Patents by Inventor Peter R. David

Peter R. David has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240024338
    Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
    Type: Application
    Filed: June 14, 2023
    Publication date: January 25, 2024
    Inventors: Benoit Cardinal-David, Vincent S. Chan, Kassibla E. Dempah, Brian P. Enright, Rodger F. Henry, Raimundo Ho, Ye Huang, Alexander D. Huters, Russell C. Klix, Scott W. Krabbe, Philip R. Kym, Yanbin Lao., Xiaochun Lou, Sean Mackey, Mark A. Matulenko, Peter T. Mayer, Christopher P. Miller, James Stambuli, Valentino J. Stella, Eric A. Voight, Zhi Wang, Geoff G. Zhang
  • Publication number: 20110269185
    Abstract: The present invention provides compositions and methods designed to increase value output of a fermentation reaction that yields a first product, intended for commercialization, such as ethanol, and a fermentation residual used, for example, as animal feed. The methods involve using microorganisms in the fermentation process that have been modified so as to yield a residual having greater value that a residual produced in the process by a microorganism not so modified. In particular, the present invention contemplates using microorganisms in a fermentation process that have been modified to increase production of a nutrient, such as an essential amino acid, thereby reducing the need to supplement the nutrient in the animal's diet. The present invention also provides a modified fermentation residual of higher commercial value. Also provided in the present invention are complete animal feeds, nutritional supplements comprising the subject ferment residuals.
    Type: Application
    Filed: April 27, 2011
    Publication date: November 3, 2011
    Inventor: Peter R. David
  • Publication number: 20110223284
    Abstract: The present invention provides compositions and methods designed to increase value output of a fermentation reaction. In particular, the present invention provides a business method of increasing value output of a fermentation plant. The present invention also provides a modified fermentation residual of higher commercial value. Also provided in the present invention are complete animal feeds, nutritional supplements comprising the subject ferment residuals. Further provided by the present invention is a method of performing fermentation, a modified fermentative microorganism and a genetic vehicle for modifying such microorganism.
    Type: Application
    Filed: October 14, 2010
    Publication date: September 15, 2011
    Applicant: Ambrozea, Inc.
    Inventor: Peter R. David
  • Publication number: 20090291469
    Abstract: The present invention provides compositions and methods designed to increase value output of a fermentation reaction that yields a first product, intended for commercialization, such as ethanol, and a fermentation residual used, for example, as animal feed. The methods involve using microorganisms in the fermentation process that have been modified so as to yield a residual having greater value that a residual produced in the process by a microorganism not so modified. In particular, the present invention contemplates using microorganisms in a fermentation process that have been modified to increase production of a nutrient, such as an essential amino acid, thereby reducing the need to supplement the nutrient in the animal's diet. The present invention also provides a modified fermentation residual of higher commercial value. Also provided in the present invention are complete animal feeds, nutritional supplements comprising the subject ferment residuals.
    Type: Application
    Filed: April 5, 2007
    Publication date: November 26, 2009
    Inventor: Peter R. David
  • Publication number: 20090274659
    Abstract: The present invention provides compositions and methods designed to increase value output of a fermentation reaction. In particular, the present invention provides a business method of increasing value output of a fermentation plant. The present invention also provides a modified fermentation residual of higher commercial value. Also provided in the present invention are complete animal feeds, nutritional supplements comprising the subject ferment residuals. Further provided by the present invention is a method of performing fermentation, a modified fermentative microorganism and a genetic vehicle for modifying such microoganism.
    Type: Application
    Filed: March 20, 2009
    Publication date: November 5, 2009
    Inventor: Peter R. David
  • Publication number: 20090239270
    Abstract: The present invention provides compositions and methods designed to increase value output of a fermentation reaction. In particular, the present invention provides a business method of increasing value output of a fermentation plant. The present invention also provides a modified fermentation residual of higher commercial value. Also provided in the present invention are complete animal feeds, nutritional supplements comprising the subject ferment residuals. Further provided by the present invention is a method of performing fermentation, a modified fermentative microorganism and a genetic vehicle for modifying such microorganism.
