Patents by Inventor Peter Rhode

Peter Rhode has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-15-BASED MOLECULES AND METHODS OF USE THEREOF
    Publication number: 20240307494
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Application
    Filed: June 7, 2024
    Publication date: September 19, 2024
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • IL-15-BASED MOLECULES AND METHODS OF USE THEREOF
    Publication number: 20240307495
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Application
    Filed: June 7, 2024
    Publication date: September 19, 2024
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • METHOD FOR STIMULATING TUMOR-INFILTRATING LYMPHOCYTES WITH AN IL-15:IL-15R COMPLEX
    Publication number: 20240299498
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Application
    Filed: May 30, 2024
    Publication date: September 12, 2024
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • IL-15-BASED MOLECULES AND METHODS OF USE THEREOF
    Publication number: 20240261373
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Application
    Filed: April 18, 2024
    Publication date: August 8, 2024
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • IL-15-BASED FUSIONS TO IL-12 AND IL-18
    Publication number: 20240252609
    Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.
    Type: Application
    Filed: March 20, 2024
    Publication date: August 1, 2024
    Inventors: Warren D. Marcus, Robert Newman, Bai Liu, Lijing You, Lin Kong, Peter Rhode, Hing C. Wong
  • COMPOSITIONS COMPRISING IL-15N72D-BASED MOLECULES AND BACILLUS CALMETTE-GUERIN (BCG)
    Publication number: 20240252591
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Application
    Filed: April 18, 2024
    Publication date: August 1, 2024
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • Compositions comprising IL-15-based molecules and immune checkpoint inhibitor antibodies
    Patent number: 11992516
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Grant
    Filed: October 11, 2022
    Date of Patent: May 28, 2024
    Assignee: Altor Bioscience, LLC.
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • IL-15-based fusions to IL-12 and IL-18
    Patent number: 11975059
    Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.
    Type: Grant
    Filed: December 1, 2023
    Date of Patent: May 7, 2024
    Assignee: Altor Bioscience, LLC.
    Inventors: Warren D. Marcus, Robert Newman, Bai Liu, Lijing You, Lin Kong, Peter Rhode, Hing C. Wong
  • IL-15-BASED MOLECULES AND METHODS OF USE THEREOF
    Publication number: 20240131115
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Application
    Filed: December 22, 2023
    Publication date: April 25, 2024
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • IL-15-BASED FUSIONS TO IL-12 AND IL-18
    Publication number: 20240100138
    Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.
    Type: Application
    Filed: December 1, 2023
    Publication date: March 28, 2024
    Inventors: Warren D. Marcus, Robert Newman, Bai Liu, Lijing You, Lin Kong, Peter Rhode, Hing C. Wong
  • Method for treating neoplasia with an anti-CD38 antibody and an IL-15:IL-15R complex
    Patent number: 11925676
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Grant
    Filed: February 27, 2023
    Date of Patent: March 12, 2024
    Assignee: Altor Bioscience, LLC.
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • MULTIMERIC IL-15 SOLUBLE FUSION MOLECULES AND METHODS OF MAKING AND USING SAME
    Publication number: 20240076354
    Abstract: The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor ?/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus).
    Type: Application
    Filed: October 31, 2023
    Publication date: March 7, 2024
    Inventors: Hing C. Wong, Peter Rhode, Bai Liu, Xiaoyun Zhu, Kai-Ping Han
  • Method of treating cancer with composition comprising IL-15-based molecules and BCG
    Patent number: 11890323
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Grant
    Filed: December 9, 2022
    Date of Patent: February 6, 2024
    Assignee: Altor Bioscience, LLC
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • IL-15-based fusions to IL-12 and IL-18
    Patent number: 11872272
    Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.
    Type: Grant
    Filed: February 13, 2023
    Date of Patent: January 16, 2024
    Assignee: Altor Bioscience, LLC
    Inventors: Warren D. Marcus, Robert Newman, Bai Liu, Lijing You, Lin Kong, Peter Rhode, Hing C. Wong
  • Multimeric IL-15 soluble fusion molecules and methods of making and using same
    Patent number: 11845783
    Abstract: The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor ?/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus).
    Type: Grant
    Filed: July 26, 2021
    Date of Patent: December 19, 2023
    Assignee: Altor Bioscience, LLC.
    Inventors: Hing C. Wong, Peter Rhode, Bai Liu, Xiaoyun Zhu, Kai-Ping Han
  • FUSION MOLECULES AND IL-15 VARIANTS
    Publication number: 20230257437
    Abstract: The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making the proteins. The instant invention additionally provides methods of stimulating or suppressing immune responses in a mammal using the fusion protein complexes and IL-15 variants of the invention.
    Type: Application
    Filed: April 24, 2023
    Publication date: August 17, 2023
    Inventors: Hing C. Wong, Peter Rhode, Xiaoyun Zhu, Kai-Ping Han
  • IL-15-BASED FUSIONS TO IL-12 AND IL-18
    Publication number: 20230248813
    Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.
    Type: Application
    Filed: February 13, 2023
    Publication date: August 10, 2023
    Inventors: Warren D. Marcus, Robert Newman, Bai Liu, Lijing You, Lin Kong, Peter Rhode, Hing C. Wong
  • IL-15-BASED MOLECULES AND METHODS OF USE THEREOF
    Publication number: 20230241175
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Application
    Filed: February 28, 2023
    Publication date: August 3, 2023
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • IL-15-BASED MOLECULES AND METHODS OF USE THEREOF
    Publication number: 20230241174
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Application
    Filed: December 9, 2022
    Publication date: August 3, 2023
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • IL-15-BASED MOLECULES AND METHODS OF USE THEREOF
    Publication number: 20230233649
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Application
    Filed: February 27, 2023
    Publication date: July 27, 2023
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong