Abstract: The disclosure relates to methods and compositions for regulating expression of DUX4. In some aspects, methods described by the disclosure are useful for treating a disease associated with aberrant DUX4 expression (e.g., facioscapulohumeral muscular dystrophy).

Abstract: A pump monitoring device is configured to be connected to a case drain of a pump. The device includes a manifold having an inlet for connection to the case drain. A flow rate sensor generates a signal indicative of a flow rate of fluid in a fluid path. The flow rate sensor includes a temperature sensor, a heater, and a sensor barrel. The heater heats the sensor barrel while in fluid communication with the fluid. A pressure sensor generates a signal indicative of a pressure of the fluid.

Abstract: A pump monitoring device is configured to be connected to a case drain of a pump. The device includes a manifold having an inlet for connection to the case drain. A flow rate sensor generates a signal indicative of a flow rate of fluid in a fluid path. The flow rate sensor includes a temperature sensor, a heater, and a sensor barrel. The heater heats the sensor barrel while in fluid communication with the fluid. A pressure sensor generates a signal indicative of a pressure of the fluid.

Abstract: A pump monitoring device is configured to be connected to a case drain of a pump. The device includes a manifold having an inlet for connection to the case drain. A flow rate sensor generates a signal indicative of a flow rate of fluid in a fluid path. The flow rate sensor includes a temperature sensor, a heater, and a sensor barrel. The heater heats the sensor barrel while in fluid communication with the fluid. A pressure sensor generates a signal indicative of a pressure of the fluid. There is at least one fault indicator operatively coupled to at least one of the flow rate sensor, the temperature sensor, and the pressure sensor. The fault indicator provides a human perceptible indication that at least one of a sensed flow rate, a sensed temperature, or a sensed pressure of the fluid flowing in the fluid path exceeds a predetermined threshold value.

Abstract: A pump monitoring device is configured to be connected to a case drain of a pump. The device includes a manifold having an inlet for connection to the case drain. A flow rate sensor generates a signal indicative of a flow rate of fluid in a fluid path. The flow rate sensor includes a temperature sensor, a heater, and a sensor barrel. The heater heats the sensor barrel while in fluid communication with the fluid. A pressure sensor generates a signal indicative of a pressure of the fluid. There is at least one fault indicator operatively coupled to at least one of the flow rate sensor, the temperature sensor, and the pressure sensor. The fault indicator provides a human perceptible indication that at least one of a sensed flow rate, a sensed temperature, or a sensed pressure of the fluid flowing in the fluid path exceeds a predetermined threshold value.

Abstract: A pump monitoring device is configured to be connected to a case drain of a pump. The device includes a manifold having an inlet for connection to the case drain. A flow rate sensor generates a signal indicative of a flow rate of fluid in a fluid path. The flow rate sensor includes a temperature sensor, a heater, and a sensor barrel. The heater heats the sensor barrel while in fluid communication with the fluid. A pressure sensor generates a signal indicative of a pressure of the fluid. There is at least one fault indicator operatively coupled to at least one of the flow rate sensor, the temperature sensor, and the pressure sensor. The fault indicator provides a human perceptible indication that at least one of a sensed flow rate, a sensed temperature, or a sensed pressure of the fluid flowing in the fluid path exceeds a predetermined threshold value.

Abstract: A decision engine is provided that integrates all components of a credit application process, including access to and manipulation of credit bureau data, credit scoring, credit decisioning, and matching the correct products, into a single application service provider (ASP) platform which is accessible through a series of Application Programming Interfaces (APIs).

Abstract: A decision engine is provided that integrates all components of a credit application process, including access to and manipulation of credit bureau data, credit scoring, credit decisioning, and matching the correct products, into a single application service provider (ASP) platform which is accessible through a series of Application Programming Interfaces (APIs).

Abstract: In halftone imaging using rotated halftone dot cells, the determination of correspondences between microdots and threshold matrix cells is simplified by leaving the threshold matrices which overlie each halftone dot cell unrotated. Threshold decisions for each microdot in a given horizontal row of a grid proceed in sequence. Each increment along a microdot row within a halftone cell is a unit increment along a horizontal axis of the threshold matrix. Hence, within each halftone cell, two integer additions are sufficient to derive an address of the threshold matrix cell associated with a microdot given the address of the threshold matrix cell associated with the previous microdot.

Abstract: A locking differential comprising a differential carrier1 housing a pair of bevel gears 2, 3 and at least one pinion gear 4 which meshes with the pair of bevel gears, a locking ring 6 positioned within the differential carrier1 between the carrier and one of the bevel gears and splined to the carrier 1 at 7 and 8, locking teeth 9 on the locking ring 6 and corresponding locking teeth 10 on the bevel gear 3, an annular cylinder 12 formed in the carrier 1 and receiving a piston 11 and seal 11 a, the piston 11 being integral with the locking ring whereby the charging of the cylinder 12 with compressed air causes the locking ring 6 to move into its locking position with the teeth 9 engaging the teeth 10 against the action of springs 13 to lock the differential. The locking ring is located within a shaped cover plate C which closes the differential carrier 1 and provides bearing support for the bevel gear 3.