Patents by Inventor Peter R Baum

Peter R Baum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BTL-II proteins
    Patent number: 7244822
    Abstract: The invention provides isolated BTL-II proteins, nucleic acids, antibodies, antagonists, and agonists and methods of making and using the same. Diagnostic, screening, and therapeutic methods using the compositions of the invention are provided. For example, the compositions of the invention can be used for diagnosis and treatment of inflammatory bowel diseases and for enhancing a mucosal immune response to an antigen.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: July 17, 2007
    Assignee: Immunex Corporation
    Inventors: Peter R. Baum, Sabine S. Escobar, Joanne L. Viney
  • Nectin polypeptides
    Patent number: 7175849
    Abstract: This invention relates to nectin polypeptides and polynucleotides, to methods of making such polypeptides and polynucleotides, and to methods of using such polypeptides and polynucleotides to modulate cell adhesion, cell migration, and angiogenesis, to treat conditions related to cell adhesion including endothelial and epithelial cell proliferation, migration, and barrier function, and to identify agents that alter nectin polypeptide activities.
    Type: Grant
    Filed: October 5, 2001
    Date of Patent: February 13, 2007
    Assignee: Immunex Corporation
    Inventors: Peter R Baum, William C Fanslow, III, Timothy E Lofton, Eric A Sorensen, Adel Youakim
  • BTL-II nucleic acids, proteins, and antibodies
    Publication number: 20040209289
    Abstract: The invention provides isolated BTL-II proteins, nucleic acids, antibodies, antagonists, and agonists and methods of making and using the same. Diagnostic, screening, and therapeutic methods using the compositions of the invention are provided. For example, the compositions of the invention can be used for diagnosis and treatment of inflammatory bowel diseases and for enhancing a mucosal immune response to an antigen.
    Type: Application
    Filed: December 19, 2003
    Publication date: October 21, 2004
    Inventors: Peter R. Baum, Sabine S. Escobar, Joanne L. Viney
  • Novel cytokine designated elk ligand
    Publication number: 20040022767
    Abstract: elk ligand (elk-L) polypeptides as well as DNA sequences, vectors and transformed host cells useful in providing elk-L polypeptides. The elk-L polypeptide binds to a cell surface receptor that is a member of the tyrosine kinase receptor family.
    Type: Application
    Filed: January 31, 2003
    Publication date: February 5, 2004
    Inventors: Stewart D. Lyman, M. Patricia Beckmann, Peter R. Baum, Melissa K. Carpenter
  • Human B7 polypeptides
    Publication number: 20030180309
    Abstract: This invention relates to B7-H1.2 and Butryophilin 2/3, new members of the human B7 polypeptide family, methods of making such polypeptides, and to methods of using them to treat immunological conditions and to identify compounds that alter the activities of these human B7 polypeptides.
    Type: Application
    Filed: January 7, 2002
    Publication date: September 25, 2003
    Inventors: Peter R. Baum, Robert F. DuBose, Steven R. Wiley
  • Molecules designated B7L-1
    Publication number: 20030144478
    Abstract: The invention is directed to B7L-1 as a purified and isolated protein, the DNA encoding the B7L-1, host cells transfected with cDNAs encoding B7L-1 and processes for preparing B7L-1 polypeptides.
    Type: Application
    Filed: November 21, 2002
    Publication date: July 31, 2003
    Applicant: Immunex Corporation
    Inventor: Peter R. Baum
  • Human and murine cytokine polypeptides
    Publication number: 20030134306
    Abstract: This invention relates to IMX7189 cytokines and to new members of the human cytokine polypeptide family, methods of making such polypeptides, and to methods of using them to treat conditions and diseases involving proliferation and/or differentiation of cells from pluripotent stem cell precursors, and to identify compounds that alter cytokine polypeptide activities.
    Type: Application
    Filed: October 2, 2002
    Publication date: July 17, 2003
    Inventors: Peter R. Baum, Bruce A. Mosley, Randal R. Ketchem
  • Cytokine polypeptides
    Publication number: 20030104579
    Abstract: This invention relates to IMX129840 cytokines, including new mammalian cytokine polypeptides; to methods of making such polypeptides; to methods of using them to treat conditions and diseases involving proliferation and/or differentiation of cells from pluripotent stem cell precursors; and to methods of identifying compounds that alter IMX129840 cytokine polypeptide activities.
    Type: Application
    Filed: May 8, 2002
    Publication date: June 5, 2003
    Inventors: Peter R. Baum, Bruce A. Mosley, Randal R. Ketchem, Scott L. Taylor
  • Methods for using elk-L to enhance neuronal survival
    Patent number: 6540992
    Abstract: Elk ligand (Elk-L) polypeptides as well as DNA sequences, vectors and transformed host cells useful in providing elk-L polypeptides are used in methods for enhancing the survival or inhibiting the death of neurons, particularly hippocampal neurons. The elk-L polypeptides bind to a cell surface receptor that is a member of the tyrosine kinase receptor family.
