Abstract: A hearing protection device includes: a sub-band splitting module configured to divide a first microphone input signal into sub-band signals having a first sub-band signal and a second sub-band signal; an estimator module configured to estimate signal strength parameters of respective sub-band signals, the signal strength parameters having a first signal strength parameter of the first sub-band signal, and a second signal strength parameter of the second sub-band signal; a multiband limiter; and a limiter controller; wherein the limiter controller is configured to determine gain reductions for the sub-band signals of the first microphone input signal, the gain reductions having a first gain reduction and a second gain reduction, and wherein the limiter controller is configured to control the multiband limiter to apply the second gain reduction to the second sub-band signal, wherein the second gain reduction for the second sub-band signal is based on the first signal strength parameter.

Abstract: A hearing protection device includes: a sub-band splitting module configured to divide a first microphone input signal into sub-band signals having a first sub-band signal and a second sub-band signal; an estimator module configured to estimate signal strength parameters of respective sub-band signals, the signal strength parameters having a first signal strength parameter of the first sub-band signal, and a second signal strength parameter of the second sub-band signal; a multiband limiter; and a limiter controller; wherein the limiter controller is configured to determine gain reductions for the sub-band signals of the first microphone input signal, the gain reductions having a first gain reduction and a second gain reduction, and wherein the limiter controller is configured to control the multiband limiter to apply the second gain reduction to the second sub-band signal, wherein the second gain reduction for the second sub-band signal is based on the first signal strength parameter.

Abstract: The present invention provides compounds of Formula 1, or a pharmaceutically acceptable salt thereof, where R, R1, and G are as described herein; methods of preparing the compounds; and use of the compounds to treat pain and/or inflammation associated with arthritis or osteoarthritis.

Abstract: The present invention provides a compound of the Formula I: wherein A is: and W, Y, X, R1, R2, R3, and R4 are as defined herein, or a pharmaceutically acceptable salt thereof, for use as an inhibitor of the EP4 receptor.

Abstract: The present invention provides compounds of Formula (1), or a pharmaceutically acceptable salt thereof, formula (1), where R, R1, and G are as described herein; methods of preparing the compounds; and use of the compounds to treat pain and/or inflammation associated with arthritis or osteoarthritis.

Abstract: The present invention provides compounds of Formula (1), or a pharmaceutically acceptable salt thereof, formula (1), where R, R1, and G are as described herein; methods of preparing the compounds; and use of the compounds to treat pain and/or inflammation associated with arthritis or osteoarthritis.

Abstract: The present invention provides a compound of the Formula (I): wherein X, R, R1, R2, R3, R4, R5, R6, R7, R8, and R9 are as defined herein, or a pharmaceutically acceptable salt thereof.

Abstract: The present invention provides a compound of the Formula (I): wherein X, R, R1, R2, R3, R4, R5, R6, R7, R8, and R9 are as defined herein, or a pharmaceutically acceptable salt thereof.

Abstract: The present invention provides a compound of the Formula I: wherein A is: and W, Y, X, R1, R2, R3, and R4 are as defined herein, or a pharmaceutically acceptable salt thereof, for use as an inhibitor of the EP4 receptor.

Abstract: The present invention provides a compound of the Formula I: or a pharmaceutically acceptable salt thereof.

Abstract: The present application is directed in particular to a power adapter, adapted to be connected on the one hand to a power interface of a cordless power tool and adapted to be connected on the other hand to an energy source, in particular mobile energy source, for electrically power the power tool via the power adapter.

Abstract: The present invention provides a compound of the Formula I: or a pharmaceutically acceptable salt thereof.

Abstract: A hand-guided apparatus may include an operating lever, a switch, and an intermediate lever. The operating lever may actuate a function of the hand-guided apparatus, be constructed in an elongated manner and be pivotably attached to a housing of the apparatus. The switch actuates the function and is arranged in the housing. The intermediate lever mechanically actuates the switch. The operating lever includes a safety element enabled to be pretensioned and shifted along a longitudinal axis of the operating lever. The operating lever and the intermediate lever are enabled to be mechanically coupled by shifting the safety element into a pretensioned state to enable actuation of the switch by pivoting of the operating lever. The operating lever and the intermediate lever are enabled to be mechanically decoupled by shifting the safety element into a relaxed state to prevent actuation of the switch by pivoting of the operating lever.

Abstract: Compounds of formula (I): formula (I) wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and diseases related to dyslipidemia.

Abstract: A method is proposed for the solidification of a non-metal melt (130) which is located in a crucible (120) arranged in the device (100), wherein the device (100) has a multiplicity of inductors (100) for the creation of magnetic fields. By feeding in a first set of phase-displaced alternating currents (I1a, I2b, I3c, I4d) having a first frequency (f1), a first travelling field (W1) is created in the melt (130). By feeding in at least one second set of phase-displaced alternating currents (I2a, I2b, I3c, I4d) having a second frequency (f2), a second travelling field (W2) is created in the melt (130) which is directed against the first travelling field (W1), wherein the inductors (100) are arranged on the crucible (120) in a vertically extending arrangement, so that the alternating fields created (W1, W2) pass through the melt (130) in vertical direction (Y) and have a flow force minimum on the crucible or vessel wall.

Abstract: Compounds of formula and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.

Abstract: Compounds of formula wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.

Abstract: Compounds of formula (I): formula (I) wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and diseases related to dyslipidemia.

Abstract: Compounds of formula wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.

Abstract: Compounds of formula. wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.