Abstract: An assembly comprising: two ceramic bodies, which are joined by means of a joint of an active hard solder, or braze, wherein the active hard solder, or braze, has a continuous core volume, which is spaced, in each case, from the ceramic bodies by at least 1 ?m, and an average composition CK with a liquidus temperature Tl(CK), wherein the composition CK has a coefficient of thermal expansion ?(CK), wherein ?(CK)=m·?(K), wherein m?1.5, especially m?1.3 and preferably m?1.2, wherein ?(K) is the average coefficient of thermal expansion of the ceramic material of the ceramic bodies, wherein the joint has boundary layers, which border on the ceramic body, wherein at least one of the boundary layers, which lies outside of the core volume, has an average composition CB with a liquidus temperature Tl(CB), which lies not less than 50 K, preferably not less than 100 K, and especially preferably not less than 200 K, under the liquidus temperature Tl(CK) of the average composition CK of the core volume.

Abstract: This disclosure provides a novel pharmaceutical composition for delivering steroid hormones to a patient in need thereof.

Abstract: The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein are injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection) and/or be molded flexibly into a tissue void of any shape and/or size. In some embodiments, the composition described herein comprises a plurality of silk fibroin particles, which can retain their original volume within the tissue for a period of time. The compositions can be used as a filler to replace a tissue void, e.g., for tissue repair and/or augmentation, or as a scaffold to support tissue regeneration and/or reconstruction. In some embodiments, the compositions described herein can be used for soft tissue repair or augmentation.

Abstract: A power supply unit arrangement for an electronic device includes a first switching converter with a first control loop that provides a controlled output voltage (DC-out) at a node; a second switching converter with a second control loop that alternatively provides the controlled output voltage (DC-out) at the node; and an open-loop control circuit connected to the first control loop and the second control loop, wherein the open-loop control circuit, upon a changeover of the current supply from the first switching converter to the second switching converter, sets a predetermined control state of the first control loop and deactivates the first switching converter and, upon a changeover of the current supply from the second switching converter to the first switching converter, reactivates the first switching converter using the predetermined control state.

Abstract: A method for manufacturing microelectromechanical structures in a layer sequence and a corresponding electronic component having a microelectromechanical structure. The method includes provision of a carrier substrate including a first surface, an application of an insulation layer onto the first surface, an epitaxial growth of a first silicon layer onto the insulation layer, a structuring of the first silicon layer for forming trenches in the first silicon layer, a passivation of the first silicon layer, whereby the trenches are filled and a passivation layer is formed on a side facing away from the first surface, a structuring of the passivation layer, sacrificial areas and functional areas being formed in the first silicon layer, and the sacrificial areas are free of the passivation layer, at least at some points, on a side facing away from the carrier substrate, and, finally, removal of the sacrificial areas.

Abstract: An intervertebral implant includes an insertion end, an opposing engagement end, and first and second opposed main surfaces configured to contact respective adjacent vertebral endplates. Each of the first and second main surfaces has an anterior edge, a posterior edge, and extends between the insertion and engagement ends. Anterior and posterior walls are formed between the first and second main surfaces and along the respective anterior and posterior edges and converge at the insertion and engagement ends. A slot is formed at the engagement end and extends continuously between and at least partially along the anterior and posterior walls. A post is positioned within the slot, spaced from at least one of the anterior and posterior walls and extending at least partially between the first and second main surfaces. The post includes a plurality of exposed facets and is configured for engagement with a pivotable insertion instrument.

Abstract: A series of tricyclic benzimidazole derivatives, in particular dihydro-1H-imidazo [1,2-a]benzimidazole, dihydro-1H-pyrrolo [1,2-a]benzimidazole, dihydro-1H-pyrazino[1,2-a]benzimidazole, dihydro-1H-[1,4]oxazino[4,3-a]benzimidazole and dihydrothiazolo[3,4-a]benzimidazolem, and analogs thereof, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.

Abstract: Embodiments provide systems and methods for activating applications in a distributed asynchronous system based on detecting touches on a display. The system detects an input on a display. The input on the display may be, for example, from a human touch or a pointing device. An input state manager executes hit-testing on a visual tree to identify a selected view using the input on the display. The selected view is compared to an active view. A shell in the system is notified when the selected view does not match the active view. The input state manager is then notified if the selected view should be made a new active view. The system instructs an application activation service to activate an application associated with the selected view. An input state manager is notified when the application associated with the selected view has been made an active view.

Abstract: A method and system for providing ultrasound treatment to a tissue that contains a lower part of dermis and proximal protrusions of fat lobuli into the dermis. An embodiment delivers ultrasound energy to the region creating a thermal injury and coagulating the proximal protrusions of fat lobuli, thereby eliminating the fat protrusions into the dermis. An embodiment can also include ultrasound imaging configurations using the same or a separate probe before, after or during the treatment. In addition various therapeutic levels of ultrasound can be used to increase the speed at which fat metabolizes. Additionally the mechanical action of ultrasound physically breaks fat cell clusters and stretches the fibrous bonds. Mechanical action will also enhance lymphatic drainage, stimulating the evacuation of fat decay products.

Abstract: Disclosed herein are methods of forming one or more transducer elements in a transducer region of a slider by electrodepositing one or more metal ions from an ionic liquid solvent, and related sliders.

Abstract: The invention relates to a suction nozzle and to a blow-out unit for a fan as well as to the fan with a suction nozzle and a blow-out unit.

Abstract: A 4-phenylbutyric acid derivative of Formula (1), wherein Y is selected from 0 or H2; R1 is selected from N2 or H; R2 is a radical of an amino acid, a salicylic acid, a 4-phenylbutyric acid, a catechol, or a derivative of any of the aforementioned; and n is selected from 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10, for use in the treatment of an inflammatory disease, an angiopathic disease, otosclerosis, a mental disorder, or tinnitus.

Abstract: Provided is a self-fitting and automatically adjustable footwear wherein the shoe upper and/or shoe tongue have or are attached to a shape memory material (“SMM”). Upon stimulation, the SMM deforms and brings the footwear to self-assemble about a foot, which further brings two clasp members close to each other and facilitates the clasp thereof to form a self-assembled and closed footwear. The clasp members may be integrated with straps or shoelaces, and optionally SMM. The footwear may include a motor, a control unit, and sensors which enable a motor-actuated fine tensioning of the footwear. A push button to enable manual opening of the footwear may be affixed on the footwear or removably attached to multiple surfaces/locations. The entire assembly generates data transmittable to health care providers and other data trackers. The footwear may include a battery, which may be charged by placing the footwear on a charge dock station.

Abstract: Vehicles including a plurality of front and rear ground engaging members, a front driveline operatively coupled to a first power source, a rear driveline operatively coupled to a second power source, at least one controller operatively coupled to the first drive system and the second drive system are disclosed. The vehicles may further include a torque request input adapted to be actuatable by an operator of the vehicle. The torque request input may provide an indication of a requested torque to the at least one controller. The at least one controller may, based on the requested torque, command a first output of the first drive system to the at least one front ground engaging member and a second output of the second drive system to the at least one rear ground engaging member. Vehicle drive control systems are also disclosed. Methods of controlling torque and battery management are also disclosed.

Abstract: The present invention relates to bispecific polypeptides that are directed against the cellular receptor CD4 as well as a cellular co-receptor for HIV. Said polypeptides may be used to prevent human cell entry of HIV.

Abstract: In one aspect, methods of sensing are described herein. In some embodiments, a method of sensing comprises disposing a fluorophore in a biological environment, wherein the fluorophore comprises a dioxo-pyridine ring (DPR) or a thiazolopyridine acid (TPA). The method further comprises exposing the biological environment to electromagnetic radiation having a wavelength corresponding to an excitation wavelength of the fluorophore, detecting light emitted by the fluorophore, and correlating the light emitted by the fluorophore to a presence or absence of an analyte within the biological environment in an amount above a minimum detection threshold. The presence of the analyte can increase or decrease the amount of light emitted by the fluorophore. The presence of the analyte may also shift the peak emission wavelength or alter the fluorescence lifetime of the fluorophore. The analyte, in some embodiments, comprises hydrogen ions, halide ions, and/or halogens.

Abstract: A method of forming low-energy x-ray absorbers. Sensors may be formed on a semiconductor, e.g., silicon, wafer. A seed metal layer, e.g., gold, is deposited on the wafer and patterned into stem pads for electroplating. Stems, e.g., gold, are electroplated from the stem seed pads through a stem mask. An absorber layer, e.g., gold, is deposited on the wafer, preferably e-beam evaporated. After patterning the absorbers, absorber and stem mask material is removed, e.g., in a solvent bath and critical point drying.

Abstract: A system, method, and apparatus for charging primary battery-powered devices and battery-powered accessories tethered to the primary devices are disclosed. The two devices may include batteries of different types having different nominal voltages. A processing unit on the primary device may obtain state-of-charge information and other operating parameters of the batteries and may determine when to provide power to the accessory to charge its battery. The primary device may select its own battery, power provided by a charger to which it is coupled, or conditioned power as the source of charging energy provided to the accessory to charge its battery. Processing units on the two devices may adjust charging parameters to perform energy balancing while the batteries are simultaneously charged, based on operating parameters of the batteries, operating contexts of the devices, a charging prioritization scheme, or a current distribution scheme.

Abstract: Methods, systems, and devices for wireless communication are described. A base station may allocate resources for communication with a user equipment (UE). The resources may include one or more subframes, and each subframe may include one or more shortened transmission time intervals (sTTIs). Each sTTI may be assigned a transmission direction according to a time division duplex (TDD) pattern. Based on traffic needs and/or interference from other UEs and/or base stations, the base station may determine to modify the TDD pattern used for communication. Accordingly, a base station may transmit an indicator in a control message or control region of a TTI or sTTI, to indicate to users that a transmission direction of an sTTI in the TDD pattern is being changed. Subsequently, a user may communicate with the base station according to the reconfigured TDD pattern.

Abstract: In an embodiment, a localization module can provide coordinates of the vehicle relative to the Earth and relative to the drivable surface, both of which are precise enough to allow for self-driving, and further can compensate for a temporary lapse in reliable GPS service by continuing to track the car's position by tracking its movement with inertial sensors (e.g., accelerometers and gyroscopes) and RADAR data. The localization module bases its output on a geolocation relative to the Earth and sensor measurements of the drivable surface and its surroundings to determine where the car is in relation to the Earth and the drivable surface.