Abstract: The present invention provides for a composition, for augmentation and regeneration of living tissue in a subject, comprising a population of porous microparticles of a biodegradable polymer, one or more mammalian cell populations, and optionally, a biocompatible adhesive.

Abstract: The present invention provides for a composition, for augmentation and regeneration of living tissue in a subject, comprising a population of porous microparticles of a biodegradable polymer, one or more mammalian cell populations, and optionally, a biocompatible adhesive.

Abstract: An isolated, acellular biosynthetic cartilaginous matrix substantially devoid of synthetic biodegradable scaffold structure is provided. Through a method with the steps of a) contacting in vitro a population of chondrogenic cells with a synthetic biodegradable scaffold; b) culturing in vitro for a period of time said chondrogenic cells within said synthetic biodegradable scaffold so that the chondrogenic cells produce a biosynthetic cartilaginous matrix; c) substantially removing any antigen derived from said chondrogenic cells a matrix suitable of implantation into a living individual mammal, such as a human being is obtained.

Abstract: The present invention provides for a composition, for augmentation and regeneration of living tissue in a subject, comprising a population of porous microparticles of a biodegradable polymer, one or more mammalian cell populations, and optionally, a biocompatible adhesive.

Abstract: The present invention relates to a hydrophilic coating of a water-swellable hydrophilic matrix having incorporated therein an anti-microbial polymer, said anti-microbial polymer carrying pendant groups providing the anti-microbial effect, said pendant groups being selected from primary amino groups, secondary amino groups, tertiary amino groups, quaternary ammonium groups, imino groups, and phosphonium groups.

Abstract: The present invention relates to a pressure sensitive adhesive composition comprising a rubbery elastomeric matrix, said composition comprising one or more amphiphilic block copolymers and the use thereof for application in the medical field for instance for adhering of medical devices to the skin, in wound dressings or ostomy appliances and provides a quick and safe means for managing perspiration from the skin also when occluded with medical appliances.

Abstract: The present invention provides novel compositions for transdermal delivery of at least one immunogen to an individual, which compositions comprise (a) said at least one immunogen (b) an occlusion vehicle and (c) an immunogen delivery system in the form of a PosIntro or a cationic ISCOM or comprising at least one saponin and at least one sterol, as well as a process for preparation of the compositions. The invention further provides constructs comprising these compositions. The compositions and constructs may be used in methods for generating an immunological response, methods for treating or preventing a condition of illness and methods for vaccination. The occlusion vehicle is e.g. a pressure sensitive adhesive, such as a hydrocolloid adhesive or a hydrogel adhesive, which may be cross-linked, or the occlusion vehicle may be non-adherent.

Abstract: An adhesive, flat skin barrier product for use as semi-manufacture in the production of, a.o., dressings, wound-care devices, electrodes and fastening means for ostomy equipment and catheters, consists of alternating zones of material of at least two different kinds (26,28,30) at least one of which is a skinfriendly self-adhesive material. The zones are parallel and extend in a direction usually at right angles to the main surfaces of the product. The zones may for instance be parallel strips, co-axial rings, co-wound Archimedean spirals or short strands.The skin barrier product offers the advantage that in a simple way it may be produced to comprise, besides the sealing material itself, other components for special purposes, e.g. having contents of antiseptics, medicaments or others biologically active substances of liquid-transporting or electrically conductive structures.

Abstract: A dressing comprising a dressing containing a water-soluble or water-swellable hydrocolloid, a water-insoluble, viscous, elastomeric binder and optionally also a tackifier resin, is bevelled along all outer edges and optionally also, if annular, along the inner edge.

Abstract: Return valve for a bag (1) for collecting liquid excretions from a human body, which valve comprises a valve flap (9,10) made of flexible film and placed between a reservoir portion (8) of the bag and a portion having a coupling to be connected with corresponding fastening means placed around an opening in the body. In order to ensure an extreme security against leakage through the return valve, the return valve further comprises a second valve flap (13, 14) arranged downstream of the first valve in the direction of the flow of the liquid secretions, which second valve flap comprises a film portion passing the opening (at 11) of the first valve, and together with the valve flap of the first valve forming a passage to the region between the first and second valves.

Abstract: A dispenser for dispensing a laminated web (24) comprising a flexible, adhesive layer (12) having a certain thickness surrounded by a first and a second relatively stiff protective sheet (14,18). The dispenser comprises a holder, e.g. a housing (2), for a first roll (4) and a second roll (8) with a press slot (16) serving as an outlet guide means. The rolls and the press slots are arranged to permit simultaneous moving of a first web (5) comprising the adhesive layer (12) and the first protective sheet (14), and a second web consisting of the second protective sheet (18) from the first and the second rolls, respectively, and through the press slot.The dispenser permits dispensing of the laminated web, although the web cannot be stored as a roll.

Abstract: In a deodorizing gas filter for ostomy bags (22), consisting of a sheet (10) of deodorizing filter material, for example a porous foamed plastic with particles of active carbon, and having a central inlet opening (12), a gas-tight connecting layer (14) to the bag on one side of the filter sheet, and a gas-tight covering layer (24) on the other side of the filter sheet, the covering layer consists of elastic film material, or is provided with a layer of elastic material at least in that part covering the central opening and an immediately surrounding zone thereof.

Abstract: A skin barrier consisting of an elastic film (16), secured to the film a layer (18) of at least weakly elastic adhesive material, these two components together having low resistance to quick deformation and rapid recovery to substantially the original shape after deformation, the plastic properties of the adhesive thereby being compensated by the elasticity of the film. Optionally there may be a releasable protective cover (20,22) on the other side of the adhesive layer. The adhesive material consists of a hydrocolloid, preferably sodium carboxymethylcellulose, dispersed in a continuous phase consisting of a mixture of (a) a physically cross-linked elastomer which is a styrene-olefin-styrene block copolymer, (b) a hydrocarbon resin tackifier which is a polymer or copolymer of cyclopentadiene, dicyclopentadiene or .alpha.- or .beta.