Patents by Inventor Peter Scott Vallack Single

Peter Scott Vallack Single has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12369826
    Abstract: Measuring a neural response to a stimulus comprises applying an electrical stimulus, then imposing a delay during which the stimulus electrodes are open circuited. During the delay, a neural response signal present at sense electrodes is measured with a measurement amplifier, while ensuring that an impedance between the sense electrodes is sufficiently large that a voltage arising on the sense electrode tissue interface in response to the stimulus is constrained to a level which permits assessment of the neural response voltage seen at the sense electrode. For example the input impedance to the measurement amplifier (ZIN) can be, where ZC is the sense electrode(s) constant phase element impedance, Vs1?Vs2 is the differential voltage arising on the sense electrode tissue interface, and VE is the neural response voltage seen at the sense electrode.
    Type: Grant
    Filed: July 28, 2022
    Date of Patent: July 29, 2025
    Assignee: Saluda Medical Pty Ltd
    Inventor: Peter Scott Vallack Single
  • Publication number: 20250213866
    Abstract: A multi-active-implantable-medical-device therapy system is disclosed, comprising a closed-loop neural stimulation (CLNS) device and a second active medical device. The CLNS device is configured to repeatedly execute a first activity, which involves delivering neural stimuli according to a stimulus parameter, measuring the intensities of responses evoked by the stimuli, and adjusting the stimulus parameter value to maintain the measured evoked response intensity at or near a target value. The second active medical device is configured to repeatedly execute a second activity. The system also includes a tracking device in communication with the CLNS device, which is configured to monitor a shared medium of the system to estimate the timing of the second activity. Based on the timing of the second activity, the CLNS device adjusts the timing of the first activity to mitigate interference from the second activity, thereby ensuring the effective execution of the first activity according to the adjusted timing.
    Type: Application
    Filed: December 26, 2024
    Publication date: July 3, 2025
    Inventors: Peter Hubertus Aigner, Jeffrey Yeu-Fai Tsang, Thomas Michael Damjanovic, Mohsen Nabipoor, Robert Bruce Gorman, Peter Scott Vallack Single, Joseph Michael Flay
  • Patent number: 12343147
    Abstract: A method for controlling electrical conditions of tissue in relation to a current stimulus. A first current produced by a first current source is delivered to the tissue via a current injection electrode. A second current drawn by a second current source is extracted from the tissue via a current extraction electrode. The second current source is matched with the first current source so as to balance the first current and the second current. A ground electrode which is proximal to the current injection electrode and the current extraction electrode is grounded, to provide a ground path for any mismatch current between the first current and second current. A response of the tissue to the current stimulus is measured via at least one measurement electrode.
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: July 1, 2025
    Assignee: Saluda Medical Pty Ltd
    Inventor: Peter Scott Vallack Single
  • Patent number: 12329971
    Abstract: Disclosed is a method of adapting the operation of an implantable device for delivering neurostimulation therapy to a patient. The method comprises: delivering the neurostimulation therapy to electrically excitable tissue of the patient according to at least one therapy parameter; measuring a physiological characteristic of the patient; adjusting the at least one therapy parameter according to a schedule of adjustment and the measured physiological characteristic; and repeating the delivering, measuring, and adjusting.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: June 17, 2025
    Assignee: Saluda Medical Pty Ltd
    Inventors: John Louis Parker, Peter Scott Vallack Single, Dean Michael Karantonis, Matthew Marlon Williams, Daniel John Parker, Samuel Nicholas Gilbert
  • Patent number: 12279872
    Abstract: A method for measuring a neural response to a stimulus. Measurement circuitry is settled prior to a stimulus, by connecting a sense electrode to the measurement circuitry to allow the measurement circuitry to settle towards a bio-electrically defined steady state. Charge is recovered on stimulus electrodes by short circuiting the stimulus electrodes to each other. An electrical stimulus is then applied from the stimulus electrodes to neural tissue, while keeping the sense electrode disconnected from the measurement circuitry. After the stimulus, a delay is imposed during which the stimulus electrodes are open circuited and the sense electrode is disconnected from the measurement circuitry and from the stimulus electrodes. After the delay, a neural response signal present at the sense electrode is measured by connecting the sense electrode to the measurement circuitry.
