Abstract: The present invention relates to a novel and improved process for preparing (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluo-romethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid of the formula (I) and to novel crystalline forms of it, which is i.a. the pseudopolymorphic form monohydrate I (I-M-I) or the pseudopolymorphic form monohydrate II (I-M-II), furthermore the present invention relates to a novel and selective crystallization process for preparation of the pseudopolymorphic form monohydrate I (I-M-I) or the pseudopolymorphic form monohydrate II (I-M-II), preferably monohydrate I of formula (I-M-I) and to pharmaceutical compositions comprising monohydrate I of formula (I-M-I) and to its use for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of pulmonary and cardiopulmonary and cardiovascular diseases.

Abstract: Container with a membrane packaging for medical objects, consisting of at least one cover which is connectable to a lower part, wherein at least one clamping membrane is circumferentially and peripherally attached to at least one container part, and the object to be protected lies upon the at least one clamping membrane and is borne by it, wherein only one clamping membrane, is given, which lies opposite to a fixed holding slot for holding the object on the other container part and an additional pretensioning can be applied to the clamping membrane upon closing of the container.

Abstract: Medical packaging for the sterile storage of medical articles in a hermetically and sterile sealable packaging sleeve. The packing generally includes at least two parts, with a sealed, film-like outer packaging, which at least partially encloses the packaging sleeve in a form-fitting manner and provides a pressure that is reduced with respect to the atmosphere. At least one end face of the packaging sleeve may be designed to be flattened, wherein a length of the outer packaging is generally longer than a length of the packaging sleeve and projects beyond the end face region of the packaging sleeve. A sealing or welding seam may be arranged at least in the end face region of the packaging sleeve, wherein at least one of the end faces of the packaging sleeve, preferably both end faces, are designed so as to be flattened off. The end-sided transition from the packaging sleeve into the outer packaging is substantially wrinkle free.

Abstract: The present disclosure relates to a monitoring system for an electrochemical sensor, comprising: a first measuring point having a first measuring medium, a first electrochemical sensor that is in contact with the first measuring medium and is suitable for generating first sensor data, an electronic unit which is connected to the first electrochemical sensor and has a data memory, the electronic unit being suitable for storing the first sensor data generated by the first electrochemical sensor in the data memory, a computing unit adapted to be connected to the electronic unit for reading out the first sensor data in the data memory, the computing unit being connected to a database and the database having second sensor data of second electrochemical sensors, the second electrochemical sensors being structurally identical to the first electrochemical sensor.

Abstract: Packaging sleeve for medical purposes for storing sterile objects (25, 45), consisting of at least one outer sleeve (2) that is open at one end and can be sealed with a sealing closure (10) and has an inner sleeve (12) accommodated in it with a clamping effect, wherein the inner sleeve (12) is accommodated in a clamping seating in a receiving opening (15) in the sealing closure (10) on the bottom side of the outer sleeve (2) and the clamping seat thereby formed presses the sealing ribs (7, 55, 56, 59) arranged on the outside circumference of the sealing closure (10) against the inside of the outer sleeve (2) under increased contact pressure (FIG. 1).

Abstract: Container with a membrane packaging for medical objects, consisting of at least one cover which is connectable to a lower part, wherein at least one clamping membrane is circumferentially and peripherally attached to at least one container part, and the object to be protected lies upon the at least one clamping membrane and is borne by it, wherein only one clamping membrane, is given, which lies opposite to a fixed holding slot for holding the object on the other container part and an additional pretensioning can be applied to the clamping membrane upon closing of the container.

Abstract: Packaging sleeve for medical purposes for storing sterile objects (25, 45), consisting of at least one outer sleeve (2) that is open at one end and can be sealed with a sealing closure (10) and has an inner sleeve (12) accommodated in it with a clamping effect, wherein the inner sleeve (12) is accommodated in a clamping seating in a receiving opening (15) in the sealing closure (10) on the bottom side of the outer sleeve (2) and the clamping seat thereby formed presses the sealing ribs (7, 55, 56, 59) arranged on the outside circumference of the sealing closure (10) against the inside of the outer sleeve (2) under increased contact pressure (FIG. 1).

Abstract: Packaging sleeve for medical purposes for storing sterile objects (25, 45), consisting of at least one outer sleeve (2) that is open at one end and can be sealed with a sealing closure (10) and has an inner sleeve (12) accommodated in it with a clamping effect, wherein the inner sleeve (12) is accommodated in a clamping seating in a receiving opening (15) in the sealing closure (10) on the bottom side of the outer sleeve (2) and the clamping seat thereby formed presses the sealing ribs (7, 55, 56, 59) arranged on the outside circumference of the sealing closure (10) against the inside of the outer sleeve (2) under increased contact pressure (FIG. 1).

Abstract: Medical packaging for the sterile storage of medical articles in a hermetically and sterile sealable packaging sleeve. The packing generally includes at least two parts, with a sealed, film-like outer packaging, which at least partially encloses the packaging sleeve in a form-fitting manner and provides a pressure that is reduced with respect to the atmosphere. At least one end face of the packaging sleeve may be designed to be flattened, wherein a length of the outer packaging is generally longer than a length of the packaging sleeve and projects beyond the end face region of the packaging sleeve. A sealing or welding seam may be arranged at least in the end face region of the packaging sleeve, wherein at least one of the end faces of the packaging sleeve, preferably both end faces, are designed so as to be flattened off. The end-sided transition from the packaging sleeve into the outer packaging is substantially wrinkle free.