    Type: Grant
    Filed: March 16, 1998
    Date of Patent: April 1, 2003
    Assignee: Genentech, Inc.
    Inventors: Stewart Lyman, M. Patricia Beckmann, Peter R. Baum, Melissa K. Carpenter
  • Nectin polypeptides, polynucleotides, methods of making and use thereof
    Publication number: 20030044893
    Abstract: This invention relates to nectin polypeptides and polynucleotides, to methods of making such polypeptides and polynucleotides, and to methods of using such polypeptides and polynucleotides to modulate cell adhesion, cell migration, and angiogenesis, to treat conditions related to cell adhesion including endothelial and epithelial cell proliferation, migration, and barrier function, and to identify agents that alter nectin polypeptide activities.
    Type: Application
    Filed: October 5, 2001
    Publication date: March 6, 2003
    Inventors: Peter R. Baum, William C. Fanslow, Timothy E. Lofton, Eric A. Sorensen, Adel Youakim
  • Molecules designated B7L-1
    Patent number: 6512095
    Abstract: The invention is directed to B7L-1 as a purified and isolated protein, the DNA encoding the B7L-1, host cells transfected with cDNAs encoding B7L-1 and processes for preparing B7L-1 polypeptides.
    Type: Grant
    Filed: February 6, 2001
    Date of Patent: January 28, 2003
    Assignee: Immunex Corp.
    Inventor: Peter R. Baum
  • Molecules designated B7L-1
    Publication number: 20020164686
    Abstract: The invention is directed to B7L-1 as a purified and isolated protein, the DNA encoding the B7L-1, host cells transfected with cDNAs encoding B7L-1 and processes for preparing B7L-1 polypeptides.
    Type: Application
    Filed: February 6, 2001
    Publication date: November 7, 2002
    Inventor: Peter R. Baum
  • Cytokine which is a ligand for OX40
    Patent number: 5783665
    Abstract: There is disclosed a polypeptide (OX40-L) and DNA sequences, vectors and transformed host cells useful in providing OX40-L polypeptides. More particularly, this invention provides isolated murine OX40-L polypeptides that bind to the extracellular binding region of OX40.
    Type: Grant
    Filed: June 22, 1995
    Date of Patent: July 21, 1998
    Assignee: Immunex Corporation
    Inventors: Peter R. Baum, William C. Fanslow, III, Richard B. Gayle, Raymond G. Goodwin
  • Antibodies directed against elk ligand
    Patent number: 5728813
    Abstract: Antibodies to elk ligand (elk-L) polypeptides as well as DNA sequences, vectors and transformed host cells useful in providing elk-L polypeptides. The elk-L polypeptide binds to a cell surface receptor that is a member of the tyrosine kinase receptor family.
    Type: Grant
    Filed: November 12, 1996
    Date of Patent: March 17, 1998
    Assignee: Immunex Corporation
    Inventors: Stewart Lyman, M. Patricia Beckmann, Peter R. Baum
  • Elk ligand fusion proteins
    Patent number: 5670625
    Abstract: elk ligand (elk-L) polypeptides as well as DNA sequences, vectors and transformed host cells useful in providing elk-L polypeptides. The elk-L polypeptide binds to a cell surface receptor that is a member of the tyrosine kinase receptor family.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: September 23, 1997
    Assignee: Immunex Corporation
    Inventors: Stewart Lyman, M. Patricia Beckmann, Peter R. Baum
  • Cytokine designated elk ligand
    Patent number: 5627267
    Abstract: elk ligand (elk-L) polypeptides as well as DNA sequences, vectors and transformed host cells useful in providing elk-L polypeptides. The elk-L polypeptide binds to a cell surface receptor that is a member of the tyrosine kinase receptor family.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: May 6, 1997
    Assignee: Immunex Corporation
    Inventors: Stewart Lyman, M. Patricia Beckmann, Peter R. Baum
  • Cytokine designated elk ligand
    Patent number: 5512457
    Abstract: elk ligand (elk-L) polypeptides as well as DNA sequences, vectors and transformed host cells useful in providing elk-L polypeptides. The elk-L polypeptide binds to a cell surface receptor that is a member of the tyrosine kinase receptor family.
    Type: Grant
    Filed: March 15, 1994
    Date of Patent: April 30, 1996
    Assignee: Immunex Corporation
    Inventors: Stewart Lyman, M. Patricia Beckmann, Peter R. Baum, Melissa K. Carpenter
  • Cytokine which is a ligand for OX40
    Patent number: 5457035
    Abstract: There is disclosed a polypeptide (OX40-L) and DNA sequences, vectors and transformed host cells useful in providing OX40-L polypeptides. More particularly, this invention provides isolated murine OX40-L polypeptides that bind to the extracellular binding region of OX40.
    Type: Grant
    Filed: July 23, 1993
    Date of Patent: October 10, 1995
    Assignee: Immunex Corporation
    Inventors: Peter R. Baum, William C. Fanslow, III, Richard B. Gayle, Raymond G. Goodwin