposite the first end, and at least two bodies connected via one or more suspension struts, each of the at least two bodies having at least one eyelet.

Abstract: A system for image-guided intervention of a patient is provided. The system can include an endoluminal probe, a tracking system, a display system, and a registration system. The endoluminal probe can be configured to acquire a real-time image of an internal site within the patient. The tracking system can be configured to track a position and an orientation of the endoluminal probe. The display system can be configured to display the real-time image acquired by the endoluminal probe. The registration system can be configured to register the real-time image from the endoluminal probe with a preoperative image of the internal site. The display system can overlay the registered real-time image from the endoluminal probe with the preoperative image to assist in navigation and intervention at the internal site.

Abstract: A method for performing a procedure on a patient includes acquiring a three-dimensional image of a location of interest on the patient and a two-dimensional image of the location of interest can be acquired. A computer system can relate the three-dimensional image with the two-dimensional image to form a holographic image dataset. The computer system can register the holographic image dataset with the patient. The augmented reality system can render a hologram based on the holographic image dataset from the patient. The hologram can include a projection of the three-dimensional image and a projection of the two-dimensional image. The practitioner can view the hologram with the augmented reality system and perform the procedure on the patient. The practitioner can employ the augmented reality system to visualize a point on the projection of the three-dimensional image and a corresponding point on the projection of the two-dimensional image during the procedure.

Abstract: A method for performing a procedure on a patient includes acquiring a three-dimensional image of a location of interest on the patient and a two-dimensional image of the location of interest can be acquired. A computer system can relate the three-dimensional image with the two-dimensional image to form a holographic image dataset. The computer system can register the holographic image dataset with the patient. The augmented reality system can render a hologram based on the holographic image dataset from the patient. The hologram can include a projection of the three-dimensional image and a projection of the two-dimensional image. The practitioner can view the hologram with the augmented reality system and perform the procedure on the patient. The practitioner can employ the augmented reality system to visualize a point on the projection of the three-dimensional image and a corresponding point on the projection of the two-dimensional image during the procedure.

Abstract: Ways to register an anatomical feature of a patient using augmented reality are provided. Included is a system for registration of an anatomical feature of a patient, the system having an imaging system, a tracked instrument, an augmented reality system, and a computer system. The imaging system can be configured to image the patient and generate an imaging dataset. The tracked instrument can be configured to generate a tracked instrument dataset. The augmented reality system can be configured to display an imaging volume hologram in augmented reality. The computer system can be in communication with the augmented reality system, the imaging system, and the tracked instrument. The computer system can generate an imaging volume dataset based on a first axial plane and a second axial plane, can render the imaging volume dataset into the imaging volume hologram, and can project the image volume hologram in an augmented reality.

Abstract: The present disclosure includes methods for improving surgical precision and outcomes in medical procedures through the use of an augmented reality system. The method involves generating a preoperative plan by visualizing a holographic representation of a patient's anatomy within an augmented reality environment, recording procedure data based on the preoperative plan, updating the augmented reality system using the recorded data, and applying the updated system to establish a continuous improvement feedback loop. This approach enhances surgical accuracy and patient outcomes by integrating real-time data feedback into the surgical process, thereby optimizing surgical procedures and promoting continuous improvement in medical practices.

Abstract: A method of assembling a prosthetic heart valve includes providing a collapsible and expandable stent having an annulus section and an aortic section. The annulus section has a first diameter in a relaxed condition and a second diameter less than the first diameter in a collapsed condition. A constraint is applied to the stent to constrain the annulus section to a predetermined diameter between the first and second diameters. Applying a cuff and/or a plurality of leaflets to the stent in the constrained condition enables less material to be used. The resultant prosthetic valve is therefore able to be collapsed to a smaller diameter for introduction into a patient.

Abstract: Embodiments of the present disclosure may include a method for planning and performing an interventional procedure on a patient, the method including steps of providing an augmented reality system, a tracked instrument, a first image acquisition system, a second image acquisition system, and a computer system with a processor and a memory, the tracked instrument having a plurality of sensors to provide a tracked instrument dataset, the first image acquisition system, and the computer system in communication with the augmented reality system, the tracked instrument, the first image acquisition system, and the second image acquisition system. Embodiments may also include acquiring, by the first image acquisition system, the first holographic image dataset from the patient. Embodiments may also include acquiring, by the second image acquisition system, the second holographic image dataset from the patient.

Abstract: Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.

Abstract: Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.

Abstract: A method for performing a procedure on a patient includes acquiring a three-dimensional image of a location of interest on the patient and a two-dimensional image of the location of interest can be acquired. A computer system can relate the three-dimensional image with the two-dimensional image to form a holographic image dataset. The computer system can register the holographic image dataset with the patient. The augmented reality system can render a hologram based on the holographic image dataset from the patient. The hologram can include a projection of the three-dimensional image and a projection of the two-dimensional image. The practitioner can view the hologram with the augmented reality system and perform the procedure on the patient. The practitioner can employ the augmented reality system to visualize a point on the projection of the three-dimensional image and a corresponding point on the projection of the two-dimensional image during the procedure.

Abstract: A prosthetic heart valve includes a collapsible and expandable stent extending in a longitudinal direction between an inflow end and an outflow end, the stent including a plurality of struts defining a plurality of cells, and a plurality of commissure attachment features disposed on the stent, each commissure attachment feature having a first end, a second end opposite the first end, and at least two bodies connected via one or more suspension struts, each of the at least two bodies having at least one eyelet.

Abstract: A prosthetic heart valve includes a collapsible and expandable stent and a plurality of commissure features disposed on the stent. A collapsible and expandable valve assembly includes a plurality of leaflets connected to the plurality of commissure features, each commissure feature including a body having a proximal end and a distal end. A plurality of eyelets is arranged in rows and columns on the body for distributing load from the plurality of leaflets.

Abstract: An occluder device for occluding a gap between a medical device and adjacent body tissue includes a conformable body having a hollow interior, a leading end and a trailing end; and a port disposed at the trailing end of the body and in fluid communication with the interior of the body.

Abstract: Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.

Abstract: Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.