Patents by Inventor Peter Qiang Qu
Peter Qiang Qu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240035067Abstract: An integrated sample purification system includes a housing, a sample container rack, a filter holder, and a cylindrical magnet. The sample container rack and the filter device holder are disposed in the housing. The sample container rack is configured to hold one or more sample containers, the filter device holder is configured to hold one or more filter devices. The cylindrical magnet is adjacent to and external to the sample container rack, and is rotated about a central, longitudinal axis of the magnet by an electric motor disposed in the housing to lyse cells. Molecules of interest in the lysed cells are purified using filters that bind specifically to the molecules of interest. The system is readily amenable to automation and rapid purification and analysis of molecules of interest, such as nucleic acids and proteins.Type: ApplicationFiled: July 10, 2023Publication date: February 1, 2024Inventors: Christopher G. COONEY, Rebecca HOLMBERG, Phillip BELGRADER, Peter Qiang QU
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Publication number: 20230349897Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: ApplicationFiled: July 10, 2023Publication date: November 2, 2023Inventors: Christopher G. COONEY, Peter Qiang QU, Alexander PEROV, Jennifer PARKER
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Patent number: 11767549Abstract: An integrated sample purification system includes a housing, a sample container rack, a filter holder, and a cylindrical magnet. The sample container rack and the filter device holder are disposed in the housing. The sample container rack is configured to hold one or more sample containers, the filter device holder is configured to hold one or more filter devices. The cylindrical magnet is adjacent to and external to the sample container rack, and is rotated about a central, longitudinal axis of the magnet by an electric motor disposed in the housing to lyse cells. Molecules of interest in the lysed cells are purified using filters that bind specifically to the molecules of interest. The system is readily amenable to automation and rapid purification and analysis of molecules of interest, such as nucleic acids and proteins.Type: GrantFiled: December 30, 2020Date of Patent: September 26, 2023Assignee: AKONNI BIOSYSTEMS, INC.Inventors: Christopher G. Cooney, Rebecca Holmberg, Phillip Belgrader, Peter Qiang Qu
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Patent number: 11747332Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: GrantFiled: November 24, 2020Date of Patent: September 5, 2023Assignee: AKONNI BIOSYSTEMS, INC.Inventors: Christopher G. Cooney, Peter Qiang Qu, Alexander Perov, Jennifer Parker
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Publication number: 20220062909Abstract: A molecular testing device comprises a heating and cooling module having a thin-film thermoelectric heating and cooling device, and a removable test module having a combined amplification and hybridization reaction chamber. The reaction chamber comprises a thermo-conductive exterior surface and a microarray on an interior surface. The thin-film thermoelectric heating and cooling device has a heat transfer surface that is adapted to make contact with the thermo-conductive exterior surface of the reaction chamber. The molecular testing device may be used to perform a PCR in the reaction chamber.Type: ApplicationFiled: August 5, 2021Publication date: March 3, 2022Inventors: Christopher G. COONEY, Peter Qiang QU, Arial BUENO
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Patent number: 11097278Abstract: A molecular testing device comprises a heating and cooling module having a thin-film thermoelectric heating and cooling device, and a removable test module having a combined amplification and hybridization reaction chamber. The reaction chamber comprises a thermo-conductive exterior surface and a microarray on an interior surface. The thin-film thermoelectric heating and cooling device has a heat transfer surface that is adapted to make contact with the thermo-conductive exterior surface of the reaction chamber. The molecular testing device may be used to perform a PCR in the reaction chamber.Type: GrantFiled: September 24, 2018Date of Patent: August 24, 2021Assignee: AKONNI BIOSYSTEMS, INC.Inventors: Christopher G. Cooney, Peter Qiang Qu, Arial Bueno
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Publication number: 20210230668Abstract: An integrated sample purification system includes a housing, a sample container rack, a filter holder, and a cylindrical magnet. The sample container rack and the filter device holder are disposed in the housing. The sample container rack is configured to hold one or more sample containers, the filter device holder is configured to hold one or more filter devices. The cylindrical magnet is adjacent to and external to the sample container rack, and is rotated about a central, longitudinal axis of the magnet by an electric motor disposed in the housing to lyse cells. Molecules of interest in the lysed cells are purified using filters that bind specifically to the molecules of interest. The system is readily amenable to automation and rapid purification and analysis of molecules of interest, such as nucleic acids and proteins.Type: ApplicationFiled: December 30, 2020Publication date: July 29, 2021Inventors: Christopher G. COONEY, Rebecca HOLMBERG, Phillip BELGRADER, Peter Qiang QU
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Publication number: 20210215689Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: ApplicationFiled: November 24, 2020Publication date: July 15, 2021Inventors: Christopher G. COONEY, Peter Qiang QU, Alexander PEROV, Jennifer PARKER
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Patent number: 10882046Abstract: A molecular testing device comprises a heating and cooling module having a thin-film thermoelectric heating and cooling device, and a removable test module having a combined amplification and hybridization reaction chamber. The reaction chamber comprises a thermo-conductive exterior surface and a microarray on an interior surface. The thin-film thermoelectric heating and cooling device has a heat transfer surface that is adapted to make contact with the thermo-conductive exterior surface of the reaction chamber. The molecular testing device may be used to perform a PCR in the reaction chamber.Type: GrantFiled: August 21, 2018Date of Patent: January 5, 2021Assignee: AKONNI BIOSYSTEMS, INC.Inventors: Christopher G. Cooney, Peter Qiang Qu, Arial Bueno
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Patent number: 10877028Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: GrantFiled: September 13, 2019Date of Patent: December 29, 2020Assignee: Akonni Biosystems, Inc.Inventors: Christopher G. Cooney, Peter Qiang Qu, Alexander Perov, Jennifer Parker
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Publication number: 20200188908Abstract: An integrated sample analysis system is disclosed. The sample analysis system contains (1) a sample preparation/analysis module having sample purification device comprising a monolith that binds specifically to nucleic acids and a sample analysis device comprising a microarray enclosed in a reaction chamber having a hydrophilic interior surface; (2) a temperature control module comprising a thermocycler having a thermally conductive temperature-control bladder; and (3) an imaging device capable of capturing an image of the microarray in the reaction chamber.Type: ApplicationFiled: December 9, 2019Publication date: June 18, 2020Inventors: Christopher G. COONEY, Phillip Belgrader, Arial Bueno, Steve Garber, Nitu Harshendu Thakore, Peter Qiang Qu
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Patent number: 10547736Abstract: A system and method for determining a presence of a mobile device located in a predetermined detection zone within a vehicle may include a plurality of transmitters located within the vehicle, in which each of the plurality of transmitters is configured to transmit an acoustic signal into an acoustic environment within the vehicle, and in which each of the acoustic signals comprises at least one ultrasonic pulse, a mobile device configured to periodically record sounds in the acoustic environment, and a processor configured to determine that a periodically recorded sound by the mobile device comprises each of the acoustic signals transmitted by the plurality of transmitters, determine a location of the mobile device within the vehicle based on the acoustic signals recorded by the mobile device, and determine that the location of the mobile device matches the predetermined detection zone.Type: GrantFiled: December 19, 2018Date of Patent: January 28, 2020Assignee: Driving Management Systems, Inc.Inventors: Marwan Hannon, Peter Qiang Qu, James W. Allison, Cristian Cesane
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Patent number: 10532352Abstract: An integrated sample analysis system is disclosed. The sample analysis system contains (1) a sample preparation/analysis module having sample purification device comprising a monolith that binds specifically to nucleic acids and a sample analysis device comprising a microarray enclosed in a reaction chamber having a hydrophilic interior surface; (2) a temperature control module comprising a thermocycler having a thermally conductive temperature-control bladder; and (3) an imaging device capable of capturing an image of the microarray in the reaction chamber.Type: GrantFiled: April 3, 2019Date of Patent: January 14, 2020Assignee: Akonni Biosystems, Inc.Inventors: Christopher G. Cooney, Phillip Belgrader, Arial Bueno, Steve Garber, Nitu Harshendu Thakore, Peter Qiang Qu
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Patent number: 10526645Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: GrantFiled: September 29, 2016Date of Patent: January 7, 2020Inventors: Christopher G. Cooney, Peter Qiang Qu, Alexander Perov, Jennifer Parker
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Publication number: 20200002755Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: ApplicationFiled: September 13, 2019Publication date: January 2, 2020Inventors: Christopher G. Cooney, Peter Qiang QU, Alexander PEROV, Jennifer PARKER
