Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: A vehicle is provided that includes a sensor arrangement configured to sense one or more regions proximate to an exterior of the vehicle, and a controller configured to process signals generated by the sensor arrangement and to detect and generate a geometric profile of a trailer in the one or more regions proximate to the exterior of the vehicle, the controller further determining an air resistance of the trailer based on the geometric profile and calculating an expected driving range of the vehicle based on the detected air resistance.

Abstract: Herein described is a portable sanitation apparatus for pet waste disposal and method for using the same comprising a micro-composite structure and a means for securing micro-composite structures together to form a macro-composite structure in variable geometric Configurations and sizes for greater area coverage.

Abstract: Herein described is a portable sanitation apparatus for pet waste disposal and method for using the same comprising a micro-composite structure and a means for securing micro-composite structures together to form a macro-composite structure in variable geometric configurations and sizes for greater area coverage. Also described is a vertical member for substantially containing pet waste within the floor area covered by the composite structure.

Abstract: Herein described is a portable sanitation apparatus for pet waste disposal and method for using the same comprising a micro-composite structure and a means for securing micro-composite structures together to form a macro-composite structure in variable geometric configurations and sizes for greater area coverage. Also described is a vertical member for substantially containing pet waste within the floor area covered by the composite structure.

Abstract: Printed circuit board apparatus with electromagnetic interference shields and methods of making the same.

Abstract: Herein described is a portable sanitation apparatus for pet waste disposal and method for using the same comprising an overall composite structure with a plurality of primary layers with one or more sublayers and an engagement means for attaching the two primary layers together.

Abstract: Printed circuit board apparatus with electromagnetic interference shields and methods of making the same.

Abstract: Herein described is a portable sanitation apparatus for pet waste disposal and method for using the same comprising a micro-composite structure and a means for securing micro-composite structures together to form a macro-composite structure in variable geometric Configurations and sizes for greater area coverage.

Abstract: The present invention relates to a handle for use with an item of luggage. The handle comprises an outer shell, at least one inner bar and at least one strain gauge, wherein the at least one inner bar extends out from within the outer shell at each end of the handle such that the item of luggage may be attached to the handle using the at least one inner bar. The arrangement is such that when an item of luggage is lifted using the handle, the weight of the suitcase is measured using the at least one strain gauge.

Abstract: A reconstitution device for storing a first component of a pharmaceutical preparation includes a receptacle, a cap having a first end secured to the receptacle, a second end, and an inner bore having a central aperture. The device further includes a stopper located between the receptacle and the cap, the stopper including a portion capable of being perforated. The device also includes a plunger secured to the second end of the cap, a locking mechanism located in the cap, and an actuating mechanism. The actuating mechanism may prevent the device from inadvertent activation.

Abstract: This invention concerns compositions of tipifarnib, mannitol, and hydroxypropyl-?-cyclodextrin and, suitable for intravenous (IV) administration. The invention further concerns the use of such formulation and processes for preparing such formulations and methods of treating by administering said formulations.

Abstract: Brace for Carrying Papers/Books on Arm is a holder for mail, papers, magazines, books or the like. The preferred embodiment of the invention utilizes a brace, a backing, a ledge and a cut-out to allow a user to cradle the mail, papers, magazines, books or the like. To use the preferred embodiment of Brace for Carrying Papers/Books on Arm, an individual would rest the backing on their forearm while resting the ledge against the front of their body and their wrist in the cut-out. The user would then place the appropriate objects such as papers, mail, books or other items on the backing against the brace and the ledge.

Abstract: Methods of treating ground water and methods for reducing contaminants (e.g., chlorinated compounds in contaminated ground water) to harmless compounds in the presence of an elemental metal treatment composition. Said methods comprise injecting a treatment solution comprising a colloidal suspension of elemental metal particles (e.g., iron, a tin, a zinc, a palladium and mixtures thereof) having a nanoscale particle size and a carbohydrate in an organic liquid (e.g., dodecane, butyl acetate and polypropylene glycol ethyl ether acetate and mixtures thereof) into the ground, proximate to the contaminated ground water.

Abstract: This document discusses, among other things, systems and methods for generating data in a standardized machine-readable format. A method receives data from one or more patient health monitors at a centralized repository. The method then generates one or more files containing at least a portion of the data and stores the files in a secured web folder. The method then permits access to the files based on one or more security schemes.

Abstract: This document discusses, among other things, systems and methods for generating data in a standardized machine-readable format. A method monitors a secured area in a centralized repository; detects the creation of one or more files at the centralized repository, wherein the files include patient-related data, and in response to detecting the creation: connects to the centralized repository from a computer associated with a medical practice; authenticates the connection to access a secured area; and accesses one or more files in the secured area.

Abstract: A fuel system for use in an internal combustion engine includes a plurality of fuel injectors, each injector including at least one capillary flow passage, the at least one capillary flow passage having an inlet end and an outlet end, a heat source arranged along the at least one capillary flow passage, the heat source operable to heat a liquid fuel in the at least one capillary flow passage to a level sufficient to convert at least a portion thereof from the liquid state to a vapor state, and a valve for metering fuel to the internal combustion engine, a controller to control the power supplied to the heat source of each of the plurality of fuel injectors to achieve a predetermined target temperature, a sensor for use in determining engine air flow and a sensor for measuring a value indicative of degree of engine warm-up of the internal combustion engine.

Abstract: A method for controlling a fuel system of an internal combustion engine. The method is employed with a fuel system having a source of alcohol-containing liquid fuel, at least one fuel injector, a heat source for heating the liquid fuel in the at least one fuel injector, the heat source capable of heating the liquid fuel to a level sufficient to convert at least a portion thereof from the liquid state to a vapor state and a metering valve operable to achieve a range of flow rates characterized by a valve open versus valve closed duty cycle. The method includes the steps of metering a predetermined amount of fuel based on engine operating conditions, controlling power supplied to the heat source of the at least one fuel injector to achieve a target temperature, determining alcohol concentration of the fuel and adjusting the power supplied to the heat source of the at least one fuel injector based on the alcohol concentration determination.

Abstract: This invention concerns novel formulations of tipifarnib, which is suitable for intravenous (IV) administration. The invention further concerns the use of such formulation and processes for preparing such formulations and methods of treating by administering said formulations.

Abstract: A fuel injector for vaporizing a liquid fuel for use in an internal combustion engine. The fuel injector includes at least one capillary flow passage, a heat source arranged along the at least one capillary flow passage, the heat source operable to heat the liquid fuel in the at least one capillary flow passage to a level sufficient to change at least a portion thereof from the liquid state to a vapor state and deliver a stream of substantially vaporized fuel from the outlet end of the at least one capillary flow passage; and a valve for metering fuel to the internal combustion engine, the valve located proximate to the outlet end of the at least one capillary flow passage, the valve including a low mass member for substantially occluding the stream of fuel to the internal combustion engine; wherein the low mass member for substantially occluding the stream of fuel to the internal combustion engine is formed of a material having low mass and or a low coefficient of thermal conductivity.