    Type: Grant
    Filed: June 10, 2024
    Date of Patent: April 22, 2025
    Assignee: Saluda Medical Pty Ltd
    Inventors: John Louis Parker, Peter Scott Vallack Single, Dean Michael Karantonis
  • Patent number: 12257056
    Abstract: A method for measuring a neural response to a stimulus. Measurement circuitry is settled prior to a stimulus, by connecting a sense electrode to the measurement circuitry to allow the measurement circuitry to settle towards a bio-electrically defined steady state. Charge is recovered on stimulus electrodes by short circuiting the stimulus electrodes to each other. An electrical stimulus is then applied from the stimulus electrodes to neural tissue, while keeping the sense electrode disconnected from the measurement circuitry. After the stimulus, a delay is imposed during which the stimulus electrodes are open circuited and the sense electrode is disconnected from the measurement circuitry and from the stimulus electrodes. After the delay, a neural response signal present at the sense electrode is measured by connecting the sense electrode to the measurement circuitry.
    Type: Grant
    Filed: June 10, 2024
    Date of Patent: March 25, 2025
    Assignee: Saluda Medical Pty Ltd
    Inventors: John Louis Parker, Peter Scott Vallack Single, Dean Michael Karantonis
  • Publication number: 20250050110
    Abstract: Disclosed are methods and devices for analysing signal windows captured subsequent to delivered neural stimuli and for providing a quality score for each signal window. The quality score is indicative of how closely the captured signal window resembles, or how likely that the captured signal window contains, an ECAP. The quality score may be provided to a process supervising a feedback loop of the closed-loop neural stimulation device delivering the stimuli and capturing the signal windows to ensure the delivered stimuli are appropriate. For example, if the score falls below a predetermined threshold, the supervisor may take a mitigation action to prevent inappropriate adjustment to the intensity of the delivered stimuli by the feedback loop, such as suspending operation of the feedback loop.
    Type: Application
    Filed: December 23, 2022
    Publication date: February 13, 2025
    Inventors: Matthew Marlon Williams, Daniel John Parker, Samuel Nicholas Gilbert, Dean Michael Karantonis, Milan Obradovic, Peter Scott Vallack Single
  • Publication number: 20250001180
    Abstract: There is provided a method of controlling a neural stimulus. The neural stimulus is defined by at least one stimulus parameter. The method comprises generating a neural stimulus for application to a neural tissue of a patient in accordance with a stimulus parameter, at a first stimulus intensity level, and measuring a response of the neural tissue, the response being evoked by the neural stimulus. The method further comprises determining a second stimulus intensity level, based on an activation plot intercept point, the first stimulus intensity level, the measured response of the neural tissue and a target recruitment level, and adjusting the at least one stimulus parameter to the second stimulus intensity level.
    Type: Application
    Filed: June 28, 2022
    Publication date: January 2, 2025
    Inventor: Peter Scott Vallack Single
  • Publication number: 20240382758
    Abstract: A neuromodulation system and method. An implantable electrode array comprises a plurality of electrodes. A stimulus source provides neural stimuli delivered via stimulus electrodes to neural tissue to evoke neural responses. Measurement circuitry captures signal windows sensed from the neural tissue subsequent to each stimulus. A control unit controls the neural stimuli according to a stimulus intensity parameter. A processor introduces a perturbation to the parameter from a baseline stimulus intensity. A time series of intensities of the evoked neural responses is obtained. from which a time series of estimates of at least one physiological characteristic of the neural tissue is obtained. Each physiological characteristic being variable as a result of a posture wave. A baseline value of each physiological characteristic is estimated from the time series of estimates of each physiological characteristic.