Abstract: Package block (3, 5) consisting of individual packages (1, 2) that are mechanically coupled together and can be separated from one another by a shear force acting along the respective parting joint (11) and can be sealed medically tight at least in the vicinity of their container openings (14) by a continuous label strip (17), wherein the continuous label strip (17) consists of individual labels (18-20) connected to one another across parting edges (32), and that the parting edges (32) are aligned with the parting joints (11) between the individual packages (1, 2).

Abstract: A packaging sleeve (2) having at least one latching cap (1) arranged on the end. The shape of the latching cap is adapted according to the outer perimeter of the packaging sleeve (2) and securely attached to the packaging sleeve by its side walls (13) by a latching wall (15).

Abstract: Package for elongated sharp-edged objects, in particular for tools useful for surgical applications, which are secured in a fixed position in a package consisting at least partially of plastic, wherein the package comprises an a first enlarged package part which defines an interior into which the object that is to be protected and secured protrudes with its sharp edges in a noncontact manner and a second package part in which the shaft of the object is accommodated and held in a fixed position by holding elements.

Abstract: Packaging and methods for packaging tools having a sharp or cutting edge, such as surgical tools, in which the tool is packaged under sterile conditions. The tool may be packaged first—at least partially—and in particular with its sensitive cutting edges and working surfaces packaged in a protective package. The protective package containing at least the cutting or working surfaces of the tool may then be secured in a fixed position in an outer blister pack, which may be sealed with a sealing film.

Abstract: Package block (3, 5) consisting of individual packages (1, 2) that are mechanically coupled together and can be separated from one another by a shear force acting along the respective parting joint (11) and can be sealed medically tight at least in the vicinity of their container openings (14) by a continuous label strip (17), wherein the continuous label strip (17) consists of individual labels (18-20) connected to one another across parting edges (32), and that the parting edges (32) are aligned with the parting joints (11) between the individual packages (1, 2).

Abstract: Packaging for elongate objects such as a screw (20, 30) having a head (21) of enlarged diameter and a bolt part (23, 24) having reduced diameter. The packaging (1) includes a packaging sleeve that is open at at least one end and that is made of an elastically bendable material. The packaging sleeve has at least one upper insertion opening (2) and securely holds the head (21) of the object screw (20) in an axial direction in an elastically expandable clamping collar (5) that is adjacent to the insertion opening (2) and maintains the bolt-side end of the object at a distance from the inside of the plastic packaging.

Abstract: A flexible safety cap (1) for accommodating any tool (13, 14) among a group of tools having different diameters or different geometries, said cap having a terminating front wall (10) and an oppositely disposed clamping opening (8, 8?) with at least one non-round, acting clamping profile (5, 5?, 5?, 5??, 5??) wherein at least one slot (9) that penetrates through the wall of the safety cap (1) is disposed in the vicinity of the front wall (10) to establish an elastic, resilient clamping connection between an outside circumference of the tool (13, 14) and an inside wall of the safety cap (1).

Abstract: The impact protection cap manufactured from a bendable synthetic material comprises at least one middle shell (3), connected in the forehead area of the wearer by means of flexible areas (12, 13) to lateral shells (1, 2) appended to the sides thereof, characterized in that the lateral shells (1, 2) extend at least partially over the middle shell (3) thereby building overlapping areas (22, 22?) wherebetween ventilation slots (7, 8) are formed.

Abstract: Packaging sleeve for medical purposes for storing sterile objects (25, 45), consisting of at least one outer sleeve (2) that is open at one end and can be sealed with a sealing closure (10) and has an inner sleeve (12) accommodated in it with a clamping effect, wherein the inner sleeve (12) is accommodated in a clamping seating in a receiving opening (15) in the sealing closure (10) on the bottom side of the outer sleeve (2) and the clamping seat thereby formed presses the sealing ribs (7, 55, 56, 59) arranged on the outside circumference of the sealing closure (10) against the inside of the outer sleeve (2) under increased contact pressure (FIG. 1).

Abstract: A packaging container for elongated objects that includes an outer sleeve (1) with at least one threaded section (4) and an inner sleeve (2) with at least one toothed or threaded strip (3) that can be brought into threaded engagement with the threaded section (4) such that the inner sleeve can be screwed into the interior of the outer sleeve (1). The at least one threaded section (4) is interrupted by at least one sliding strip (5) that is aligned in the longitudinal direction of said packaging container and that interrupts the threaded section (4), the width of the sliding strip (5) being greater than the width of the toothed or threaded strip (3).

Abstract: The invention relates to individual packaging for elongate objects (20, 30) that consist of at least a head (21) of enlarged diameter and a bolt part (23, 24) adjoining the head and having reduced diameter, such as bone pins, ejector pins, and the like, wherein the individual packaging (1) consists of an approximately cylindrical packaging sleeve, which is open at an end face at least at one end and is made of an elastically bendable material, said packaging sleeve having at least one upper insertion opening (2) for inserting the elongate object (20, 30), wherein the individual packaging (1) holds in a positionally secured manner only the head (21) of the object (20) to be held in an elastically expandable clamping collar (5) adjacent to the insertion opening (2); in an axial direction and the bolt-side end of the object is held at a distance from the inside of the plastic packaging in such a way that distance is maintained.