Abstract: The present invention provides for a proteomic approach to predicting, diagnosing and staging invasive bladder cancer, and for predicting patient survival and therapeutic efficacy. More specifically, the target being analyzed for reduced expression is FOXA1, and optionally including analysis of increased FOXA2 expression.

Abstract: The present invention involves a seed firmer with a pusher or embedding attachment that extends the life of the seed firmer. The seed firmer has a flexible portion adapted to be coupled to a seed chute of a planter. Also, a firming arm flexibly is connected to the flexible portion, with the firming arm having an engagement portion bounded at one end by a stop. Additionally, an extender attachment is mechanically coupled to the engagement portion and abuts the stop.

Abstract: Active compound combinations are disclosed which comprise (A) a dithiino-tetracarboximide of formula (I) and a further insecticidally active compound (B). Methods for controlling animal pests such as insects and/or unwanted acarids and for curatively or preventively controlling the phytopathogenic fungi of plants or crops are also disclosed as well as the use of a composition according to the invention for the treatment of seed, to a method for protecting a seed and to the treated seed.

Abstract: One embodiment includes a method for creating a recessed pattern in a substrate. The method includes laser ablating the substrate to form a recessed complex edge geometry in the substrate. The recessed complex edge geometry forms at least a portion of the pattern. The method also includes machining a remainder of the pattern with a mechanical cutter.

Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH286440. The invention thus relates to the plants, seeds and tissue cultures of the variety CH286440, and to methods for producing a corn plant produced by crossing a corn plant of variety CH286440 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH286440.

Abstract: A safety device 20 for shielding a medical needle 25 comprises a needle mount 28 supporting a medical needle and a needle shielding sleeve 34 arranged coaxially with the mount for sliding movement from an initial needle shielding position to a non-shielding position whereat at least the tip of the needle is exposed beyond the sleeve. Either the sleeve 34 or the mount 28 has both an abutment surface 31 and a sliding surface 29. A flexible connection mounts a radially deformable resilient finger 37 on the other of the sleeve and mount so that a first finger part 46 is configured for radial alignment with the abutment surface 31 where the finger blocks movement of the sleeve or for radial alignment with the sliding surface. A control member 40 is slidable coaxially with the sleeve and is co-operable with a second finger part 47 to the other side of said flexible connection.

Abstract: Ophthalmic suture materials made from biocompatible and biodegradable polymers with high tensile strength for use in drug delivery, methods of making them, and method of using them for ocular surgery and repair have been developed. The suture materials are made from a combination of a biodegradable, biocompatible polymer and a hydrophilic biocompatible polymer. In a preferred embodiment the suture materials are made from a poly(hydroxyl acid) such as poly(l-lactic acid) and a polyalkylene oxide such as poly(ethylene glycol) or a polyalkylene oxide block copolymer. The sutures entrap (e.g., encapsulate) one or more therapeutic, prophylactic or diagnostic agents and provide prolonged release over a period of at least a week, preferably a month.

Abstract: A method for providing watermark to subscribers is provided. The method comprises observing a request for a first content from a subscriber, determining if the subscriber can receive a watermark, generating a second content comprising the watermark if the subscriber can receive a watermark, causing the subscriber to fetch the first content, and causing the subscriber to fetch the second content comprising the watermark overlaying the first content.

Abstract: The current invention comprises a function library and relates to Artificial Intelligence systems and devices. Within a Dynamic Neural Network (the “Intelligent Target Device”) training model values are autonomously generated in during learning and stored in synaptic registers. One instance of an Intelligent Target Device is the “Autonomous Learning Dynamic Artificial Neural Computing Device and Brain Inspired System”, described in patent application number 20100076916 and referenced in whole in this text. A collection of values that has been generated in synaptic registers comprises a training model, which is an abstract model of a task or a process that has been learned by the intelligent target device. A means is provided within the Intelligent Target Device to copy the training model to computer memory. A collection of such training model sets are stored within a function library on a computer storage facility, such as a disk, CD, DVD or other means.

Abstract: A preassembled line for axial engagement with a mating coupling part. The preassembled line includes a line connector having of a connector body with a connecting portion to which a media line is connected and also includes a coupling portion with sealing means for sealing relative to the mating coupling part. The media line is provided with a heating wire arranged on the coupling portion. The connector body, the media line and the heating wire being surrounded at one end by a housing that has a latching part for connecting with the mating coupling part. The latching part is formed on the housing portion surrounding the coupling portion. Sealing of the preassembled media line to the mating coupling part is separated from connecting of the preassembled media line to the mating coupling part and separately performed by the connector body and the housing.

Abstract: A dose counter for use in connection with a device adapted for metered dispensing of a medication is described. The dose counter has a first count indicator that has a first indicia bearing surface, with the first count indicator being rotatable about a first axis. The dose counter also has a second count indicator that has a second indicia bearing surface, with the second count indicator being rotatable about a second axis. The second axis is disposed at an obtuse angle with respect to the first axis, and the first and second indicia bearing surfaces align at a common viewing area to collectively present at least a portion of a medication dosage count.

Abstract: The application discloses a microplate, wherein the openings of the wells for receiving reagents have a collar, wherein the collar comprises at least two upwardly extending rims, wherein the rims are radially separated by a gap (4), and wherein the rims are circumferentially closed. Furthermore, multiwall strips with such double rimmed wells are disclosed.

Abstract: A sensor chip (100) for use in multiplexed analysis of at least one sample is described. The sensor chip (100) comprises a plurality of sensing sites, each sensing site adapted for sensing an optional interaction of a sample with a component and an input waveguide for receiving radiation from a frequency comb radiation source and guiding said radiation along said plurality of sensing sites. At each sensing site, a distinct optical sensitive element is adapted for, at a distinct frequency, sensing an optional interaction of said sample with said component. An output means provides output of the radiation representative for the sensing dependent on said optional interaction of said sample with said component at said plurality of sensing sites.

Abstract: The present invention relates to compositions for preventing or treating allergy to ragweed by tolerisation. The compositions are based on combinations of peptide fragments derived from the major allergen in ragweed pollen, Amb a 1. The invention also relates to products, vectors and formulations which may be used to provide polypeptides of the invention in combination. The invention further relates to in vitro methods for determining whether T cells recognize a polypeptide of the invention, and for determining whether an individual has or is at risk of a condition characterized by allergic symptoms in response to a ragweed allergen.

Abstract: An oral device includes an intraoral bolus simulator comprising an exterior surface and having an interior volume fillable with a fluid. An extraoral user interface extends from the bolus simulator, and can be used to locate or position the intraoral bolus simulator. In various embodiments, the fluid may be a gas or a liquid, or combinations thereof. In other embodiments, an oral device includes an extraoral handle, a shield connected to the handle, a tether extending from the shield, and a bolus simulator connected to the tether.

Abstract: A laminated glazing comprising: a thick ply of glass having a thickness in the range 1.9 to 2.4 mm; a polymer interlayer; and a thin ply of glass having a thickness in the range 0.8 to 1.4 mm, wherein the relative optical power of the glazing is less than would be predicted from the single glass reflected optical power of the plies before lamination.

Abstract: The present invention relates to a concentrator for focusing solar radiation, having surface structuring in the form of one or more Fresnel lenses on the lower side, and to the production thereof from polymeric materials by means of a specific extrusion process. The inventive concentrator can be employed in plants utilizable for photovoltaic or solar heating purposes, and has the required durability and performance in demanding climatic zones. The inventive concentrator enables particularly economic production and efficient concentration of solar radiation onto objects such as solar cells or absorber units, irrespective of the geometry thereof. The inventive concentrator has high longevity and—combined with this—high optical performance when employed in extreme and demanding climatic zones.

Abstract: Systems and methods described herein relate to detecting the existence of unauthorized content in multiuser composite media stream. In particular, multiuser composite media streams can be examined and to determine if these composite streams include unauthorized content such as copyrighted content or nudity, violence, language violations where desired. The multiuser composite media stream can be partitioned into sections associated with broadcasting users and the portions can be analyzed independently. A notification can be provided to, e.g., the broadcasting user responsible for the unauthorized content in response to detection of the unauthorized content.

Abstract: A fluid ejection device includes a firing chamber having an ejection orifice opposite a chamber floor, a heating element and a mesa projecting from the chamber floor, the mesa is spaced from the heating element to define a passive zone between the mesa and heating element.

Abstract: The present invention provides TCRs having high affinity. The TCR binds to SLYNTVATL (SEQ ID NO:16)-HLA-A*0201 with a KD of less than or equal to 1 ?M and/or an off-rate (koff) of 1×10?3 S?1 or slower using Surface Plasmon Resonance. The TCRs are non-native, isolated or recombinant. The TCRs are useful, either alone, or with a therapeutic agent, for targeting HIV infected cells that present the SLYNTVATL (SEQ ID NO:16)-HLA-A*0201 complex.