    Type: Application
    Filed: September 12, 2022
    Publication date: November 21, 2024
    Inventors: Peter Scott Vallack Single, Robert Bruce Gorman, Daniel John Parker, Samuel Nicholas Gilbert, Thomas Michael Damjanovic
  • Publication number: 20240366941
    Abstract: Disclosed is an implantable neural stimulation device, the device comprising: an electrode array comprising a plurality of electrodes, the electrodes comprising a first stimulus electrode and a second stimulus electrode; a pulse generator connectable to the stimulus electrodes, the pulse generator configured to generate a multiphasic stimulus pulse of current from a supply voltage and deliver the multiphasic stimulus pulse via the stimulus electrodes to an electrically excitable tissue in order to evoke a neural response on a neural pathway in the electrically excitable tissue; and modulation circuitry connectable to a regulation electrode of the plurality of electrodes, the modulation circuitry configured to modulate a voltage on the regulation electrode during the delivery of the multiphasic stimulus pulse such that a corresponding voltage on each stimulus electrode varies substantially symmetrically around a value which is about half the supply voltage over the multiphasic stimulus pulse.
    Type: Application
    Filed: August 30, 2022
    Publication date: November 7, 2024
    Inventor: Peter Scott Vallack Single
  • Patent number: 12121715
    Abstract: A method (100) of manufacturing a lead for an implantable medical device. The method includes: depositing (110) a base layer (3) of biocompatible, electrically non-conductive material; depositing (120) one or more complementary layers (5) of biocompatible, electrically non-conductive material to the base layer (3), wherein the base layer (3) and complementary layer (5) form at least one slot (7); and depositing (130) biocompatible, electrically conductive material (9) into the slot (7). There is also disclosed a lead for an implantable medical device and an apparatus (41) to manufacture the lead.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: October 22, 2024
    Assignee: Saluda Medical Pty Limited
    Inventors: John Louis Parker, Mohammadjavad Sadeghi, Peter Scott Vallack Single
  • Publication number: 20240277274
    Abstract: An implantable device for estimating neural recruitment arising from a stimulus, has a plurality of electrodes. A stimulus source provides stimuli to be delivered from the electrodes to neural tissue. Measurement circuitry obtains a measurement of a neural signal sensed at the electrodes. A control unit is configured to control application of a selected stimulus to neural tissue using the stimulus electrodes; and after the selected neural stimulus, apply a probe stimulus having a short pulse width. A remnant neural response evoked by the probe stimulus is measured; and the control unit estimates from the remnant neural response a neural recruitment caused by the selected neural stimulus.
    Type: Application
    Filed: February 28, 2024
    Publication date: August 22, 2024
    Inventors: John Louis Parker, James Hamilton Wah, Dean Michael Karantonis, Peter Scott Vallack Single
  • Patent number: 12064632
    Abstract: A method of controlling a neural stimulus by use of feedback. The neural stimulus is applied to a neural pathway in order to give rise to an evoked action potential on the neural pathway. The stimulus is defined by at least one stimulus parameter. A neural compound action potential response evoked by the stimulus is measured. From the measured evoked response a feedback variable is derived. A feedback loop is completed by using the feedback variable to control the at least one stimulus parameter value. The feedback loop adaptively compensates for changes in a gain of the feedback loop caused by electrode movement relative to the neural pathway.
    Type: Grant
    Filed: August 8, 2022
    Date of Patent: August 20, 2024
    Assignee: Saluda Medical Pty Ltd
    Inventors: Peter Scott Vallack Single, Dean Michael Karantonis
  • Patent number: 12048564
    Abstract: A method for processing a neural measurement obtained in the presence of artifact, in order to detect whether a neural response is present in the neural measurement. A neural measurement is obtained from one or more sense electrodes. The neural measurement is correlated against a filter template, the filter template comprising at least three half cycles of an alternating waveform, amplitude modulated by a window. From an output of the correlating, it is determined whether a neural response is present in the neural measurement.
    Type: Grant
    Filed: December 21, 2023
    Date of Patent: July 30, 2024
    Assignee: Saluda Medical Pty Ltd
    Inventors: Peter Scott Vallack Single, Dean Michael Karantonis
  • Publication number: 20240189599
    Abstract: Disclosed is a device for recording evoked neural responses. The device comprises: a plurality of electrodes including one or more stimulus electrodes, a first sense electrode, and a second sense electrode; a stimulus source for providing a stimulus to be delivered via the one or more stimulus electrodes to a neural pathway in order to evoke a compound action potential on the neural pathway; measurement circuitry for processing a signal sensed at the first sense electrode and second sense electrode, the sensed signal comprising the evoked compound action potential; and impedance compensation means configured to compensate for an impedance difference, the impedance difference being a difference between an impedance associated with the first sense electrode and an impedance associated with the second sense electrode.
