Patents by Inventor Peter S. Dragovich

Peter S. Dragovich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF INHIBITING HEPATITUS C VIRUS BY COMBINATION OF A 5,6-DIHYDRO-1H-PYRIDIN-2-ONE AND ONE OR MORE ADDITIONAL ANTIVIRAL COMPOUNDS
    Publication number: 20140066396
    Abstract: The invention is directed to a method of treating infections by hepatitis C virus by administering N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1?6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide and one or more additional antiviral compounds or pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: November 8, 2013
    Publication date: March 6, 2014
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Peter S. Dragovich, Peggy A. Thompson, Frank Ruebsam
  • Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
    Patent number: 6872745
    Abstract: Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.
    Type: Grant
    Filed: May 12, 2003
    Date of Patent: March 29, 2005
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Theodore O. Johnson, Jr., Ye Hua, Hiep T. Luu, Peter S. Dragovich
  • Antipicornaviral compounds and compositions, their uses, and materials for their synthesis
    Publication number: 20030225042
    Abstract: Compounds of the formula: 1
    Type: Application
    Filed: May 12, 2003
    Publication date: December 4, 2003
    Inventors: Theodore O. Johnson, Ye Hua, Hiep T. Luu, Peter S. Dragovich
  • Antipicornaviral compounds, compositions containing them, and methods for their use
    Patent number: 6649639
    Abstract: Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses.
    Type: Grant
    Filed: September 7, 2001
    Date of Patent: November 18, 2003
    Inventors: Peter S. Dragovich, Thomas J. Prins, Ru Zhou
  • Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
    Patent number: 6610730
    Abstract: Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.
    Type: Grant
    Filed: April 12, 2001
    Date of Patent: August 26, 2003
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Theodore O. Johnson Jr., Ye Hua, Hiep T. Luu, Peter S. Dragovich
  • Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
    Patent number: 6514997
    Abstract: Compounds of the formula: where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the picornaviral 3C protease. Also disclosed are compounds of the formula: where the formula variables are as defined herein that advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as rhinovirus 3C proteases. Intermediates and synthetic methods for preparing such compounds are also described.
    Type: Grant
    Filed: December 1, 2000
    Date of Patent: February 4, 2003
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Peter S. Dragovich, Thomas J. Prins, Ru Zhou, Theodore O. Johnnson, Jr.
  • Antipicornaviral compounds and methods for their use and preparation
    Patent number: 6362166
    Abstract: Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of picornaviral 3C proteases. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses. Several novel methods and intermediates can be used to prepare the novel picornaviral 3C protease inhibitors of the present invention.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: March 26, 2002
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Stephen E. Webber, Peter S. Dragovich, Thomas J. Prins, Siegfried H. Reich, Thomas L. Little, Jr., Ethel S. Littlefield, Joseph T. Marakovits, Robert E. Babine, Ted M. Bleckman
  • Antipicornaviral compounds, compositions containing them, and methods for their use
    Publication number: 20020032237
    Abstract: Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses.
    Type: Application
    Filed: September 7, 2001
    Publication date: March 14, 2002
    Inventors: Peter S. Dragovich, Thomas J. Prins, Ru Zhou
  • Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
    Publication number: 20020006943
    Abstract: Compounds of the formula: 1
    Type: Application
    Filed: April 12, 2001
    Publication date: January 17, 2002
    Inventors: Theodore O. Johnson , Jr., Ye Hua, Hiep T. Luu, Peter S. Dragovich
  • Antipicornaviral compounds, compositions containing them, and methods for their use
    Patent number: 6331554
    Abstract: Picornaviral 3C protease inhibitors of formula I, obtainable by chemical synthesis, that inhibit or block the biological activity of the picornaviral 3C protease are described. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: December 18, 2001
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Peter S. Dragovich, Thomas J. Prins, Ru Zhou
  • Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
    Publication number: 20010047006
    Abstract: Compounds of the formula: 1
    Type: Application
    Filed: December 1, 2000
    Publication date: November 29, 2001
    Inventors: Peter S. Dragovich, Thomas J. Prins, Ru Zhou, Theodore O. Johnnson
  • Antipicornaviral compounds and methods for their use and preparation
    Patent number: 6214799
    Abstract: Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of picornaviral 3C proteases. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses. Several novel methods and intermediates can be used to prepare the novel picornaviral 3C protease inhibitors of the present invention.
    Type: Grant
    Filed: January 7, 1999
    Date of Patent: April 10, 2001
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Stephen E. Webber, Peter S. Dragovich, Thomas J. Prins, Siegfried H. Reich, Thomas L. Little, Jr., Ethel S. Littlefield, Joseph T. Marakovits, Robert E. Babine, Ted M. Bleckman
  • Antipicornaviral compounds compositions containing them and methods for their use
    Patent number: 6020371
    Abstract: Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses.
    Type: Grant
    Filed: December 16, 1997
    Date of Patent: February 1, 2000
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Peter S. Dragovich, Thomas J. Prins, Ru Zhou
  • Antipicornaviral compounds and methods for their use and preparation
    Patent number: 5962487
    Abstract: Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of picornaviral 3C proteases. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses. Several novel methods and intermediates can be used to prepare the novel picornaviral 3C protease inhibitors of the present invention.
    Type: Grant
    Filed: December 16, 1997
    Date of Patent: October 5, 1999
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Stephen E. Webber, Peter S. Dragovich, Thomas J. Prins, Ethel S. Littlefield, Joseph T. Marakovits, Robert E. Babine
  • Antipicornaviral compounds and methods for their use and preparation
    Patent number: 5856530
    Abstract: Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of picornaviral 3C proteases. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses. Several novel methods and intermediates can be used to prepare the novel picornaviral 3C protease inhibitors of the present invention.
    Type: Grant
    Filed: May 2, 1997
    Date of Patent: January 5, 1999
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Stephen E. Webber, Peter S. Dragovich, Thomas J. Prins, Siegfried H. Reich, Thomas L. Little, Jr., Ethel S. Littlefield, Joseph T. Marakovits, Robert E. Babine, Ted M. Bleckman