    Type: Application
    Filed: September 29, 2008
    Publication date: September 24, 2009
    Inventor: Peter R. David
  • Publication number: 20090171590
    Abstract: The invention encompasses analyzers and analyzer systems that include a single particle analyzer, methods of using the analyzers and analyzers systems to analyze samples, either for single particles or for multiple particles (multiplexing), methods of doing business based on the use of the analyzers or analyzer systems of the system, and electronic media for storing parameters useful in the analyzers and analyzer systems of the invention.
    Type: Application
    Filed: November 21, 2008
    Publication date: July 2, 2009
    Inventors: Robert PUSKAS, Richard A. Livingston, Douglas D. Held, Barbara Klein, Neolle Fukushima, Robert Freese, Philippe J. Goix, Peter R. David, Mickey Urdea
  • Publication number: 20090006280
    Abstract: The present invention provides compositions and methods designed to increase value output of a fermentation reaction. In particular, the present invention provides a business method of increasing value output of a fermentation plant. The present invention also provides a modified fermentation residual of higher commercial value. Also provided in the present invention are complete animal feeds, nutritional supplements comprising the subject ferment residuals. Further provided by the present invention is a method of performing fermentation, a modified fermentative microorganism and a genetic vehicle for modifying such microorganism.
    Type: Application
    Filed: September 11, 2008
    Publication date: January 1, 2009
    Inventor: Peter R. David
  • Publication number: 20080216736
    Abstract: A microfluidic method is provided that comprises: delivering a first fluid to a first lumen of a microfluidic device and a second, different fluid to a second lumen of the microfluidic device, the first and second lumens sharing a common wall which allows for diffusion between the lumens over at least a portion of the length of the lumens; and having the first and second fluids diffuse between the first and second lumens.
    Type: Application
    Filed: May 23, 2008
    Publication date: September 11, 2008
    Applicant: TAKEDA SAN DIEGO, INC.
    Inventor: Peter R. David
  • Publication number: 20080158543
    Abstract: The invention encompasses analyzers and analyzer systems that include a single particle analyzer, methods of using the analyzers and analyzers systems to analyze samples, either for single particles or for multiple particles (multiplexing), methods of doing business based on the use of the analyzers or analyzer systems of the system, and electronic media for storing parameters useful in the analyzers and analyzer systems of the invention.
    Type: Application
    Filed: August 13, 2007
    Publication date: July 3, 2008
    Inventors: Robert Puskas, Richard A. Livingston, Douglas D. Held, Barbara Klein, Noelle Fukushima, Robert Freese, Philippe J. Goix, Peter R. David, Mickey Urdea
  • Patent number: 7309602
    Abstract: The present invention provides compositions and methods designed to increase value output of a fermentation reaction. In particular, the present invention provides a business method of increasing value output of a fermentation plant. The present invention also provides a modified fermentation residual of higher commercial value. Also provided in the present invention are complete animal feeds, nutritional supplements comprising the subject ferment residuals. Further provided by the present invention is a method of performing fermentation, a modified fermentative microorganism and a genetic vehicle for modifying such microoganism.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: December 18, 2007
    Assignee: AmbroZea, Inc.
    Inventor: Peter R. David
  • Patent number: 7158888
    Abstract: A method is provided for identifying a search model to use in molecular replacement for determining a structure of a target biomolecule, such as a protein, from X-ray diffraction data, the method comprising: employing computer executable logic to perform multiple molecular replacement searches on X-ray diffraction data of the target biomolecule where a group of different biomolecule structures are used as search models for the multiple molecular replacement searches; and employing computer executable logic to compare solutions from the multiple molecular replacement searches, the comparison producing data from which biomolecule structures can be identified as having superior structural identity with the target biomolecule as compared to the other biomolecule structures in the group.
    Type: Grant
    Filed: May 4, 2001
    Date of Patent: January 2, 2007
    Assignee: Takeda San Diego, Inc.