    Type: Application
    Filed: April 14, 2022
    Publication date: June 13, 2024
    Applicant: Saluda Medical Pty Ltd
    Inventors: Peter Scott Vallack Single, Jonathan Brereton Scott, Joanne Carol Shiels Olecko
  • Publication number: 20240172985
    Abstract: A neural stimulus comprises at least three stimulus components, each comprising at least one of a temporal stimulus phase and a spatial stimulus pole. A first stimulus component delivers a first charge which is unequal to a third charge delivered by a third stimulus component, and the first charge and third charge are selected so as to give rise to reduced artefact at recording electrodes. In turn this may be exploited to independently control a correlation delay of a vector detector and an artefact vector to be non-parallel or orthogonal.
    Type: Application
    Filed: October 19, 2023
    Publication date: May 30, 2024
    Applicant: Saluda Medical Pty Ltd
    Inventors: Dean Michael Karantonis, Peter Scott Vallack Single, Kai Huang
  • Patent number: 11944439
    Abstract: An implantable device for controlling electrical conditions of body tissue. A feedback sense electrode and a compensation electrode are positioned proximal to the tissue to make electrical contact with the tissue. A feedback amplifier is referenced to ground, and takes as an input a feedback signal from the feedback sense electrode. The output of the feedback amplifier is connected to the compensation electrode. The feedback amplifier thus drives the neural tissue via the compensation electrode in a feedback arrangement which seeks to drive the feedback signal to ground, or other desired electrical value.
    Type: Grant
    Filed: May 23, 2022
    Date of Patent: April 2, 2024
    Assignee: Saluda Medical Pty Ltd
    Inventors: Peter Scott Vallack Single, James Hamilton Wah
  • Patent number: 11944440
    Abstract: An implantable device for estimating neural recruitment arising from a stimulus, has a plurality of electrodes. A stimulus source provides stimuli to be delivered from the electrodes to neural tissue. Measurement circuitry obtains a measurement of a neural signal sensed at the electrodes. A control unit is configured to control application of a selected stimulus to neural tissue using the stimulus electrodes; and after the selected neural stimulus, apply a probe stimulus having a short pulse width. A remnant neural response evoked by the probe stimulus is measured; and the control unit estimates from the remnant neural response a neural recruitment caused by the selected neural stimulus.
    Type: Grant
    Filed: August 22, 2022
    Date of Patent: April 2, 2024
    Assignee: Saluda Medical Pty Ltd
    Inventors: John Louis Parker, James Hamilton Wah, Dean Michael Karantonis, Peter Scott Vallack Single
  • Patent number: 11890113
    Abstract: A method for processing a neural measurement obtained in the presence of artifact, in order to detect whether a neural response is present in the neural measurement. A neural measurement is obtained from one or more sense electrodes. The neural measurement is correlated against a filter template, the filter template comprising at least three half cycles of an alternating waveform, amplitude modulated by a window. From an output of the correlating, it is determined whether a neural response is present in the neural measurement.
    Type: Grant
    Filed: April 8, 2022
    Date of Patent: February 6, 2024
    Assignee: Saluda Medical Pty Ltd
    Inventors: Peter Scott Vallack Single, Dean Michael Karantonis
  • Publication number: 20240033522
    Abstract: Recording evoked neural responses comprises delivering a stimulus from one or more stimulus electrodes to a neural pathway in order to give rise to an evoked compound action potential (ECAP) on the neural pathway. And, recording with measurement circuitry, during delivery of at least part of the stimulus, a neural compound action potential signal sensed at one or more sense electrodes. And, processing the recording of the neural compound action potential signal to determine at least one characteristic of the ECAP. At least one characteristic of the stimulus is then defined based on the determined at least one characteristic of the ECAP.
    Type: Application
    Filed: February 9, 2022
    Publication date: February 1, 2024
    Applicant: Saluda Medical Pty Ltd
    Inventors: Dean Michael Karantonis, Peter Scott Vallack Single, James Hamilton Wah