Patents by Inventor Peter Scott Mountford

Peter Scott Mountford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation, selection and propagation of animal transgenic stem cells
    Patent number: 7459600
    Abstract: Animal stem cells are obtained and maintained by culturing cells containing, in the genome, a selectable marker. Differential expression of the selectable marker enables preferential survival and/or division of the desired stem cells compared to the non-stem cells.
    Type: Grant
    Filed: August 1, 2007
    Date of Patent: December 2, 2008
    Assignee: The University of Edinburgh
    Inventors: Austin Gerard Smith, Peter Scott Mountford
  • Isolation, selection and propagation of animal transgenic stem cells
    Patent number: 7256041
    Abstract: Animal stem cells are obtained and maintained by culturing cells containing, in the genome, a selectable marker. Differential expression of the selectable marker enables preferential survival and/or division of the desired stem cells compared to the non-stem cells.
    Type: Grant
    Filed: March 21, 2005
    Date of Patent: August 14, 2007
    Assignee: The University of Edinburgh
    Inventors: Austin Gerard Smith, Peter Scott Mountford
  • Expression of heterologous genes according to a targeted expression profile
    Patent number: 7005299
    Abstract: A gene trap vector comprises a DNA construct containing an expression unit of an internal ribosome binding site (IRES) coupled to a heterologous gene sequence; this expression unit is used in gene trap protocols to obtain expression of the heterologous gene in the host.
    Type: Grant
    Filed: July 7, 1999
    Date of Patent: February 28, 2006
    Assignee: The University of Edinburgh
    Inventors: Austin Gerard Smith, Peter Scott Mountford, Richard Frank Lathe
  • Isolation, selection and propagation of animal transgenic stem cells
    Patent number: 6878542
    Abstract: Animal stem cells are obtained and maintained by culturing cells containing, in the genome, a selectable marker; differential expression of the selectable marker enables preferential survival and/or division of the desired stem cells compared to non-stem cells.
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: April 12, 2005
    Assignee: The University of Edinburgh
    Inventors: Austin Gerard Smith, Peter Scott Mountford
  • Expression of the heterologous genes according to a targeted expression profile
    Patent number: 6150169
    Abstract: This invention relates to DNA constructs for inserting heterologous gene sequences into a host genome so as to obtain expression of the heterologous gene, to methods of inserting heterologous gene sequences into a host genome, and to organisms carrying modified host genomes. Specifically, the DNA constructs of this invention contain an expression unit of an internal ribosome binding site (IRES) coupled to a heterologous gene sequence. This expression unit is flanked at the 5' and 3' ends by DNA sequences that enable homologous recombination or integration of the construct with the DNA of a targeted host to obtain expression of the heterologous gene in the host.
    Type: Grant
    Filed: January 25, 1996
    Date of Patent: November 21, 2000
    Assignee: The University of Edinburgh
    Inventors: Austin Gerard Smith, Peter Scott Mountford, Richard Frank Lathe
  • Method of enriching for mammalian stem cells
    Patent number: 6146888
    Abstract: Mammalian stem cells are obtained and maintained in vitro whose genome has at least one nucleic acid construct encoding an antibiotic resistance gene operatively linked to a promoter specific for mammalian stem cells. The preferential expression of the antibiotic resistance gene in the stem cells results in the preferential survival of the stem cells in the presence of antibiotic.
    Type: Grant
    Filed: December 29, 1995
    Date of Patent: November 14, 2000
    Assignee: The University of Edinburgh
    Inventors: Austin Gerard Smith, Peter Scott Mountford