Abstract: The invention relates to a method of detecting p53-specific antibodies in body fluids wherein support-bound p53 and/or support-bound fragments thereof comprising binding regions for p53-specific antibodies are incubated with body fluids and the specific antibodies (a) bound to p53 and/or said fragments are allowed to reactwith labelled antibodies (b) directed against antibodies (a), orwith unlabelled antibodies (b) while the latter are allowed to react with labelled antibodies (c) directed against antibodies (b), with the labelling being non-radioactive in either case.The invention further relates to a kit useful therefor. Also, the invention relates to p53 fragments and DNA sequences coding for them, said fragments comprising binding regions for p53-specific antibodies, as well as to methods of preparing them.

Abstract: A method and system for the transmission of data in an electric distribution system between a central controller coupled to a medium-voltage distribution line and at least one terminal coupled to a low-voltage wherein, the transmission of data within the medium-voltage distribution line takes place at a first carrier frequency (f.sub.1), and the data at the first carrier frequency is transposed to data at a lower second carrier frequency (f.sub.21, f.sub.22) for transmission from the medium-voltage distribution line to the low-voltage distribution line by means of a transponder. Due to this transposing of carrier frequencies, the system can be optimized with respect to the different channel properties of the two communication channels.