Patents by Inventor Peter Parham

Peter Parham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and reagents for typing HLA class I genes
    Patent number: 6103465
    Abstract: A method for typing HLA class 1 genes. The method entails first contacting a sample DNA with first and second amplification primers, wherein the first and second primers are each at least partially located in an exonic region. Next, using the first and second primers, a target sequence is amplified by the PCR to form an amplicon of the target sequence. Finally, the amplicon is detected with a sequence-specific detection means, e.g., DNA sequencing. The invention also includes specific amplification primers, specific sequencing primers, and kits especially adapted for use with the above HLA typing method.
    Type: Grant
    Filed: October 3, 1995
    Date of Patent: August 15, 2000
    Assignee: The Perkin-Elmer Corporation
    Inventors: Leslie Johnston-Dow, Robert B. Chadwick, Peter Parham
  • Cytotoxic T-cell lymphocyte ("CTL") activity regulation by class I MHC peptides
    Patent number: 5723128
    Abstract: Fragments from the polymorphic domains of Class I HLA antigen domains are used to modulate T-cell activity. The peptides are from the .alpha.1- or .alpha.2 domains, particularly of the HLA-A, and B antigens. The peptides may be conjugated to other compounds to be used in diagnosis and therapy. The peptides may block lysis, CTL proliferation or have other regulating effects.
    Type: Grant
    Filed: April 5, 1994
    Date of Patent: March 3, 1998
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Carol Clayberger, Alan M. Krensky, Peter Parham