    Inventors: Duncan McRee, Peter R. David, Frank von Delft, John Rammelkamp, Enrique Abola
  • Patent number: 7014705
    Abstract: A microfluidic method is provided that comprises: delivering a first fluid to a first lumen of a microfluidic device and a second, different fluid to a second lumen of the microfluidic device, the first and second lumens sharing a common wall which allows for diffusion between the lumens over at least a portion of the length of the lumens; and having the first and second fluids diffuse between the first and second lumens.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: March 21, 2006
    Assignee: Takeda San Diego, Inc.
    Inventor: Peter R. David
  • Patent number: 6994749
    Abstract: A microfluidic device is provided that comprises: a substrate; and a plurality of microvolumes at least partially defined by the substrate, each microvolume comprising a first submicrovolume and a second submicrovolume in fluid communication with the first submicrovolume when the device is rotated about a first rotational axis; wherein rotation of the device about the first rotational axis causes a fixed volume to be transported to each of the second submicrovolumes.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: February 7, 2006
    Assignee: SYRRX, Inc.
    Inventor: Peter R. David
  • Patent number: 6916372
    Abstract: A microfluidic device comprising: a substrate shaped so as to provide the device with an axis of rotation about which the device may be rotated; and a plurality of microvolumes at least partially defined by the substrate, each microvolume comprising a first submicrovolume and a second submicrovolume that is in fluid communication with the first submicrovolume when the device is rotated, the plurality of microvolumes being arranged in the device such that fluid in the first submicrovolumes of multiple of the microvolumes is transported to the second submicrovolumes of the associated microvolumes when the device is rotated about the rotational axis.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: July 12, 2005
    Assignee: Syrrx, Inc.
    Inventor: Peter R. David
  • Patent number: 6872250
    Abstract: A method for determining crystallization conditions for a material, the method comprising: taking a microfluidic device comprising one or more lumens having microvolume dimensions and a plurality of different crystallization samples within the one or more lumens, the plurality of crystallization samples comprising a material to be crystallized and crystallization conditions that vary among the plurality of crystallization samples; transporting the plurality of different crystallization samples within the lumens; and identifying a precipitate or crystal formed in the one or more lumens.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: March 29, 2005
    Assignee: Syrrx, Inc.
    Inventors: Peter R. David, Nathaniel E. David
  • Patent number: 6837926
    Abstract: A microfluidic device is provided that comprises: a card shaped substrate having first and second opposing faces; one or more microvolumes at least partially defined by a first face of the card shaped substrate; and one or more grooves at least partially defined by a second face of the card shaped substrate; wherein a lateral footprint of at least a portion of the one or more grooves overlaps with a lateral footprint of at least one of the one or more microvolumes.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: January 4, 2005
    Assignee: Syrrx, Inc.
    Inventor: Peter R. David
  • Patent number: 6837927
    Abstract: A microfluidic device is provided that comprises: a substrate; and a plurality of microvolumes at least partially defined by the substrate, each microvolume comprising a first submicrovolume and a second submicrovolume that is in fluid communication with the first submicrovolume when the device is rotated, the plurality of microvolumes being arranged in the device such that fluid in the first submicrovolumes of multiple of the microvolumes are transported to second submicrovolumes of the associated microvolumes when the device is rotated.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: January 4, 2005
    Assignee: Syrrx, Inc.
    Inventor: Peter R. David
  • Patent number: 6811609
    Abstract: A microfluidic device is provided that comprises: a substrate; one or more microvolumes at least partially defined by the substrate, each microvolume comprising a first submicrovolume, a second submicrovolume where fluid in the first submicrovolume is transported to the second submicrovolume when the device is rotated about a first rotational axis, and a third submicrovolume where fluid in the first submicrovolume is transported to the third submicrovolume when the device is rotated about a second, different rotational axis.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: November 2, 2004
    Assignee: Syrrx, Inc.
    Inventor: Peter R. David
  • Patent number: 6797056
    Abstract: A microfluidic method is provided that comprises: delivering first and second fluids to a lumen of a microfluidic device such that the first and second fluids flow adjacent to each other within the lumen without mixing except for diffusion at an interface between the first and second fluids, wherein the first fluid is different than the second fluid.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: September 28, 2004
    Assignee: Syrrx, Inc.
    Inventor: Peter R. David