Patents by Inventor Peter Schadewaldt

Peter Schadewaldt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the determination of .alpha.-ketoisocaproate in biological samples using D-.alpha.-hydroxyisocaproic dehydrogenase from lactobacillus casei
    Patent number: 5264347
    Abstract: The selective determination of .alpha.-ketoisocaproate in samples of body fluids, especially in serum, is achieved, without previous separation, directly in the fluid and in the presence of NADH, by means of a KIC-specific D-.alpha.-hydroxy-isocaproic dehydrogenase that originates specifically from strains of Lactobacillus casei producing this enzyme, in particular strains of Lactobacillus casei subspecies pseudoplantarum or casei. The KIC determination is used, in particular, for diagnosing maple syrup urine disease. Expedient for this purpose are analytical kits which have a divisible stock of D-.alpha.-hydroxyisocaproic dehydrogenase from Lactobacillus casei, in particular from the Lactobacillus casei (DSM 20008).
    Type: Grant
    Filed: August 5, 1992
    Date of Patent: November 23, 1993
    Assignee: Kernforschungsanlage Juelich GmbH
    Inventors: Werner Hummel, Udo Wendel, Peter Schadewaldt