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Publication number: 20190224668Abstract: An integrated sample analysis system is disclosed. The sample analysis system contains (1) a sample preparation/analysis module having sample purification device comprising a monolith that binds specifically to nucleic acids and a sample analysis device comprising a microarray enclosed in a reaction chamber having a hydrophilic interior surface; (2) a temperature control module comprising a thermocycler having a thermally conductive temperature-control bladder; and (3) an imaging device capable of capturing an image of the microarray in the reaction chamber.Type: ApplicationFiled: April 3, 2019Publication date: July 25, 2019Inventors: Christopher G. COONEY, Phillip Belgrader, Arial Bueno, Steve Garber, Nitu Harshendu Thakore, Peter Qiang Qu
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Publication number: 20190199850Abstract: A system and method for determining a presence of a mobile device located in a predetermined detection zone within a vehicle may include a plurality of transmitters located within the vehicle, in which each of the plurality of transmitters is configured to transmit an acoustic signal into an acoustic environment within the vehicle, and in which each of the acoustic signals comprises at least one ultrasonic pulse, a mobile device configured to periodically record sounds in the acoustic environment, and a processor configured to determine that a periodically recorded sound by the mobile device comprises each of the acoustic signals transmitted by the plurality of transmitters, determine a location of the mobile device within the vehicle based on the acoustic signals recorded by the mobile device, and determine that the location of the mobile device matches the predetermined detection zone.Type: ApplicationFiled: December 19, 2018Publication date: June 27, 2019Inventors: Marwan Hannon, Peter Qiang Qu, James W. Allison, Cristian Cesane
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Patent number: 10300482Abstract: An integrated sample analysis system is disclosed. The sample analysis system contains (1) a sample preparation/analysis module having sample purification device comprising a monolith that binds specifically to nucleic acids and a sample analysis device comprising a microarray enclosed in a reaction chamber having a hydrophilic interior surface; (2) a temperature control module comprising a thermocycler having a thermally conductive temperature-control bladder; and (3) an imaging device capable of capturing an image of the microarray in the reaction chamber.Type: GrantFiled: December 8, 2011Date of Patent: May 28, 2019Assignee: AKONNI BIOSYSTEMS, INC.Inventors: Christopher G. Cooney, Phillip Belgrader, Arial Bueno, Steve Garber, Nitu Harshendu Thakore, Peter Qiang Qu
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Publication number: 20190078138Abstract: An integrated sample purification system includes a housing, a sample container rack, a filter holder, and a cylindrical magnet. The sample container rack and the filter device holder are disposed in the housing. The sample container rack is configured to hold one or more sample containers, the filter device holder is configured to hold one or more filter devices. The cylindrical magnet is adjacent to and external to the sample container rack, and is rotated about a central, longitudinal axis of the magnet by an electric motor disposed in the housing to lyse cells, Molecules of interest in the lysed cells are purified using filters that bind specifically to the molecules of interest. The system is readily amenable to automation and rapid purification and. analysis of molecules of interest, such as nucleic acids and proteins.Type: ApplicationFiled: October 11, 2018Publication date: March 14, 2019Inventors: Christopher G. COONEY, Rebecca HOLMBERG, Phillip BELGRADER, Peter Qiang QU
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Patent number: 10205819Abstract: A system and method for determining a presence of a mobile device located in a predetermined detection zone within a vehicle may include a plurality of transmitters located within the vehicle, in which each of the plurality of transmitters is configured to transmit an acoustic signal into an acoustic environment within the vehicle, and in which each of the acoustic signals comprises at least one ultrasonic pulse, a mobile device configured to periodically record sounds in the acoustic environment, and a processor configured to determine that a periodically recorded sound by the mobile device comprises each of the acoustic signals transmitted by the plurality of transmitters, determine a location of the mobile device within the vehicle based on the acoustic signals recorded by the mobile device, and determine that the location of the mobile device matches the predetermined detection zone.Type: GrantFiled: July 14, 2016Date of Patent: February 12, 2019Assignee: DRIVING MANAGEMENT SYSTEMS, INC.Inventors: Marwan Hannon, Peter Qiang Qu, James W. Allison, Cristian Cesane