Patents by Inventor Peter Rupert

Peter Rupert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-CD90 ANTIBODIES, BINDING FRAGMENTS, AND USES THEREOF
    Publication number: 20250249125
    Abstract: Anti-CD90 antibodies, binding fragments, and uses thereof are described. The provided antibodies and binding fragments can be used to isolate CD90 cells or to target such cells ex vivo or in vivo for a research, a diagnostic, or a therapeutic purpose. Anti-CD90 antibodies and binding fragments thereof can also be used in engineered formats to create antibody conjugates or within a recombinant protein to pseudotype viral vectors.
    Type: Application
    Filed: March 22, 2023
    Publication date: August 7, 2025
    Applicant: Fred Hutchison Cancer Center
    Inventors: Hans-Peter Kiem, Stefan Radtke, Kurt Berckmueller, Roland K. Strong, Peter Rupert
  • Chelating platform for delivery of radionuclides
    Patent number: 12257325
    Abstract: Siderocalin-metal chelator combinations that bind metallic radioisotopes used in nuclear medicine with high affinity are described. The high affinity siderocalin-metal chelator combinations include a number of chelator backbone arrangements with functional groups that coordinate with metals. The siderocalin-metal chelator combinations can be used to deliver radionuclides for imaging and therapeutic purposes.
    Type: Grant
    Filed: December 10, 2021
    Date of Patent: March 25, 2025
    Assignees: Fred Hutchinson Cancer Research Center, The Regents of the University of California
    Inventors: Roland K. Strong, Peter Rupert, Rebecca J. Abergel, Ilya Captain, Gauthier J P Deblonde
  • CHELATING PLATFORM FOR DELIVERY OF RADIONUCLIDES
    Publication number: 20220160904
    Abstract: Siderocalin-metal chelator combinations that bind metallic radioisotopes used in nuclear medicine with high affinity are described. The high affinity siderocalin-metal chelator combinations include a number of chelator backbone arrangements with functional groups that coordinate with metals. The siderocalin-metal chelator combinations can be used to deliver radionuclides for imaging and therapeutic purposes.
    Type: Application
    Filed: December 10, 2021
    Publication date: May 26, 2022
    Applicants: Fred Hutchinson Cancer Research Center, The Regents of the University of California
    Inventors: Roland K. Strong, Peter Rupert, Rebecca J. Abergel, Ilya Captain, Gauthier JP Deblonde
  • Chelating platform for delivery of radionuclides
    Patent number: 11235076
    Abstract: Siderocalin-metal chelator combinations that bind metallic radioisotopes used in nuclear medicine with high affinity are described. The high affinity siderocalin-metal chelator combinations include a number of chelator backbone arrangements with functional groups that coordinate with metals. The siderocalin-metal chelator combinations can be used to deliver radionuclides for imaging and therapeutic purposes.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: February 1, 2022
    Assignees: Fred Hutchinson Cancer Research Center, The Regents of the Universitv of California
    Inventors: Roland K. Strong, Peter Rupert, Rebecca J. Abergel, Ilya Captain, Gauthier J P Deblonde
  • NKG2D decoys
    Patent number: 10815290
    Abstract: Single chain, multimerized, and/or glycosylated NKG2D decoys are described. The NKG2D decoys have high affinity and avidity for surface bound and soluble NKG2D ligands and can be used to (i) identify NKG2D ligands; (ii) treat cancer, graft vs. host disease (GVHD), and inflammatory conditions; and (iii) potentiate an immune response against a vaccine as well as many other potential uses.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: October 27, 2020
    Assignee: FRED HUTCHINSON CANCER RESEARCH CENTER
    Inventors: Mesfin Gewe, Roland K. Strong, Martin Prlic, Peter Rupert, Thomas Spies, Veronika Spies
  • CHELATING PLATFORM FOR DELIVERY OF RADIONUCLIDES
    Publication number: 20190184041
    Abstract: Siderocalin-metal chelator combinations that bind metallic radioisotopes used in nuclear medicine with high affinity are described. The high affinity siderocalin-metal chelator combinations include a number of chelator backbone arrangements with functional groups that coordinate with metals. The siderocalin-metal chelator combinations can be used to deliver radionuclides for imaging and therapeutic purposes.
    Type: Application
    Filed: August 28, 2017
    Publication date: June 20, 2019
    Applicants: Fred Hutchinson Cancer Research Center, The Regents of the University of California
    Inventors: Roland K. Strong, Peter Rupert, Rebecca J. Abergel, Ilya Captain, Gauthier JP Deblonde
  • NKG2D DECOYS
    Publication number: 20180371051
    Abstract: Single chain, multimerized, and/or glycosylated NKG2D decoys are described. The NKG2D decoys have high affinity and avidity for surface bound and soluble NKG2D ligands and can be used to (i) identify NKG2D ligands; (ii) treat cancer, graft vs. host disease (GVHD), and inflammatory conditions; and (iii) potentiate an immune response against a vaccine as well as many other potential uses.
    Type: Application
    Filed: November 10, 2016
    Publication date: December 27, 2018
    Applicant: Fred Hutchinson Cancer Research Center
    Inventors: Roland K. Strong, Mesfin Gewe, Martin Prlic, Peter Rupert, Thomas Spies, Veronika Spies
  • Crystalline phosphatase and method for use thereof
    Publication number: 20060173633
    Abstract: This disclosure is directed to a crystalline form of a human protein tyrosine phosphatase designated cdc14A and more particularly to a crystal of human cdc14A, a method of crystallization thereof, and its structure, obtained by x-ray diffraction. In addition, the disclosure relates to methods of identifying new PTP binding agents and more particularly cdc14 (A or B) substrates and inhibitors.
    Type: Application
    Filed: January 27, 2006
    Publication date: August 3, 2006
    Applicant: Ceptyr, Inc.
    Inventor: Peter Rupert